Enzymes for producing non-straight-chain fatty acids
Enzymes for producing non-straight-chain fatty acids, microorganisms comprising the enzymes, and in vivo and in vitro uses of the enzymes. Provided are enzymes capable of producing various non-straight-chain fatty acids, including branched-chain fatty acids, cyclic fatty acids, and furan-containing fatty acids. The enzymes include RSP2144, RSP1091, and RSP1090 from Rhodobacter sphaeroides and homologs thereof. The enzymes can be purified to produce non-straight-chain fatty acids in vitro or expressed in microorganisms to produce non-straight-chain fatty acids in vivo. The microorganisms can be fine-tuned to produce a specific type of non-straight-chain fatty acid by expressing, overexpressing, or deleting the enzymes in various combinations.
- Research Organization:
- Wisconsin Alumni Research Foundation, Madison, WI (United States)
- Sponsoring Organization:
- USDOE
- DOE Contract Number:
- FC02-07ER64494
- Assignee:
- Wisconsin Alumni Research Foundation (Madison, WI)
- Patent Number(s):
- 10,273,511
- Application Number:
- 14/755,213
- OSTI ID:
- 1568261
- Country of Publication:
- United States
- Language:
- English
Similar Records
Modular pathway engineering for the microbial production of branched-chain fatty alcohols