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Title: Zero voltage mass spectrometry probes and systems

Patent ·
OSTI ID:1568185
; ; ;

The invention generally relates to zero volt mass spectrometry probes and systems. In certain embodiments, the invention provides a system including a mass spectrometry probe including a porous material, and a mass spectrometer (bench-top or miniature mass spectrometer). The system operates without an application of voltage to the probe. In certain embodiments, the probe is oriented such that a distal end faces an inlet of the mass spectrometer. In other embodiments, the distal end of the probe is 5 mm or less from an inlet of the mass spectrometer.

Research Organization:
Purdue Univ., West Lafayette, IN (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-06ER15807
Assignee:
Purdue Research Foundation (West Lafayette, IN)
Patent Number(s):
10,256,085
Application Number:
15/697,560
OSTI ID:
1568185
Resource Relation:
Patent File Date: 09/07/2017
Country of Publication:
United States
Language:
English

References (129)

Process for the detection and quantitation of corrosion and scale inhibitors in produced well fluids patent October 1992
On-line/at-line monitoring of residual chemical by surface enhanced Raman spectroscopy patent October 2012
Analyzing Apparatus patent-application November 2013
Apparatus for the removal of an edge polymer from a substrate and methods therefor patent January 2010
Method and system for desorption atmospheric pressure chemical ionization patent-application December 2009
Fourtier transform quadrupole mass spectrometer and method patent July 1988
System for performing blood coagulation assays and measuring blood clotting times patent-application September 2003
Porous electrospray emitter patent-application December 2004
Data correction, normalization and validation for quantitative high-throughput metabolomic profiling patent-application September 2006
Ion Generation Using Wetted Porous Material patent-application May 2013
Apparatus and methods for continuous beam fourier transform mass spectrometry patent September 2002
Ion generation using wetted porous material patent August 2014
Zero voltage mass spectrometry probes and systems patent October 2017
Ionization Analysis Method and Apparatus patent-application May 2011
Mass spectrometry analysis of microorganisms in samples patent April 2014
Systems for Detecting Analytes patent-application May 2002
Ion Generation Using Wetted Porous Material patent-application January 2014
Chemical ionization reaction or proton transfer reaction mass spectrometry patent December 2012
Assembly for collecting samples for purposes of identification or analysis and method of use patent-application February 2007
Methods for solid phase nanoextraction and desorption patent-application March 2002
Ionization Emitter, Ionization Apparatus, and Method for Manufacturing Ionization Emitter patent-application March 2010
Biomarkers Useful for Diagnosing Prostate Cancer, and Methods Thereof patent-application May 2009
Low-temperature, converging, reactive gas source and method of use patent December 2012
Atmospheric-pressure plasma jet patent October 1999
Microfabricated ion trap array patent December 2006
Integrated monolithic microfabricated electrospray and liquid chromatography system and method patent-application September 2002
Method and system for desorption atmospheric pressure chemical ionization patent June 2009
Discontinuous atmospheric pressure interface patent November 2012
Time-of-flight bacteria analyser using metastable source ionization patent September 2003
Method and apparatus for an electrospray needle for use in mass spectrometry patent-application November 2005
Method and Apparatus for a Porous Metal Electrospray Emitter patent-application September 2011
Analysis of Hydrocarbon Liquid and Solid Samples patent-application June 2014
Interfacing Low-Flow Separation Techniques patent-application January 2010
Loop certification and measurement for ADSL patent November 2002
Methods of Making Substrates for Mass Spectrometry Analysis and Related Devices patent-application April 2005
Discontinuous Atmospheric Pressure Interface patent-application December 2010
Low temperature plasma probe and methods of use thereof patent August 2013
Remote testing of a communications line patent March 2006
Method and system for desorption electrospray ionization patent February 2008
Generation of Model-of-Composition of Petroleum by High Resolution Mass Spectrometry and Associated Analytics patent-application June 2012
Systems and methods for sample analysis patent October 2015
Ion Generation Using Wetted Porous Material patent-application May 2013
Adsorption, detection and identification of components of ambient air with desorption/ionization on silicon mass spectrometry (DIOS-MS) patent July 2009
Corrosion prevention with compositions prepared from organic fatty amines and nitrogen-containing aromatic heterocyclic compounds patent September 1990
System for the online measurement of volatile and semi-volatile compounds and use thereof patent April 2011
Methods and Devices for Concentration and Fractionation of Analytes for Chemical Analysis Including Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry (MS) patent-application March 2009
Electrospray emitter patent-application July 2003
Device including a dissolvable structure for flow control patent-application May 2006
Multiple sampling device and method for investigating biological systems patent August 2007
Ion Generation Using Wetted Porous Material patent-application May 2012
Ion generation using wetted porous material patent October 2014
Method of photometric in vitro determination of the content of an analyte in a sample of whole blood patent February 1994
Sample collection apparatus patent October 2011
Method of synthesis and delivery of complex pharmaceuticals, chemical substances and polymers through the process of electrospraying, electrospinning or extrusion utilizing holey fibers patent-application June 2005
Devices and methods for reduction of NOx emissions from lean burn engines patent-application July 2007
Ion source for a mass spectrometer patent November 1992
Soft ionization device and applications thereof patent-application July 2003
Apparatus and method for thermal assisted desorption ionization systems patent June 2014
Mass analyzing apparatus patent February 2010
Nebulizer with plasma source patent February 2006
Stabilized Whole Blood Standard and Method of Making the Same patent September 1961
Apparatus for holding solids for use with surface ionization technology patent May 2010
Ion generation using wetted porous material patent-application May 2013
Ion generation using modified wetted porous materials patent-application July 2014
Systems and methods for transfer of ions for analysis patent April 2013
Method and system for desorption atmospheric pressure chemical ionization patent-application August 2007
Electrospray Ionization Mass Spectrometry Methodology patent-application September 2010
Mass Spectrometer patent-application November 2008
Use of benzazoles as corrosion inhibitors patent November 1980
Quantification of analytes using internal standards patent-application May 2005
Ion mobility TOF/MALDI/MS using drift cell alternating high and low electrical field regions patent May 2007
Plasma treatment apparatus and plasma generation method using the apparatus patent October 2002
Method and device for evaluating the state of organisms and natural products and for analyzing a gaseous mixture comprising main constituents and secondary constituents patent January 2006
Telecommunications interruption and disconnection apparatus and methods patent January 2007
Ion Focusing and Detection in a Miniature Linear Ion Trap for Mass Spectrometry patent-application January 2010
On-line and off-line coupling of EC with DESI-MS patent December 2012
Apparatus, System and Method for Purifying Nucleic Acids patent-application May 2011
Mechanical Holder for Surface Analysis patent-application January 2012
Nanostructure-Initiator Mass Spectrometry patent-application June 2008
Ion generation using wetted porous material patent-application February 2014
Mass Spectrometer And Mass Analyzing Method patent-application December 2012
Microspray Liquid-Liquid Extractive Ionization Device patent-application July 2008
Solid-Phase Extraction (SPE) Tips and Methods of Use patent-application June 2011
Mass Spectrometry Probes Having Hydrophobic Coatings patent-application August 2008
Method and apparatus of liquid sample-desorption electrospray ionization-mass specrometry (LS-DESI-MS) patent March 2011
Laser desorption - electrospray ion (ESI) source for mass spectrometers patent-application November 2008
Self-blunting needle assembly and device including the same patent May 1989
Liquid cheromatography/mass spectrometry apparatus patent-application June 2006
Ion generation using modified wetted porous materials patent November 2014
Test tray, kit and methods for bodily fluid testing for newborn screening by tandem mass spectrometry patent-application October 2003
High Throughput Testing for Presence of Microorganisms in a Biological Sample patent-application December 2009
Ion mobility TOF/MALDI/MS using drift cell alternating high and low electrical field regions patent January 2006
Scanned Source Oriented Nanofiber Formation patent-application November 2009
Systems and methods for sample analysis patent January 2015
Apparatus and method for dispensing a sample patent-application April 2004
Combined electrophoresis-electrospray interface and method patent December 1989
Coupling of Liquid Chromatography with Mass Spectrometry by Liquid Sample Desorption Electrospray Ionization (DESI) patent-application January 2013
Methods and apparatus for porous membrane electrospray and multiplexed coupling of microfluidic systems with mass spectrometry patent-application August 2006
Mass analyzer system for the direct determination of organic compounds in PPB and high PPT concentrations in the gas phase patent July 1988
Microminiature gas chromatograph patent December 1996
Low temperature plasma probe and methods of use thereof patent July 2014
Low temperature plasma enhanced CVD ceramic coating process for metal, alloy and ceramic materials patent November 2002
Device for quantitative analysis of a drug or metabolite profile patent-application January 2007
Apparatus and method for ion production enhancement patent November 2006
Method and system for desorption atmospheric pressure chemical ionization patent December 2011
Method for Inhibiting Corrosion patent-application August 2011
Fingerprinting of Complex Hydrocarbon Containing Mixtures patent-application September 2008
Internal Standards Uniformly Dispersed in the Walls of a Container for Activation Analysis patent August 1967
Device for use in chemical test procedures patent August 1992
Ion generation using wetted porous material patent April 2014
Analyzing a Metabolite Level in a Sample patent-application October 2013
Method and apparatus for an electrospray needle for use in mass spectrometry patent-application January 2004
Multidimensional mass spectrometry of serum and cellular lipids directly from biologic extracts patent March 2009
Surface charging to improve wettability patent August 1998
Micro-devices and analytical procedures for investigation of biological systems patent June 2008
Methods and systems for quantification of peptides and other analytes patent-application April 2009
Electrospray Device And A Method of Electrospraying patent-application June 2009
Mass Analyzing Apparatus patent-application November 2008
Membrane for holding samples for use with surface ionization technology patent July 2013
Automatic Detection of Quality Spectra patent-application November 2006
Method and apparatus for electrospray ionization patent October 2001
Device and Method for Introducing Multiple Liquid Samples at Atmospheric Pressure for Mass Spectrometry patent-application April 2008
Ion generation using wetted porous material patent October 2014
Mercaptoalcohol corrosion inhibitors patent November 2003
Ion generation using wetted porous material patent October 2014
Gas sampler for molten metal and method patent April 2001
Ion generation using wetted porous material patent October 2014
Biological measurement system patent June 2008
Mass Spectrometer patent-application May 2010

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