skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Transcriptomic analysis of skin pigmentation variation in the Virginia opossum ( Didelphis virginiana )


Not provided.

ORCiD logo [1];  [2];  [3];  [4];  [5];  [1]
  1. Department of Ecology and Evolutionary Biology, University of California, Los Angeles, Los Angeles California
  2. Key Lab of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Chaoyang, Beijing China
  3. Savannah River Ecology Lab, Warnell School of Forestry and Natural Resources, University of Georgia, Aiken South Carolina
  4. Centro de Investigaciones Regionales “Dr. Hideyo Noguchi”, Universidad Autónoma de Yucatán, Mérida Yucatán Mexico
  5. Departamento de Ecología Evolutiva, Centro de Investigación en Biodiversidad y Conservación, Universidad Autónoma del Estado de Morelos, Cuernavaca Morelos Mexico
Publication Date:
Research Org.:
Univ. of Georgia, Athens, GA (United States)
Sponsoring Org.:
USDOE Office of Environmental Management (EM)
OSTI Identifier:
DOE Contract Number:  
Resource Type:
Journal Article
Journal Name:
Molecular Ecology
Additional Journal Information:
Journal Volume: 27; Journal Issue: 12; Journal ID: ISSN 0962-1083
Country of Publication:
United States
Biochemistry & Molecular Biology; Environmental Sciences & Ecology; Evolutionary Biology

Citation Formats

Nigenda-Morales, Sergio F., Hu, Yibo, Beasley, James C., Ruiz-Piña, Hugo A., Valenzuela-Galván, David, and Wayne, Robert K. Transcriptomic analysis of skin pigmentation variation in the Virginia opossum ( Didelphis virginiana ). United States: N. p., 2018. Web. doi:10.1111/mec.14712.
Nigenda-Morales, Sergio F., Hu, Yibo, Beasley, James C., Ruiz-Piña, Hugo A., Valenzuela-Galván, David, & Wayne, Robert K. Transcriptomic analysis of skin pigmentation variation in the Virginia opossum ( Didelphis virginiana ). United States. doi:10.1111/mec.14712.
Nigenda-Morales, Sergio F., Hu, Yibo, Beasley, James C., Ruiz-Piña, Hugo A., Valenzuela-Galván, David, and Wayne, Robert K. Fri . "Transcriptomic analysis of skin pigmentation variation in the Virginia opossum ( Didelphis virginiana )". United States. doi:10.1111/mec.14712.
title = {Transcriptomic analysis of skin pigmentation variation in the Virginia opossum ( Didelphis virginiana )},
author = {Nigenda-Morales, Sergio F. and Hu, Yibo and Beasley, James C. and Ruiz-Piña, Hugo A. and Valenzuela-Galván, David and Wayne, Robert K.},
abstractNote = {Not provided.},
doi = {10.1111/mec.14712},
journal = {Molecular Ecology},
issn = {0962-1083},
number = 12,
volume = 27,
place = {United States},
year = {2018},
month = {6}

Works referenced in this record:

Ten years of transcriptomics in wild populations: what have we learned about their ecology and evolution?
journal, January 2015

  • Alvarez, Mariano; Schrey, Aaron W.; Richards, Christina L.
  • Molecular Ecology, Vol. 24, Issue 4
  • DOI: 10.1111/mec.13055

HTSeq--a Python framework to work with high-throughput sequencing data
journal, September 2014

Molecular and Evolutionary History of Melanism in North American Gray Wolves
journal, March 2009

THE NF-κB AND IκB PROTEINS: New Discoveries and Insights
journal, April 1996

Paleoclimate simulations for North America over the past 21,000 years
journal, April 1998

The Tyr (albino) locus of the laboratory mouse
journal, October 2004

The Color Loci of Mice - A Genetic Century
journal, August 2003

QuickGO: a web-based tool for Gene Ontology searching
journal, September 2009

Nek2A destruction marks APC/C activation at the prophase-to-prometaphase transition by spindle-checkpoint-restricted Cdc20
journal, February 2015

  • Boekhout, M.; Wolthuis, R.
  • Journal of Cell Science, Vol. 128, Issue 8
  • DOI: 10.1242/jcs.163279

The two NF-κB activation pathways and their role in innate and adaptive immunity
journal, June 2004

The Adaptiveness of Animal Colors
journal, November 1981

Gloger'S Rule, Feather-Degrading Bacteria, and Color Variation Among song Sparrows
journal, January 2004

  • Burtt, Edward H.; Ichida, Jann M.
  • The Condor, Vol. 106, Issue 3
  • DOI: 10.1650/7383

The Adaptive Significance of Coloration in Mammals
journal, January 2005

Cathepsins: Key modulators of cell death and inflammatory responses
journal, December 2008

Modeling Effects of Environmental Change on Wolf Population Dynamics, Trait Evolution, and Life History
journal, December 2011

DC-SIGN activation mediates the differential effects of SAP and CRP on the innate immune system and inhibits fibrosis in mice
journal, June 2015

  • Cox, Nehemiah; Pilling, Darrell; Gomer, Richard H.
  • Proceedings of the National Academy of Sciences, Vol. 112, Issue 27
  • DOI: 10.1073/pnas.1500956112

The biology of color
journal, August 2017

Cathepsin H Is an Additional Convertase of Pro-granzyme B
journal, April 2010

  • D'Angelo, Michael E.; Bird, Phillip I.; Peters, Christoph
  • Journal of Biological Chemistry, Vol. 285, Issue 27
  • DOI: 10.1074/jbc.M109.094573

Fur versus feathers: the different roles of red kangaroo fur and emu feathers in thermoregulation in the Australian arid zone.
journal, January 2004

  • Dawson, Tj; Maloney, Sk
  • Australian Mammalogy, Vol. 26, Issue 2
  • DOI: 10.1071/AM04145

The fur of mammals in exposed environments; do crypsis and thermal needs necessarily conflict? The polar bear and marsupial koala compared
journal, December 2013

  • Dawson, Terence J.; Webster, Koa N.; Maloney, Shane K.
  • Journal of Comparative Physiology B, Vol. 184, Issue 2
  • DOI: 10.1007/s00360-013-0794-8

A review of genetic disorders of hypopigmentation: lessons learned from the biology of melanocytes
journal, September 2009

Social huddling and physiological thermoregulation are related to melanism in the nocturnal barn owl
journal, November 2015

Pleiotropy in the melanocortin system, coloration and behavioural syndromes
journal, September 2008

Applications of next generation sequencing in molecular ecology of non-model organisms
journal, December 2010

The skin barrier as an innate immune element
journal, March 2007

Pleiotropy in the melanocortin system: expression levels of this system are associated with melanogenesis and pigmentation in the tawny owl ( Strix aluco )
journal, August 2013

  • Emaresi, Guillaume; Ducrest, Anne-Lyse; Bize, Pierre
  • Molecular Ecology, Vol. 22, Issue 19
  • DOI: 10.1111/mec.12438

On the measurement and classification of colour in studies of animal colour patterns
journal, December 1990

Phenotypic plasticity can facilitate adaptive evolution in gene regulatory circuits
journal, January 2011

  • Espinosa-Soto, Carlos; Martin, Olivier C.; Wagner, Andreas
  • BMC Evolutionary Biology, Vol. 11, Issue 1
  • DOI: 10.1186/1471-2148-11-5

Animal models of vitiligo: Matching the model to the question
journal, December 2014

SKAP associates with kinetochores and promotes the metaphase-to-anaphase transition
journal, September 2009

Gene Coexpression Networks Reveal Key Drivers of Phenotypic Divergence in Lake Whitefish
journal, March 2013

  • Filteau, Marie; Pavey, Scott A.; St-Cyr, Jérôme
  • Molecular Biology and Evolution, Vol. 30, Issue 6
  • DOI: 10.1093/molbev/mst053

Gene expression drives local adaptation in humans
journal, March 2013

Genome-wide expression reveals multiple systemic effects associated with detection of anticoagulant poisons in bobcats ( Lynx rufus )
journal, March 2018

  • Fraser, Devaughn; Mouton, Alice; Serieys, Laurel E. K.
  • Molecular Ecology, Vol. 27, Issue 5
  • DOI: 10.1111/mec.14531

Pax3 and Regulation of the Melanocyte-specific Tyrosinase-related Protein-1 Promoter
journal, September 1999

  • Galibert, Marie-Dominique; Yavuzer, Ugur; Dexter, Timothy J.
  • Journal of Biological Chemistry, Vol. 274, Issue 38
  • DOI: 10.1074/jbc.274.38.26894

Dishevelled: The hub of Wnt signaling
journal, May 2010

Ecogeographical rules: elements of a synthesis
journal, March 2008

Integrating Genetic and Network Analysis to Characterize Genes Related to Mouse Weight
journal, January 2006

Characterizing natural variation using next-generation sequencing technologies
journal, October 2009

Spatial Response of Mammals to Late Quaternary Environmental Fluctuations
journal, June 1996

Compelling evidence that a single nucleotide substitution in TYRP1 is responsible for coat-colour polymorphism in a free-living population of Soay sheep
journal, December 2006

  • Gratten, J.; Beraldi, D.; Lowder, B. V.
  • Proceedings of the Royal Society B: Biological Sciences, Vol. 274, Issue 1610
  • DOI: 10.1098/rspb.2006.3762

The Prehistoric Distribution of the Opossum
journal, February 1958

  • Guilday, John E.
  • Journal of Mammalogy, Vol. 39, Issue 1
  • DOI: 10.2307/1376607

Evidence for dynamically organized modularity in the yeast protein–protein interaction network
journal, June 2004

  • Han, Jing-Dong J.; Bertin, Nicolas; Hao, Tong
  • Nature, Vol. 430, Issue 6995
  • DOI: 10.1038/nature02555

Adaptations to Climate-Mediated Selective Pressures in Humans
journal, April 2011

Removing technical variability in RNA-seq data using conditional quantile normalization
journal, January 2012

TimeTree: a public knowledge-base of divergence times among organisms
journal, October 2006

Tree of Life Reveals Clock-Like Speciation and Diversification
journal, March 2015

  • Hedges, S. Blair; Marin, Julie; Suleski, Michael
  • Molecular Biology and Evolution, Vol. 32, Issue 4
  • DOI: 10.1093/molbev/msv037

Genetics, development and evolution of adaptive pigmentation in vertebrates
journal, July 2006

A Single Amino Acid Mutation Contributes to Adaptive Beach Mouse Color Pattern
journal, July 2006

  • Hoekstra, Hopi E.; Hirschmann, Rachel J.; Bundey, Richard A.
  • Science, Vol. 313, Issue 5783
  • DOI: 10.1126/science.1126121

Geometric Interpretation of Gene Coexpression Network Analysis
journal, August 2008

Analysis of oncogenic signaling networks in glioblastoma identifies ASPM as a molecular target
journal, November 2006

  • Horvath, S.; Zhang, B.; Carlson, M.
  • Proceedings of the National Academy of Sciences, Vol. 103, Issue 46
  • DOI: 10.1073/pnas.0608396103

Vertebrate pigmentation: from underlying genes to adaptive function
journal, May 2010

Human skin pigmentation as an adaptation to UV radiation
journal, May 2010

  • Jablonski, N. G.; Chaplin, G.
  • Proceedings of the National Academy of Sciences, Vol. 107, Issue Supplement_2
  • DOI: 10.1073/pnas.0914628107

Cone pigments in a North American marsupial, the opossum (Didelphis virginiana)
journal, March 2010

Seasonal gene expression in a migratory songbird
journal, November 2016

  • Johnston, Rachel A.; Paxton, Kristina L.; Moore, Frank R.
  • Molecular Ecology, Vol. 25, Issue 22
  • DOI: 10.1111/mec.13879

TopHat2: accurate alignment of transcriptomes in the presence of insertions, deletions and gene fusions
journal, January 2013

Expressional changes in the intracellular melanogenesis pathways and their possible role the pathogenesis of vitiligo
journal, October 2008

TissueDistributionDBs: a repository of organism-specific tissue-distribution profiles
journal, November 2009

  • Kogenaru, Sunitha; del Val, Coral; Hotz-Wagenblatt, Agnes
  • Theoretical Chemistry Accounts, Vol. 125, Issue 3-6
  • DOI: 10.1007/s00214-009-0670-5

Variation of coat color in house mice throughout Asia
journal, March 2008

WGCNA: an R package for weighted correlation network analysis
journal, December 2008

When Is Hub Gene Selection Better than Standard Meta-Analysis?
journal, April 2013

Defining clusters from a hierarchical cluster tree: the Dynamic Tree Cut package for R
journal, November 2007

How the zebra got its stripes: a problem with too many solutions
journal, January 2015

  • Larison, Brenda; Harrigan, Ryan J.; Thomassen, Henri A.
  • Royal Society Open Science, Vol. 2, Issue 1
  • DOI: 10.1098/rsos.140452

voom: precision weights unlock linear model analysis tools for RNA-seq read counts
journal, January 2014

Melanocyte biology and skin pigmentation
journal, February 2007

On the Origin and Spread of an Adaptive Allele in Deer Mice
journal, August 2009

Adaptive Evolution of Multiple Traits Through Multiple Mutations at a Single Gene
journal, March 2013

TiGER: a database for tissue-specific gene expression and regulation
journal, January 2008

The wnt Signaling Pathway in Development and Disease
journal, November 2004

MEF up-regulates human β-defensin 2 expression in epithelial cells
journal, March 2004

The Antimicrobial Properties of Melanocytes, Melanosomes and Melanin and the Evolution of Black Skin
journal, July 2001

Convergence in pigmentation at multiple levels: mutations, genes and function
journal, August 2010

  • Manceau, Marie; Domingues, Vera S.; Linnen, Catherine R.
  • Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 365, Issue 1552
  • DOI: 10.1098/rstb.2010.0104

Emerging infectious disease selects for darker plumage coloration in greenfinches
journal, March 2014

Didelphis virginiana
journal, May 1974

The comparative energetics of neotropical marsupials
journal, January 1978

  • McNab, Brian K.
  • Journal of Comparative Physiology B, Vol. 125, Issue 2
  • DOI: 10.1007/BF00686747

Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences
journal, May 2007

  • Mikkelsen, Tarjei S.; Wakefield, Matthew J.; Aken, Bronwen
  • Nature, Vol. 447, Issue 7141
  • DOI: 10.1038/nature05805

A Systems Level Analysis of Transcriptional Changes in Alzheimer's Disease and Normal Aging
journal, February 2008

Polar and brown bear genomes reveal ancient admixture and demographic footprints of past climate change
journal, July 2012

  • Miller, W.; Schuster, S. C.; Welch, A. J.
  • Proceedings of the National Academy of Sciences, Vol. 109, Issue 36
  • DOI: 10.1073/pnas.1210506109

Ecotypic variation in the context of global climate change: revisiting the rules
journal, July 2006

CD163: a regulated hemoglobin scavenger receptor with a role in the anti‐inflammatory response
journal, January 2004

Natural Selection Along an Environmental Gradient: a Classic Cline in Mouse Pigmentation
journal, July 2008

Evolution of an avian pigmentation gene correlates with a measure of sexual selection
journal, May 2007

  • Nadeau, Nicola J.; Burke, Terry; Mundy, Nicholas I.
  • Proceedings of the Royal Society B: Biological Sciences, Vol. 274, Issue 1620
  • DOI: 10.1098/rspb.2007.0174

The complement system: History, pathways, cascade and inhibitors
journal, June 2012

  • Nesargikar, Prabhu; Spiller, B.; Chavez, R.
  • European Journal of Microbiology and Immunology, Vol. 2, Issue 2
  • DOI: 10.1556/EuJMI.2.2012.2.2

Darwinian and demographic forces affecting human protein coding genes
journal, March 2009

Playing by the rules? Phenotypic adaptation to temperate environments in an American marsupial
journal, January 2018

  • Nigenda-Morales, Sergio F.; Harrigan, Ryan J.; Wayne, Robert K.
  • PeerJ, Vol. 6
  • DOI: 10.7717/peerj.4512

Genetic Evidence for the Convergent Evolution of Light Skin in Europeans and East Asians
journal, December 2006

  • Norton, H. L.; Kittles, R. A.; Parra, E.
  • Molecular Biology and Evolution, Vol. 24, Issue 3
  • DOI: 10.1093/molbev/msl203

Conservation and evolution of gene coexpression networks in human and chimpanzee brains
journal, November 2006

  • Oldham, M. C.; Horvath, S.; Geschwind, D. H.
  • Proceedings of the National Academy of Sciences, Vol. 103, Issue 47
  • DOI: 10.1073/pnas.0605938103

Variation in gene expression within and among natural populations
journal, September 2002

  • Oleksiak, Marjorie F.; Churchill, Gary A.; Crawford, Douglas L.
  • Nature Genetics, Vol. 32, Issue 2
  • DOI: 10.1038/ng983

Scavenger Receptor CD163 and Its Biological Functions
journal, January 2009

  • Onofre, Gabriela; Koláčková, Martina; Jankovičová, Karolína
  • Acta Medica (Hradec Kralove, Czech Republic), Vol. 52, Issue 2
  • DOI: 10.14712/18059694.2016.105

Towards the identification of the loci of adaptive evolution
journal, February 2015

  • Pardo-Diaz, Carolina; Salazar, Camilo; Jiggins, Chris D.
  • Methods in Ecology and Evolution, Vol. 6, Issue 4
  • DOI: 10.1111/2041-210X.12324

Snowflake Vitreoretinal Degeneration (SVD) Mutation R162W Provides New Insights into Kir7.1 Ion Channel Structure and Function
journal, August 2013

The evolutionary ecology of the major histocompatibility complex
journal, August 2005

Review and update of mutations causing Waardenburg syndrome
journal, February 2010

  • Pingault, Véronique; Ente, Dorothée; Dastot-Le Moal, Florence
  • Human Mutation, Vol. 31, Issue 4
  • DOI: 10.1002/humu.21211

NDUFA4 Mutations Underlie Dysfunction of a Cytochrome c Oxidase Subunit Linked to Human Neurological Disease
journal, June 2013

A Systems Genetics Approach Implicates USF1, FADS3, and Other Causal Candidate Genes for Familial Combined Hyperlipidemia
journal, September 2009

The genomic landscape underlying phenotypic integrity in the face of gene flow in crows
journal, June 2014

Transcriptomics of colour patterning and coloration shifts in crows
journal, September 2015

  • Poelstra, J. W.; Vijay, N.; Hoeppner, M. P.
  • Molecular Ecology, Vol. 24, Issue 18
  • DOI: 10.1111/mec.13353

Antibacterial Properties of the Mammalian L-Amino Acid Oxidase IL4I1
journal, January 2013

Autonomous regulation of the anaphase-promoting complex couples mitosis to S-phase entry
journal, November 2004

Transcriptional Analysis of Vitiligo Skin Reveals the Alteration of WNT Pathway: A Promising Target for Repigmenting Vitiligo Patients
journal, December 2015

  • Regazzetti, Claire; Joly, Florence; Marty, Carine
  • Journal of Investigative Dermatology, Vol. 135, Issue 12
  • DOI: 10.1038/jid.2015.335

g:Profiler—a web server for functional interpretation of gene lists (2011 update)
journal, June 2011

  • Reimand, Jüri; Arak, Tambet; Vilo, Jaak
  • Nucleic Acids Research, Vol. 39, Issue suppl_2
  • DOI: 10.1093/nar/gkr378

Pleiotropic effects of coat colour-associated mutations in humans, mice and other mammals
journal, June 2013

Autoimmunity as an aetiological factor in vitiligo
journal, August 2007

Innate immune mechanisms in vitiligo: danger from within
journal, December 2013

  • Richmond, Jillian M.; Frisoli, Michael L.; Harris, John E.
  • Current Opinion in Immunology, Vol. 25, Issue 6
  • DOI: 10.1016/j.coi.2013.10.010

Identification of the oncogenic kinase TOPK/PBK as a master mitotic regulator of C2H2 zinc finger proteins
journal, January 2015

Sexual selection in genetic colour-polymorphic species: a review of experimental studies and perspectives
journal, July 2006

Microphthalmia-Associated Transcription Factor in the Wnt Signaling Pathway
journal, June 2003

Functional compatibility between isoform   and   of type II DNA topoisomerase
journal, March 2004

Effect of the MC1R gene on sexual dimorphism in melanin-based colorations
journal, May 2015

  • San-Jose, Luis M.; Ducrest, Anne-Lyse; Ducret, Valérie
  • Molecular Ecology, Vol. 24, Issue 11
  • DOI: 10.1111/mec.13193

MC1R variants affect the expression of melanocortin and melanogenic genes and the association between melanocortin genes and coloration
journal, October 2016

  • San-Jose, Luis M.; Ducrest, Anne-Lyse; Ducret, Valérie
  • Molecular Ecology, Vol. 26, Issue 1
  • DOI: 10.1111/mec.13861

Genomics of coloration in natural animal populations
journal, May 2017

  • San-Jose, Luis M.; Roulin, Alexandre
  • Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 372, Issue 1724
  • DOI: 10.1098/rstb.2016.0337

Adaptive evolution of facial colour patterns in Neotropical primates
journal, January 2012

  • Santana, Sharlene E.; Lynch Alfaro, Jessica; Alfaro, Michael E.
  • Proceedings of the Royal Society B: Biological Sciences, Vol. 279, Issue 1736
  • DOI: 10.1098/rspb.2011.2326

The complement system
journal, September 2010

Signaling pathways in melanosome biogenesis and pathology
journal, July 2010

Genetic subdivision and candidate genes under selection in North American grey wolves
journal, November 2015

  • Schweizer, Rena M.; vonHoldt, Bridgett M.; Harrigan, Ryan
  • Molecular Ecology, Vol. 25, Issue 1
  • DOI: 10.1111/mec.13364

Inflammatory Proprotein Convertase-Matrix Metalloproteinase Proteolytic Pathway in Antigen-presenting Cells as a Step to Autoimmune Multiple Sclerosis
journal, September 2009

  • Shiryaev, Sergey A.; Remacle, Albert G.; Savinov, Alexei Y.
  • Journal of Biological Chemistry, Vol. 284, Issue 44
  • DOI: 10.1074/jbc.M109.041244

Neuroendocrine System of the Skin
journal, January 2005

Melanin Pigmentation in Mammalian Skin and Its Hormonal Regulation
journal, October 2004

  • Slominski, Andrzej; Tobin, Desmond J.; Shibahara, Shigeki
  • Physiological Reviews, Vol. 84, Issue 4
  • DOI: 10.1152/physrev.00044.2003

Six Decades of Vitiligo Genetics: Genome-Wide Studies Provide Insights into Autoimmune Pathogenesis
journal, February 2012

  • Spritz, Richard A.
  • Journal of Investigative Dermatology, Vol. 132, Issue 2
  • DOI: 10.1038/jid.2011.321

Modern vitiligo genetics sheds new light on an ancient disease
journal, May 2013

AMPK in Health and Disease
journal, July 2009

Statistical significance for genomewide studies
journal, July 2003

  • Storey, J. D.; Tibshirani, R.
  • Proceedings of the National Academy of Sciences, Vol. 100, Issue 16, p. 9440-9445
  • DOI: 10.1073/pnas.1530509100

Isolation, Characterization, and Mapping of Two Human Potassium Channels
journal, December 1997

  • Su, Kui; Kyaw, Hla; Fan, Ping
  • Biochemical and Biophysical Research Communications, Vol. 241, Issue 3
  • DOI: 10.1006/bbrc.1997.7830

Mouse Models for Four Types of Waardenburg Syndrome
journal, October 2003

The Genotype-Tissue Expression (GTEx) project
journal, May 2013

  • Lonsdale, John; Thomas, Jeffrey; Salvatore, Mike
  • Nature Genetics, Vol. 45, Issue 6
  • DOI: 10.1038/ng.2653

The power and promise of RNA-seq in ecology and evolution
journal, March 2016

  • Todd, Erica V.; Black, Michael A.; Gemmell, Neil J.
  • Molecular Ecology, Vol. 25, Issue 6
  • DOI: 10.1111/mec.13526

MHC Class II Polymorphisms, Autoreactive T-Cells, and Autoimmunity
journal, January 2013

Variations in MHC Class II Antigen Processing and Presentation in Health and Disease
journal, May 2016

Ecological genomics: understanding gene and genome function in the natural environment
journal, May 2007

Role of protein kinase C β 2 activation in TNF-α-induced human vascular endothelial cell apoptosis
journal, March 2009

  • Wang, Fang; Liu, Hui-min; Irwin, Michael G.
  • Canadian Journal of Physiology and Pharmacology, Vol. 87, Issue 3
  • DOI: 10.1139/Y09-004

Human Pigmentation and Environmental Adaptation
journal, November 1965

New insights into the roles of Stat5a/b and Stat3 in T cell development and differentiation
journal, August 2008

“Good Enough Solutions” and the Genetics of Complex Diseases
journal, August 2012

Developmental plasticity and the origin of species differences
journal, May 2005

  • West-Eberhard, M. J.
  • Proceedings of the National Academy of Sciences, Vol. 102, Issue Supplement 1
  • DOI: 10.1073/pnas.0501844102

Comparative genomics in ecological physiology: toward a more nuanced understanding of acclimation and adaptation
journal, February 2012

  • Whitehead, A.
  • Journal of Experimental Biology, Vol. 215, Issue 6
  • DOI: 10.1242/jeb.058735

TiSGeD: a database for tissue-specific genes
journal, March 2010

Physiological factors that regulate skin pigmentation
journal, March 2009

  • Yamaguchi, Yuji; Hearing, Vincent J.
  • BioFactors, Vol. 35, Issue 2
  • DOI: 10.1002/biof.29

SOX10, in combination with Sp1, regulates the endothelin receptor type B gene in human melanocyte lineage cells
journal, April 2006

Transcriptome Analysis Reveals Markers of Aberrantly Activated Innate Immunity in Vitiligo Lesional and Non-Lesional Skin
journal, December 2012

A General Framework for Weighted Gene Co-Expression Network Analysis
journal, January 2005

  • Zhang, Bin; Horvath, Steve
  • Statistical Applications in Genetics and Molecular Biology, Vol. 4, Issue 1
  • DOI: 10.2202/1544-6115.1128

CDK5RAP2 is required for spindle checkpoint function
journal, April 2009

  • Zhang, Xiaoying; Liu, Dongyun; Lv, Shuang
  • Cell Cycle, Vol. 8, Issue 8
  • DOI: 10.4161/cc.8.8.8205