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Title: Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA Cys and elongation factor SelB

Abstract

Not provided.

Authors:
ORCiD logo [1];  [1];  [2];  [1]; ORCiD logo [3]
  1. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA
  2. Department of Chemistry, Yale University, New Haven, CT, USA
  3. Department of Molecular Biophysics and Biochemistry, Yale University, New Haven, CT, USA; Department of Chemistry, Yale University, New Haven, CT, USA
Publication Date:
Research Org.:
Yale Univ., New Haven, CT (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1540367
DOE Contract Number:  
FG02-98ER20311
Resource Type:
Journal Article
Journal Name:
RNA Biology
Additional Journal Information:
Journal Volume: 15; Journal Issue: 4-5; Journal ID: ISSN 1547-6286
Publisher:
Taylor & Francis
Country of Publication:
United States
Language:
English
Subject:
Biochemistry & Molecular Biology

Citation Formats

Vargas-Rodriguez, Oscar, Englert, Markus, Merkuryev, Anna, Mukai, Takahito, and Söll, Dieter. Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA Cys and elongation factor SelB. United States: N. p., 2017. Web. doi:10.1080/15476286.2018.1474074.
Vargas-Rodriguez, Oscar, Englert, Markus, Merkuryev, Anna, Mukai, Takahito, & Söll, Dieter. Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA Cys and elongation factor SelB. United States. doi:10.1080/15476286.2018.1474074.
Vargas-Rodriguez, Oscar, Englert, Markus, Merkuryev, Anna, Mukai, Takahito, and Söll, Dieter. Thu . "Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA Cys and elongation factor SelB". United States. doi:10.1080/15476286.2018.1474074.
@article{osti_1540367,
title = {Recoding of the selenocysteine UGA codon by cysteine in the presence of a non-canonical tRNA Cys and elongation factor SelB},
author = {Vargas-Rodriguez, Oscar and Englert, Markus and Merkuryev, Anna and Mukai, Takahito and Söll, Dieter},
abstractNote = {Not provided.},
doi = {10.1080/15476286.2018.1474074},
journal = {RNA Biology},
issn = {1547-6286},
number = 4-5,
volume = 15,
place = {United States},
year = {2017},
month = {11}
}

Works referenced in this record:

Selenoproteins: Molecular Pathways and Physiological Roles
journal, July 2014

  • Labunskyy, Vyacheslav M.; Hatfield, Dolph L.; Gladyshev, Vadim N.
  • Physiological Reviews, Vol. 94, Issue 3
  • DOI: 10.1152/physrev.00039.2013

The pathway to GTPase activation of elongation factor SelB on the ribosome
journal, November 2016

  • Fischer, Niels; Neumann, Piotr; Bock, Lars V.
  • Nature, Vol. 540, Issue 7631, p. 80-85
  • DOI: 10.1038/nature20560

Ribosome dynamics during decoding
journal, March 2017

  • Rodnina, Marina V.; Fischer, Niels; Maracci, Cristina
  • Philosophical Transactions of the Royal Society B: Biological Sciences, Vol. 372, Issue 1716
  • DOI: 10.1098/rstb.2016.0182

Facile Recoding of Selenocysteine in Nature
journal, March 2016

  • Mukai, Takahito; Englert, Markus; Tripp, H. James
  • Angewandte Chemie International Edition, Vol. 55, Issue 17, p. 5337-5341
  • DOI: 10.1002/anie.201511657

Mutagenesis of selC , the gene for the selenocysteine-insertlng tRNA-species in E.coli : effects on in vivo function
journal, January 1990

  • Baron, Christian; Heider, Johann; Böck, August
  • Nucleic Acids Research, Vol. 18, Issue 23
  • DOI: 10.1093/nar/18.23.6761

Direct detection of potential selenium delivery proteins by using an Escherichia coli strain unable to incorporate selenium from selenite into proteins
journal, June 2002

  • Lacourciere, G. M.; Levine, R. L.; Stadtman, T. C.
  • Proceedings of the National Academy of Sciences, Vol. 99, Issue 14, p. 9150-9153
  • DOI: 10.1073/pnas.142291199

Cotranslational insertion of selenocysteine into formate dehydrogenase from Escherichia coli directed by a UGA codon.
journal, May 1987

  • Zinoni, F.; Birkmann, A.; Leinfelder, W.
  • Proceedings of the National Academy of Sciences, Vol. 84, Issue 10
  • DOI: 10.1073/pnas.84.10.3156

Catalytic properties of an Escherichia coli formate dehydrogenase mutant in which sulfur replaces selenium.
journal, October 1991

  • Axley, M. J.; Bock, A.; Stadtman, T. C.
  • Proceedings of the National Academy of Sciences, Vol. 88, Issue 19
  • DOI: 10.1073/pnas.88.19.8450

Recognition of tRNACys by Escherichia coli cysteinyl-tRNA synthetase
journal, July 1993

  • Komatsoulis, George A.; Abelson, John
  • Biochemistry, Vol. 32, Issue 29, p. 7435-7444
  • DOI: 10.1021/bi00080a014

Minimum information about a single amplified genome (MISAG) and a metagenome-assembled genome (MIMAG) of bacteria and archaea
journal, August 2017

  • Bowers, Robert M.; Kyrpides, Nikos C.; Stepanauskas, Ramunas
  • Nature Biotechnology, Vol. 35, Issue 8
  • DOI: 10.1038/nbt.3893

Global metagenomic survey reveals a new bacterial candidate phylum in geothermal springs
journal, January 2016

  • Eloe-Fadrosh, Emiley A.; Paez-Espino, David; Jarett, Jessica
  • Nature Communications, Vol. 7, Issue 1
  • DOI: 10.1038/ncomms10476

Metagenome sequencing and 98 microbial genomes from Juan de Fuca Ridge flank subsurface fluids
journal, March 2017

  • Jungbluth, Sean P.; Amend, Jan P.; Rappé, Michael S.
  • Scientific Data, Vol. 4, Issue 1
  • DOI: 10.1038/sdata.2017.37

Recovery of nearly 8,000 metagenome-assembled genomes substantially expands the tree of life
journal, September 2017

  • Parks, Donovan H.; Rinke, Christian; Chuvochina, Maria
  • Nature Microbiology, Vol. 2, Issue 11
  • DOI: 10.1038/s41564-017-0012-7

Computational identification of the selenocysteine tRNA (tRNASec) in genomes
journal, February 2017

  • Santesmasses, Didac; Mariotti, Marco; Guigó, Roderic
  • PLOS Computational Biology, Vol. 13, Issue 2, Article No. e1005383
  • DOI: 10.1371/journal.pcbi.1005383

Genetic Code Supports Targeted Insertion of Two Amino Acids by One Codon
journal, January 2009

  • Turanov, A. A.; Lobanov, A. V.; Fomenko, D. E.
  • Science, Vol. 323, Issue 5911, p. 259-261
  • DOI: 10.1126/science.1164748

Targeted insertion of cysteine by decoding UGA codons with mammalian selenocysteine machinery
journal, November 2010

  • Xu, X. -M.; Turanov, A. A.; Carlson, B. A.
  • Proceedings of the National Academy of Sciences, Vol. 107, Issue 50
  • DOI: 10.1073/pnas.1009947107

Regulation of Selenocysteine Content of Human Selenoprotein P by Dietary Selenium and Insertion of Cysteine in Place of Selenocysteine
journal, October 2015


Bacterial selenocysteine synthase. Structural and functional properties
journal, June 1998


Selenocysteine-independent suppression of UGA codons in the archaeon Methanococcus maripaludis
journal, November 2015

  • Seyhan, Deniz; Jehmlich, Nico; von Bergen, Martin
  • Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 1850, Issue 11
  • DOI: 10.1016/j.bbagen.2015.07.009

Wobble decoding by the Escherichia coli selenocysteine insertion machinery
journal, August 2013

  • Xu, J.; Croitoru, V.; Rutishauser, D.
  • Nucleic Acids Research, Vol. 41, Issue 21, p. 9800-9811
  • DOI: 10.1093/nar/gkt764

Effects of combinatorial expression of selA, selB and selC genes on the efficiency of selenocysteine incorporation in Escherichia coli
journal, January 2013

  • Xu, Ya-wei; Jiang, Zhi-hua; Mu, Ying
  • Chemical Research in Chinese Universities, Vol. 29, Issue 1
  • DOI: 10.1007/s40242-013-2250-4

Engineering the elongation factor Tu for efficient selenoprotein synthesis
journal, July 2014

  • Haruna, Ken-ichi; Alkazemi, Muhammad H.; Liu, Yuchen
  • Nucleic Acids Research, Vol. 42, Issue 15, p. 9976-9983
  • DOI: 10.1093/nar/gku691

Rewiring Translation for Elongation Factor Tu-Dependent Selenocysteine Incorporation
journal, November 2012

  • Aldag, Caroline; Bröcker, Markus J.; Hohn, Michael J.
  • Angewandte Chemie International Edition, Vol. 52, Issue 5, p. 1441-1445
  • DOI: 10.1002/anie.201207567

Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
journal, January 1984

  • Melton, D. A.; Krieg, P. A.; Rebagliati, M. R.
  • Nucleic Acids Research, Vol. 12, Issue 18
  • DOI: 10.1093/nar/12.18.7035

[3′-32P]-labeling tRNA with nucleotidyltransferase for assaying aminoacylation and peptide bond formation
journal, February 2008


Tertiary structure of bacterial selenocysteine tRNA
journal, May 2013

  • Itoh, Y.; Sekine, S.-i.; Suetsugu, S.
  • Nucleic Acids Research, Vol. 41, Issue 13, p. 6729-6738
  • DOI: 10.1093/nar/gkt321