Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate

Oslund, Rob C.; Su, Xiaoyang; Haugbro, Michael; Kee, Jung-Min; Esposito, Mark; David, Yael; Wang, Boyuan; Ge, Eva; Perlman, David H.; Kang, Yibin; Muir, Tom W.; Rabinowitz, Joshua D.

doi:10.1038/nchembio.2453

Title: Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate

Journal Article · Mon Aug 07 00:00:00 EDT 2017 · Nature Chemical Biology

DOI:https://doi.org/10.1038/nchembio.2453· OSTI ID:1539779

Oslund, Rob C.; Su, Xiaoyang; Haugbro, Michael;

; Esposito, Mark; David, Yael; Wang, Boyuan; Ge, Eva; Perlman, David H.; Kang, Yibin; Muir, Tom W.; Rabinowitz, Joshua D.

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Research Organization:: Princeton Univ., NJ (United States)

Sponsoring Organization:: USDOE Office of Science (SC)

DOE Contract Number:: SC0012461

OSTI ID:: 1539779

Journal Information:: Nature Chemical Biology, Vol. 13, Issue 10; ISSN 1552-4450

Publisher:: Nature Publishing Group

Country of Publication:: United States

Language:: English

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Phosphoglycerate mutase 1 in cancer: A promising target for diagnosis and therapy Sharif, Farzana; Rasul, Azhar; Ashraf, Asma IUBMB Life, Vol. 71, Issue 10 https://doi.org/10.1002/iub.2100	journal	June 2019
Antitumor and antiangiogenic activity of the novel chimeric inhibitor animacroxam in testicular germ cell cancer Steinemann, Gustav; Dittmer, Alexandra; Schmidt, Jacob Charité - Universitätsmedizin Berlin https://doi.org/10.17169/refubium-32284	text	January 2019
Antitumor and antiangiogenic activity of the novel chimeric inhibitor animacroxam in testicular germ cell cancer Steinemann, Gustav; Dittmer, Alexandra; Schmidt, Jacob Molecular Oncology, Vol. 13, Issue 12 https://doi.org/10.1002/1878-0261.12582	journal	September 2019
Proliferating tumor cells mimick glucose metabolism of mature human erythrocytes Ghashghaeinia, Mehrdad; Köberle, Martin; Mrowietz, Ulrich Cell Cycle, Vol. 18, Issue 12 https://doi.org/10.1080/15384101.2019.1618125	journal	May 2019
Integrated analysis of label-free quantitative proteomics and bioinformatics reveal insights into signaling pathways in male breast cancer Gomig, Talita Helen Bombardelli; Gontarski, Amanda Moletta; Cavalli, Iglenir João Genetics and Molecular Biology, Vol. 44, Issue 1 https://doi.org/10.1590/1678-4685-gmb-2019-0410	journal	January 2021
Serine synthesis through PHGDH coordinates nucleotide levels by maintaining central carbon metabolism Reid, Michael A.; Allen, Annamarie E.; Liu, Shiyu Nature Communications, Vol. 9, Issue 1 https://doi.org/10.1038/s41467-018-07868-6	journal	December 2018
Phosphoglycolate has profound metabolic effects but most likely no role in a metabolic DNA response in cancer cell lines Gerin, Isabelle; Bury, Marina; Baldin, Francesca Biochemical Journal, Vol. 476, Issue 4 https://doi.org/10.1042/bcj20180435	journal	February 2019
Identification of a Subtype of Hepatocellular Carcinoma with Poor Prognosis Based on Expression of Genes within the Glucose Metabolic Pathway Zhang, Xiaoli; Li, Jin; Ghoshal, Kalpana Cancers, Vol. 11, Issue 12 https://doi.org/10.3390/cancers11122023	journal	December 2019
Sickling-suppressive effects of chrysin may be associated with sequestration of deoxy-haemoglobin, 2,3-bisphosphoglycerate mutase, alteration of redox homeostasis and functional chemistry of sickle erythrocytes Muhammad, A.; Waziri, Ad; Forcados, Ge Human & Experimental Toxicology, Vol. 39, Issue 4 https://doi.org/10.1177/0960327119895815	journal	December 2019
Sickling-preventive effects of rutin is associated with modulation of deoxygenated haemoglobin, 2,3-bisphosphoglycerate mutase, redox status and alteration of functional chemistry in sickle erythrocytes Muhammad, Aliyu; Waziri, Aliyu Dahiru; Forcados, Gilead Ebiegberi Heliyon, Vol. 5, Issue 6 https://doi.org/10.1016/j.heliyon.2019.e01905	journal	June 2019
Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect Wiese, Elizabeth K.; Hitosugi, Taro Frontiers in Cell and Developmental Biology, Vol. 6 https://doi.org/10.3389/fcell.2018.00079	journal	July 2018

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