skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Identification of Carboxylate, Phosphate, and Phenoxide Functionalities in Deprotonated Molecules Related to Drug Metabolites via Ion–Molecule Reactions with water and Diethylhydroxyborane

Abstract

Not provided.

Authors:
; ; ; ;
Publication Date:
Research Org.:
Purdue Univ., West Lafayette, IN (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1537865
DOE Contract Number:  
SC0000997
Resource Type:
Journal Article
Journal Name:
Journal of the American Society for Mass Spectrometry
Additional Journal Information:
Journal Volume: 28; Journal Issue: 10; Journal ID: ISSN 1044-0305
Publisher:
American Society for Mass Spectrometry
Country of Publication:
United States
Language:
English
Subject:
Biochemistry & Molecular Biology; Chemistry; Spectroscopy

Citation Formats

Zhu, Hanyu, Ma, Xin, Kong, John Y., Zhang, Minli, and Kenttämaa, Hilkka I. Identification of Carboxylate, Phosphate, and Phenoxide Functionalities in Deprotonated Molecules Related to Drug Metabolites via Ion–Molecule Reactions with water and Diethylhydroxyborane. United States: N. p., 2017. Web. doi:10.1007/s13361-017-1713-0.
Zhu, Hanyu, Ma, Xin, Kong, John Y., Zhang, Minli, & Kenttämaa, Hilkka I. Identification of Carboxylate, Phosphate, and Phenoxide Functionalities in Deprotonated Molecules Related to Drug Metabolites via Ion–Molecule Reactions with water and Diethylhydroxyborane. United States. doi:10.1007/s13361-017-1713-0.
Zhu, Hanyu, Ma, Xin, Kong, John Y., Zhang, Minli, and Kenttämaa, Hilkka I. Mon . "Identification of Carboxylate, Phosphate, and Phenoxide Functionalities in Deprotonated Molecules Related to Drug Metabolites via Ion–Molecule Reactions with water and Diethylhydroxyborane". United States. doi:10.1007/s13361-017-1713-0.
@article{osti_1537865,
title = {Identification of Carboxylate, Phosphate, and Phenoxide Functionalities in Deprotonated Molecules Related to Drug Metabolites via Ion–Molecule Reactions with water and Diethylhydroxyborane},
author = {Zhu, Hanyu and Ma, Xin and Kong, John Y. and Zhang, Minli and Kenttämaa, Hilkka I.},
abstractNote = {Not provided.},
doi = {10.1007/s13361-017-1713-0},
journal = {Journal of the American Society for Mass Spectrometry},
issn = {1044-0305},
number = 10,
volume = 28,
place = {United States},
year = {2017},
month = {7}
}

Works referenced in this record:

Drug Metabolite Profiling and Identification by High-resolution Mass Spectrometry
journal, June 2011

  • Zhu, Mingshe; Zhang, Haiying; Humphreys, W. Griffith
  • Journal of Biological Chemistry, Vol. 286, Issue 29
  • DOI: 10.1074/jbc.R110.200055

Advances in structure elucidation of small molecules using mass spectrometry
journal, August 2010


Metabolite identification and quantitation in LC-MS/MS-based metabolomics
journal, February 2012


Special feature: Historical. Collision-induced dissociation: Readings and commentary
journal, September 1995


Diagnostic fragmentations of adducts formed between carbanions and carbon disulfide in the gas phase. A joint experimental and theoretical study
journal, January 2010

  • Maclean, Micheal J.; Walker, Scott; Wang, Tianfang
  • Org. Biomol. Chem., Vol. 8, Issue 2
  • DOI: 10.1039/B916477D

Analytical applications of ion-molecule reactions
journal, January 1997


Quadrupole ion trap studies of fundamental organic reactions
journal, January 2004


Mass Spectrometric Studies of Organic Ion/Molecule Reactions
journal, February 2001


Functional Group Selective Ion/Molecule Reactions:  Mass Spectrometric Identification of the Amido Functionality in Protonated Monofunctional Compounds
journal, April 2007

  • Campbell, Karinna M.; Watkins, Michael A.; Li, Sen
  • The Journal of Organic Chemistry, Vol. 72, Issue 9
  • DOI: 10.1021/jo0618223

Identification of the sulfoxide functionality in protonated analytes via ion/molecule reactions in linear quadrupole ion trap mass spectrometry
journal, January 2014

  • Sheng, Huaming; Williams, Peggy E.; Tang, Weijuan
  • The Analyst, Vol. 139, Issue 17
  • DOI: 10.1039/C4AN00677A

Identification of the Sulfone Functionality in Protonated Analytes via Ion/Molecule Reactions in a Linear Quadrupole Ion Trap Mass Spectrometer
journal, March 2014

  • Sheng, Huaming; Williams, Peggy E.; Tang, Weijuan
  • The Journal of Organic Chemistry, Vol. 79, Issue 7
  • DOI: 10.1021/jo402645a

Regioselective ion–molecule reactions for the mass spectrometric differentiation of protonated isomeric aromatic diamines
journal, January 2008

  • Fu, Mingkun; Duan, Penggao; Li, Sen
  • The Analyst, Vol. 133, Issue 4
  • DOI: 10.1039/b801961d

Investigation of ion/molecule reactions as a quantification method for phosphorylated positional isomers: An FT-ICR approach
journal, August 2003

  • Gao, Hong; Petzold, Christopher J.; Leavell, Michael D.
  • Journal of the American Society for Mass Spectrometry, Vol. 14, Issue 8
  • DOI: 10.1016/S1044-0305(03)00401-X

Coupling of ion-molecule reactions with liquid chromatography on a quadrupole ion trap mass spectrometer
journal, January 2008

  • Pyatkivskyy, Yuriy; Ryzhov, Victor
  • Rapid Communications in Mass Spectrometry, Vol. 22, Issue 8
  • DOI: 10.1002/rcm.3494

Identification of the Phenol Functionality in Deprotonated Monomeric and Dimeric Lignin Degradation Products via Tandem Mass Spectrometry Based on Ion–Molecule Reactions with Diethylmethoxyborane
journal, August 2016

  • Zhu, Hanyu; Max, Joann P.; Marcum, Christopher L.
  • Journal of The American Society for Mass Spectrometry, Vol. 27, Issue 11
  • DOI: 10.1007/s13361-016-1442-9

Choosing between Atmospheric Pressure Chemical Ionization and Electrospray Ionization Interfaces for the HPLC/MS Analysis of Pesticides
journal, November 2001

  • Thurman, E. M.; Ferrer, Imma; Barceló, Damia
  • Analytical Chemistry, Vol. 73, Issue 22
  • DOI: 10.1021/ac010506f

Utilisation of Gas-Phase Ion—Molecule Reactions for Differentiation between Phospho- and Sulfocarbohydrates
journal, April 2014

  • Piatkivskyi, Andrii; Pyatkivskyy, Yuriy; Hurt, Matt
  • European Journal of Mass Spectrometry, Vol. 20, Issue 2
  • DOI: 10.1255/ejms.1270

Gas phase reactions of trimethyl borate with phosphates and their non-covalent complexes
journal, September 2002

  • Gronert, Scott; O’Hair, Richard A. J.
  • Journal of the American Society for Mass Spectrometry, Vol. 13, Issue 9
  • DOI: 10.1016/S1044-0305(02)00424-5

Estimation of effective ion temperatures in a quadrupole ion trap
journal, August 1998


Hydrogen-bonding energies to negative ions from gas-phase measurements of ionic equilibriums
journal, December 1971

  • Yamdagni, R.; Kebarle, P.
  • Journal of the American Chemical Society, Vol. 93, Issue 26
  • DOI: 10.1021/ja00755a003