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Modulation of saturation and chain length of fatty acids in Saccharomyces cerevisiae for production of cocoa butter-like lipids

Journal Article · · Biotechnology and Bioengineering
DOI:https://doi.org/10.1002/bit.26518· OSTI ID:1537506
 [1];  [1];  [1];  [1];  [2]
  1. Department of Biology and Biological EngineeringChalmers University of TechnologyGothenburgSweden; Novo Nordisk Foundation Center for BiosustainabilityChalmers University of TechnologyGothenburgSweden
  2. Department of Biology and Biological EngineeringChalmers University of TechnologyGothenburgSweden; Novo Nordisk Foundation Center for BiosustainabilityChalmers University of TechnologyGothenburgSweden; Novo Nordisk Foundation Center for BiosustainabilityTechnical University of DenmarkLyngbyDenmark

Not provided.

Research Organization:
Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)
Sponsoring Organization:
USDOE Office of Science (SC)
DOE Contract Number:
SC0008744
OSTI ID:
1537506
Journal Information:
Biotechnology and Bioengineering, Vol. 115, Issue 4; ISSN 0006-3592
Publisher:
Wiley
Country of Publication:
United States
Language:
English

References (39)

ELO2 and ELO3 , Homologues of the Saccharomyces cerevisiae ELO1 Gene, Function in Fatty Acid Elongation and Are Required for Sphingolipid Formation July 1997
Characterization of different promoters for designing a new expression vector in Saccharomyces cerevisiae November 2010
TAG composition and solid fat content of palm oil, sunflower oil, and palm kernel olein belends before and after chemical interesterification November 2002
Die Synthese verschiedener Carbonsauren durch den Multienzymkomplex der Fettsauresynthese aus Hefe und die Erklarung ihrer Bildung September 1969
Acetyl CoA Carboxylase Shares Control of Fatty Acid Synthesis with Fatty Acid Synthase in Bovine Mammary Homogenate July 2006
Induction of stearoyl-CoA desaturase protects human arterial endothelial cells against lipotoxicity August 2008
Acetyl-CoA carboxylase exerts strong flux control over lipid synthesis in plants January 1994
Regulation of Gene Expression through a Transcriptional Repressor that Senses Acyl-Chain Length in Membrane Phospholipids June 2014
Review of cocoa butter and alternative fats for use in chocolate—Part A. Compositional data May 1998
Regulation of lipid accumulation in oleaginous micro-organisms November 2002
The yeast acyltransferase Sct1p regulates fatty acid desaturation by competing with the desaturase Ole1p April 2012
Fast and accurate preparation fatty acid methyl esters by microwave-assisted derivatization in the yeast Saccharomyces cerevisiae May 2012
Translocation of Phosphatidylthreonine and -serine to Mitochondria Diminishes Exponentially with Increasing Molecular Hydrophobicity May 2002
DGA1 (diacylglycerol acyltransferase gene) overexpression and leucine biosynthesis significantly increase lipid accumulation in the Δsnf2 disruptant of Saccharomyces cerevisiae November 2007
Elo1p-Dependent Carboxy-Terminal Elongation of C14:1Delta 9 to C16:1Delta 11 Fatty Acids in Saccharomyces cerevisiae July 2000
Liquid Chromatography-Mass Spectrometry (LC-MS)-Based Lipidomics for Studies of Body Fluids and Tissues December 2010
Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry January 2009
Improving polyketide and fatty acid synthesis by engineering of the yeast acetyl-CoA carboxylase October 2014
Production of fatty acid-derived oleochemicals and biofuels by synthetic yeast cell factories May 2016
Isolation and Characterization of a Gene Affecting Fatty Acid Elongation in Saccharomyces cerevisiae August 1996
Improving Production of Malonyl Coenzyme A-Derived Metabolites by Abolishing Snf1-Dependent Regulation of Acc1 May 2014
The DGA1 Gene Determines a Second Triglyceride Synthetic Pathway in Yeast December 2001
Structure Determinants for the Substrate Specificity of Acyl-CoA Δ9 Desaturases from a Marine Copepod January 2014
Flexibility of a Eukaryotic Lipidome – Insights from Yeast Lipidomics April 2012
Characterization of the methyltransferases in the yeast phosphatidylethanolamine methylation pathway by selective gene disruption November 1989
Lipid and hardness characteristics of cocoa butters from different geographic regions December 1989
Regional Variation in Shea Butter Lipid and Triterpene Composition in Four African Countries September 2005
Engineering lipid overproduction in the oleaginous yeast Yarrowia lipolytica May 2015
Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals January 2014
PGC-1α Coordinates Mitochondrial Respiratory Capacity and Muscular Fatty Acid Uptake via Regulation of VEGF-B January 2016
Changes in fatty-acid composition and stearoyl-acyl carrier protein desaturase expression in developing Theobroma cacao L. embryos March 1994
Reducing VEGF-B Signaling Ameliorates Renal Lipotoxicity and Protects against Diabetic Kidney Disease March 2017
Composition of Genuine Cocoa Butter and Cocoa Butter Equivalents August 2001
Improving biodiesel fuel properties by modifying fatty ester composition January 2009
Selection of oleaginous yeasts for fatty acid production May 2016
Rapid Quantification of Yeast Lipid using Microwave-Assisted Total Lipid Extraction and HPLC-CAD May 2013
Functional overexpression and characterization of lipogenesis-related genes in the oleaginous yeast Yarrowia lipolytica February 2016
Modification of selected indian vegetable fats into cocoa butter substitutes by lipase-catalyzed ester interchange October 1991
Increasing cocoa butter-like lipid production of Saccharomyces cerevisiae by expression of selected cocoa genes February 2017