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Title: Localization of RNS2 ribonuclease to the vacuole is required for its role in cellular homeostasis


Not provided.

; ; ; ;
Publication Date:
Research Org.:
Iowa State Univ., Ames, IA (United States)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
DOE Contract Number:  
Resource Type:
Journal Article
Journal Name:
Additional Journal Information:
Journal Volume: 245; Journal Issue: 4; Journal ID: ISSN 0032-0935
Country of Publication:
United States
Plant Sciences

Citation Formats

Floyd, Brice E., Mugume, Yosia, Morriss, Stephanie C., MacIntosh, Gustavo C., and Bassham, Diane C. Localization of RNS2 ribonuclease to the vacuole is required for its role in cellular homeostasis. United States: N. p., 2016. Web. doi:10.1007/s00425-016-2644-x.
Floyd, Brice E., Mugume, Yosia, Morriss, Stephanie C., MacIntosh, Gustavo C., & Bassham, Diane C. Localization of RNS2 ribonuclease to the vacuole is required for its role in cellular homeostasis. United States. doi:10.1007/s00425-016-2644-x.
Floyd, Brice E., Mugume, Yosia, Morriss, Stephanie C., MacIntosh, Gustavo C., and Bassham, Diane C. Mon . "Localization of RNS2 ribonuclease to the vacuole is required for its role in cellular homeostasis". United States. doi:10.1007/s00425-016-2644-x.
title = {Localization of RNS2 ribonuclease to the vacuole is required for its role in cellular homeostasis},
author = {Floyd, Brice E. and Mugume, Yosia and Morriss, Stephanie C. and MacIntosh, Gustavo C. and Bassham, Diane C.},
abstractNote = {Not provided.},
doi = {10.1007/s00425-016-2644-x},
journal = {Planta},
issn = {0032-0935},
number = 4,
volume = 245,
place = {United States},
year = {2016},
month = {12}

Works referenced in this record:

The Plant Vacuolar Sorting Receptor Atelp Is Involved in Transport of Nh 2 -Terminal Propeptide-Containing Vacuolar Proteins in Arabidopsis thaliana
journal, June 2000

  • Ahmed, Sharif U.; Rojo, Enrique; Kovaleva, Valentina
  • The Journal of Cell Biology, Vol. 149, Issue 7
  • DOI: 10.1083/jcb.149.7.1335

Several RNase T2 enzymes function in induced tRNA and rRNA turnover in the ciliate Tetrahymena
journal, January 2012

  • Andersen, Kasper L.; Collins, Kathleen
  • Molecular Biology of the Cell, Vol. 23, Issue 1
  • DOI: 10.1091/mbc.E11-08-0689

Take the “A” tail – quality control of ribosomal and transfer RNA
journal, September 2008

  • Andersen, K.; Jensen, T.; Brodersen, D.
  • Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, Vol. 1779, Issue 9
  • DOI: 10.1016/j.bbagrm.2008.06.011

Polysomes, P bodies and stress granules: states and fates of eukaryotic mRNAs
journal, June 2009

The Arabidopsis ribonuclease gene RNS1 is tightly controlled in response to phosphate limitation
journal, November 1994

Regulation of S-Like Ribonuclease Levels in Arabidopsis. Antisense Inhibition of RNS1 or RNS2 Elevates Anthocyanin Accumulation
journal, January 1999

  • Bariola, Pauline A.; MacIntosh, Gustavo C.; Green, Pamela J.
  • Plant Physiology, Vol. 119, Issue 1
  • DOI: 10.1104/pp.119.1.331

A carboxyl-terminal propeptide is necessary for proper sorting of barley lectin to vacuoles of tobacco.
journal, December 1990

  • Bednarek, S. Y.; Wilkins, T. A.; Dombrowski, J. E.
  • The Plant Cell, Vol. 2, Issue 12
  • DOI: 10.1105/tpc.2.12.1145

The Vegetative Vacuole Proteome of Arabidopsis thaliana Reveals Predicted and Unexpected Proteins
journal, November 2004

A novel C‐terminal sequence from barley polyamine oxidase is a vacuolar sorting signal
journal, September 2004

Floral dip: a simplified method for Agrobacterium-mediated transformation of Arabidopsis thaliana
journal, December 1998

The phylogenetic distribution of bacterial ribonucleases
journal, December 2002

Vacuolar H + -ATPase Activity Is Required for Endocytic and Secretory Trafficking in Arabidopsis
journal, February 2006

  • Dettmer, Jan; Hong-Hermesdorf, Anne; Stierhof, York-Dieter
  • The Plant Cell, Vol. 18, Issue 3
  • DOI: 10.1105/tpc.105.037978

Inhibitory effect of modified bafilomycins and concanamycins on P- and V-type adenosinetriphosphatases
journal, April 1993

  • Droese, Stefan; Bindseil, Kai U.; Bowman, Emma J.
  • Biochemistry, Vol. 32, Issue 15
  • DOI: 10.1021/bi00066a008

The RNase a superfamily: Generation of diversity and innate host defense
journal, September 2006

The FLAG™ peptide, a versatile fusion tag for the purification of recombinant proteins
journal, October 2001

What to Eat: Evidence for Selective Autophagy in Plants
journal, October 2012

Evidence for autophagy-dependent pathways of rRNA turnover in Arabidopsis
journal, December 2015

The Adaptor Complex AP-4 Regulates Vacuolar Protein Sorting at the trans-Golgi Network by Interacting with VACUOLAR SORTING RECEPTOR1
journal, November 2015

  • Fuji, Kentaro; Shirakawa, Makoto; Shimono, Yuki
  • Plant Physiology, Vol. 170, Issue 1
  • DOI: 10.1104/pp.15.00869

Leaf Senescence and Starvation-Induced Chlorosis Are Accelerated by the Disruption of an Arabidopsis Autophagy Gene
journal, July 2002

  • Hanaoka, Hideki; Noda, Takeshi; Shirano, Yumiko
  • Plant Physiology, Vol. 129, Issue 3
  • DOI: 10.1104/pp.011024

rnaset2 mutant zebrafish model familial cystic leukoencephalopathy and reveal a role for RNase T2 in degrading ribosomal RNA
journal, January 2011

  • Haud, N.; Kara, F.; Diekmann, S.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 3
  • DOI: 10.1073/pnas.1009811107

RNASET2-deficient cystic leukoencephalopathy resembles congenital cytomegalovirus brain infection
journal, June 2009

  • Henneke, Marco; Diekmann, Simone; Ohlenbusch, Andreas
  • Nature Genetics, Vol. 41, Issue 7
  • DOI: 10.1038/ng.398

Zebrafish RNase T2 genes and the evolution of secretory ribonucleases in animals
journal, January 2009

  • Hillwig, Melissa S.; Rizhsky, Ludmila; Wang, Ying
  • BMC Evolutionary Biology, Vol. 9, Issue 1
  • DOI: 10.1186/1471-2148-9-170

RNS2, a conserved member of the RNase T2 family, is necessary for ribosomal RNA decay in plants
journal, January 2011

  • Hillwig, M. S.; Contento, A. L.; Meyer, A.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 3
  • DOI: 10.1073/pnas.1009809108

The Many Pathways of RNA Degradation
journal, February 2009

Biochemical Models for S-RNase-Based Self-Incompatibility
journal, July 2008

  • Hua, Zhi-Hua; Fields, Allison; Kao, Teh-hui
  • Molecular Plant, Vol. 1, Issue 4
  • DOI: 10.1093/mp/ssn032

Bulk RNA degradation by nitrogen starvation‐induced autophagy in yeast
journal, December 2014

  • Huang, Hanghang; Kawamata, Tomoko; Horie, Tetsuro
  • The EMBO Journal, Vol. 34, Issue 2
  • DOI: 10.15252/embj.201489083

A Tobacco S-like RNase Inhibits Hyphal Elongation of Plant Pathogens
journal, March 2002

  • Hugot, Karine; Ponchet, Michel; Marais, Antoine
  • Molecular Plant-Microbe Interactions, Vol. 15, Issue 3
  • DOI: 10.1094/mpmi.2002.15.3.243

Evolutionary relationships among self-incompatibility RNases
journal, November 2001

  • Igic, B.; Kohn, J. R.
  • Proceedings of the National Academy of Sciences, Vol. 98, Issue 23
  • DOI: 10.1073/pnas.231386798

Structure-Function Relationships of Acid Ribonucleases
journal, February 1999

Amino acid sequence of an extracellular, phosphate-starvation-induced ribonuclease from cultured tomato (Lycopersicon esculentum) cells
journal, May 1991

Trafficking of Vacuolar Proteins: The Crucial Role of Arabidopsis Vacuolar Protein Sorting 29 in Recycling Vacuolar Sorting Receptor
journal, December 2012

  • Kang, Hyangju; Kim, Soo Youn; Song, Kyungyoung
  • The Plant Cell, Vol. 24, Issue 12
  • DOI: 10.1105/tpc.112.103481

The Solanum lycopersicum RNaseLER is a class II enzyme of the RNase T2 family and shows preferential expression in guard cells
journal, May 2011

Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
journal, April 2008

  • Kraft, Claudine; Deplazes, Anna; Sohrmann, Marc
  • Nature Cell Biology, Vol. 10, Issue 5
  • DOI: 10.1038/ncb1723

Molecular Cloning of cDNAs Encoding Ribonuclease-related Proteins in Nicotiana glutinosa Leaves, as Induced in Response to Wounding or to TMV-infection
journal, January 2002

  • Kurata, Naomi; Kariu, Tohru; Kawano, Shin
  • Bioscience, Biotechnology, and Biochemistry, Vol. 66, Issue 2
  • DOI: 10.1271/bbb.66.391

Degradation of the Endoplasmic Reticulum by Autophagy during Endoplasmic Reticulum Stress in Arabidopsis
journal, November 2012

Phosphate-Regulated Induction of Intracellular Ribonucleases in Cultured Tomato ( Lycopersicon esculentum ) Cells
journal, April 1992

  • Löffler, Andreas; Abel, Steffen; Jost, Wolfgang
  • Plant Physiology, Vol. 98, Issue 4
  • DOI: 10.1104/pp.98.4.1472

Characterization of Rny1, the Saccharomyces cerevisiae member of the T2 RNase family of RNases: Unexpected functions for ancient enzymes?
journal, January 2001

  • MacIntosh, G. C.; Bariola, P. A.; Newbigin, E.
  • Proceedings of the National Academy of Sciences, Vol. 98, Issue 3
  • DOI: 10.1073/pnas.98.3.1018

RNase T2 genes from rice and the evolution of secretory ribonucleases in plants
journal, February 2010

  • MacIntosh, Gustavo C.; Hillwig, Melissa S.; Meyer, Alexander
  • Molecular Genetics and Genomics, Vol. 283, Issue 4
  • DOI: 10.1007/s00438-010-0524-9

An Endoplasmic Reticulum-Derived Structure That Is Induced under Stress Conditions in Arabidopsis
journal, December 2002

  • Matsushima, Ryo; Hayashi, Yasuko; Kondo, Maki
  • Plant Physiology, Vol. 130, Issue 4
  • DOI: 10.1104/pp.009464

S-RNase-based self-incompatibility in Petunia inflata
journal, December 2010

  • Meng, Xiaoying; Sun, Penglin; Kao, Teh-hui
  • Annals of Botany, Vol. 108, Issue 4
  • DOI: 10.1093/aob/mcq253

ER bodies in plants of the Brassicales order: biogenesis and association with innate immunity
journal, March 2014

  • Nakano, Ryohei T.; Yamada, Kenji; Bednarek, PaweÅ‚
  • Frontiers in Plant Science, Vol. 5
  • DOI: 10.3389/fpls.2014.00073

A short C-terminal sequence is necessary and sufficient for the targeting of chitinases to the plant vacuole.
journal, November 1991

  • Neuhaus, J. M.; Sticher, L.; Meins, F.
  • Proceedings of the National Academy of Sciences, Vol. 88, Issue 22
  • DOI: 10.1073/pnas.88.22.10362

Sorting of plant vacuolar proteins is initiated in the ER: Vacuolar protein sorting
journal, February 2010

Retromer recycles vacuolar sorting receptors from the trans -Golgi network
journal, January 2010

Apg9p/Cvt7p Is an Integral Membrane Protein Required for Transport Vesicle Formation in the Cvt and Autophagy Pathways
journal, February 2000

  • Noda, Takeshi; Kim, John; Huang, Wei-Pang
  • The Journal of Cell Biology, Vol. 148, Issue 3
  • DOI: 10.1083/jcb.148.3.465

An S-like ribonuclease gene is used to generate a trap-leaf enzyme in the carnivorous plant Drosera adelae
journal, October 2005

SignalP 4.0: discriminating signal peptides from transmembrane regions
journal, September 2011

  • Petersen, Thomas Nordahl; Brunak, Søren; von Heijne, Gunnar
  • Nature Methods, Vol. 8, Issue 10
  • DOI: 10.1038/nmeth.1701

Isolation of intact vacuoles from Arabidopsis rosette leaf–derived protoplasts
journal, February 2007

  • Robert, Stéphanie; Zouhar, Jan; Carter, Clay
  • Nature Protocols, Vol. 2, Issue 2
  • DOI: 10.1038/nprot.2007.26

A putative vacuolar cargo receptor partially colocalizes with AtPEP12p on a prevacuolar compartment in Arabidopsis roots
journal, August 1998

  • Sanderfoot, A. A.; Ahmed, S. U.; Marty-Mazars, D.
  • Proceedings of the National Academy of Sciences, Vol. 95, Issue 17
  • DOI: 10.1073/pnas.95.17.9920

Interactions between Syntaxins Identify at Least Five SNARE Complexes within the Golgi/Prevacuolar System of the Arabidopsis Cell
journal, December 2001

  • Sanderfoot, Anton A.; Kovaleva, Valya; Bassham, Diane C.
  • Molecular Biology of the Cell, Vol. 12, Issue 12
  • DOI: 10.1091/mbc.12.12.3733

The C-terminal sequence from common bugle leaf galactan:galactan galactosyltransferase is a non-sequence-specific vacuolar sorting determinant
journal, April 2007

Genes with Homology to Fungal and S-Gene RNases Are Expressed in Arabidopsis thaliana
journal, July 1991

  • Taylor, Crispin B.; Green, Pamela J.
  • Plant Physiology, Vol. 96, Issue 3
  • DOI: 10.1104/pp.96.3.980

RNS2: a senescence-associated RNase of Arabidopsis that diverged from the S-RNases before speciation.
journal, June 1993

  • Taylor, C. B.; Bariola, P. A.; delCardayre, S. B.
  • Proceedings of the National Academy of Sciences, Vol. 90, Issue 11
  • DOI: 10.1073/pnas.90.11.5118

New insights into the function of Atg9
journal, January 2010

Atg9 vesicles are an important membrane source during early steps of autophagosome formation
journal, July 2012

  • Yamamoto, Hayashi; Kakuta, Soichiro; Watanabe, Tomonobu M.
  • The Journal of Cell Biology, Vol. 198, Issue 2
  • DOI: 10.1083/jcb.201202061

Isolation and characterization of cDNAs encoding xylogenesis-associated and wounding-induced ribonucleases in Zinnia elegans
journal, February 1996

  • Ye, Zheng-Hua; Droste, Donna L.
  • Plant Molecular Biology, Vol. 30, Issue 4
  • DOI: 10.1007/BF00019005

Identification and Properties of the Major Ribonucleases of Arabidopsis thaliana
journal, December 1991