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Title: Activation of CO2 by Vanadium Nitrogenase

Abstract

The reduction of CO2 into useful products, including hydrocarbon fuels, is an ongoing area of especial interest due to efforts to mitigate buildup of this greenhouse gas. While the industrial Fischer–Tropsch process can facilitate the hydrogenation of CO2 with H2 to form short-chain hydrocarbon products under high temperatures and pressures, a desire to perform these reactions under ambient conditions has inspired the use of biological approaches. Particularly, enzymes offer insight into how to activate and reduce CO2, but only one enzyme, nitrogenase, can perform the multielectron, multiproton reduction of CO2 into hydrocarbons. The vanadium-containing variant, V-nitrogenase, displays especial reactivity towards the hydrogenation of CO and CO2. This Focus Review discusses recent progress towards the activation and reduction of CO2 with three primary V-nitrogenase systems. These systems span both ATP-dependent and ATP-independent processes and utilize approaches with whole cells, isolated proteins, and extracted cofactors.

Authors:
 [1];  [1];  [1]
  1. Univ. of California, Irvine, CA (United States)
Publication Date:
Research Org.:
Univ. of California, Irvine, CA (United States)
Sponsoring Org.:
National Science Foundation (NSF); USDOE Office of Science (SC), Basic Energy Sciences (BES)
OSTI Identifier:
1533119
Alternate Identifier(s):
OSTI ID: 1375480
Grant/Contract Number:  
SC0014470; CHE-1609553
Resource Type:
Journal Article: Accepted Manuscript
Journal Name:
Chemistry - An Asian Journal
Additional Journal Information:
Journal Volume: 12; Journal Issue: 16; Journal ID: ISSN 1861-4728
Publisher:
Wiley
Country of Publication:
United States
Language:
English
Subject:
37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY; chemistry; ATP-independent; CO2; nitrogenase; reduction; vanadium

Citation Formats

Sickerman, Nathaniel S., Hu, Yilin, and Ribbe, Markus W. Activation of CO2 by Vanadium Nitrogenase. United States: N. p., 2017. Web. doi:10.1002/asia.201700624.
Sickerman, Nathaniel S., Hu, Yilin, & Ribbe, Markus W. Activation of CO2 by Vanadium Nitrogenase. United States. https://doi.org/10.1002/asia.201700624
Sickerman, Nathaniel S., Hu, Yilin, and Ribbe, Markus W. 2017. "Activation of CO2 by Vanadium Nitrogenase". United States. https://doi.org/10.1002/asia.201700624. https://www.osti.gov/servlets/purl/1533119.
@article{osti_1533119,
title = {Activation of CO2 by Vanadium Nitrogenase},
author = {Sickerman, Nathaniel S. and Hu, Yilin and Ribbe, Markus W.},
abstractNote = {The reduction of CO2 into useful products, including hydrocarbon fuels, is an ongoing area of especial interest due to efforts to mitigate buildup of this greenhouse gas. While the industrial Fischer–Tropsch process can facilitate the hydrogenation of CO2 with H2 to form short-chain hydrocarbon products under high temperatures and pressures, a desire to perform these reactions under ambient conditions has inspired the use of biological approaches. Particularly, enzymes offer insight into how to activate and reduce CO2, but only one enzyme, nitrogenase, can perform the multielectron, multiproton reduction of CO2 into hydrocarbons. The vanadium-containing variant, V-nitrogenase, displays especial reactivity towards the hydrogenation of CO and CO2. This Focus Review discusses recent progress towards the activation and reduction of CO2 with three primary V-nitrogenase systems. These systems span both ATP-dependent and ATP-independent processes and utilize approaches with whole cells, isolated proteins, and extracted cofactors.},
doi = {10.1002/asia.201700624},
url = {https://www.osti.gov/biblio/1533119}, journal = {Chemistry - An Asian Journal},
issn = {1861-4728},
number = 16,
volume = 12,
place = {United States},
year = {Mon May 22 00:00:00 EDT 2017},
month = {Mon May 22 00:00:00 EDT 2017}
}

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Cited by: 20 works
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Works referenced in this record:

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Works referencing / citing this record:

A Comparative Analysis of the CO-Reducing Activities of MoFe Proteins Containing Mo- and V-Nitrogenase Cofactors
journal, February 2018


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