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Title: Methods for making and processing metal targets for producing Cu-67 radioisotope for medical applications

Patent ·
OSTI ID:1531870
;

The present invention provides a method for producing Cu67 radioisotope suitable for use in medical applications. The method comprises irradiating a metallic zinc-68 (Zn68) target with a high energy gamma ray beam. After irradiation, the Cu67 is isolated from the Zn68 by any suitable method (e.g., chemical and/or physical separation). In a preferred embodiment, the Cu67 is isolated by sublimation of the zinc (e.g., at about 500-700° C. under reduced pressure) to afford a copper residue containing Cu67. The Cu67 can be further purified by chemical means (i.e., dissolution in acid, followed by ion exchange).

Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC02-06CH11357; W-31-109-ENG-38
Assignee:
UChicago Argonne, LLC (Chicago, IL)
Patent Number(s):
8,526,561
Application Number:
12/462,099
OSTI ID:
1531870
Resource Relation:
Patent File Date: 2009-07-29
Country of Publication:
United States
Language:
English

References (12)

Production of radioisotopes with a high specific activity by isotopic conversion patent September 1999
Production of high specific activity copper-67 patent-application January 2003
Process for extraction of metals from ores or industrial materials patent-application February 2006
Separation Metals patent December 1968
Production of no-carrier added 67Cu
  • Mirzadeh, S.; Mausner, L. F.; Srivastava, S. C.
  • International Journal of Radiation Applications and Instrumentation. Part A. Applied Radiation and Isotopes, Vol. 37, Issue 1, p. 29-36 https://doi.org/10.1016/0883-2889(86)90192-9
journal January 1986
Production of radioisotopes with a high specific activity by isotopic conversion patent March 2001
Polymer beads containing an immobilized extractant for sorbing metals from solution patent January 1994
The production of copper 67 from natural zinc using a linear accelerator journal November 1970
The Preparation of High Specific Activity Copper 64 journal January 1964
Electron Acceleration beyond 200 MeV in Underdense Plasmas using Table Top Laser Systems conference January 2002
Method of producing molybdenum-99 patent July 1998
Chemical modification of silica surface by immobilization of functional groups for extractive concentration of metal ions journal April 2004

Cited By (1)

Production of copper-67 from an enriched zinc-68 target patent June 2018

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62 RADIOLOGY AND NUCLEAR MEDICINE
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