Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae

Dolgova, Natalia V.; Nehzati, Susan; MacDonald, Tracy C.; Summers, Kelly L.; Crawford, Andrew M.; Krone, Patrick H.; George, Graham N.; Pickering, Ingrid J.

doi:10.1039/C8MT00315G

Title: Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae

Journal Article · Tue Jan 01 00:00:00 EST 2019 · Metallomics

DOI:https://doi.org/10.1039/C8MT00315G· OSTI ID:1504961

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^[1]; MacDonald, Tracy C. ^[1];

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^[1]; Krone, Patrick H. ^[3];

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Molecular and Environment Sciences Group, Department of Geological Sciences, University of Saskatchewan; Saskatoon; Canada
Department of Chemistry, University of Saskatchewan; Saskatoon; Canada
Department of Anatomy and Cell Biology, University of Saskatchewan; Saskatoon; Canada
Molecular and Environment Sciences Group, Department of Geological Sciences, University of Saskatchewan; Saskatoon; Canada; Department of Chemistry, University of Saskatchewan; Saskatoon

Mercury blocks selenium transport into and out of cells, disrupting selenoprotein function and preventing synthesis of new selenoproteins and compounds.

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Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: USDOE Office of Science (SC)

OSTI ID:: 1504961

Journal Information:: Metallomics, Vol. 11, Issue 3; ISSN 1756-5901

Publisher:: Royal Society of Chemistry

Country of Publication:: United States

Language:: ENGLISH

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