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Title: Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae

Abstract

Mercury blocks selenium transport into and out of cells, disrupting selenoprotein function and preventing synthesis of new selenoproteins and compounds.

Authors:
ORCiD logo [1]; ORCiD logo [1];  [1]; ORCiD logo [2]; ORCiD logo [1];  [3]; ORCiD logo [4]; ORCiD logo [4]
  1. Molecular and Environment Sciences Group, Department of Geological Sciences, University of Saskatchewan; Saskatoon; Canada
  2. Department of Chemistry, University of Saskatchewan; Saskatoon; Canada
  3. Department of Anatomy and Cell Biology, University of Saskatchewan; Saskatoon; Canada
  4. Molecular and Environment Sciences Group, Department of Geological Sciences, University of Saskatchewan; Saskatoon; Canada; Department of Chemistry, University of Saskatchewan; Saskatoon
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
1504961
Resource Type:
Journal Article
Journal Name:
Metallomics
Additional Journal Information:
Journal Volume: 11; Journal Issue: 3; Journal ID: ISSN 1756-5901
Publisher:
Royal Society of Chemistry
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Dolgova, Natalia V., Nehzati, Susan, MacDonald, Tracy C., Summers, Kelly L., Crawford, Andrew M., Krone, Patrick H., George, Graham N., and Pickering, Ingrid J. Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae. United States: N. p., 2019. Web. doi:10.1039/C8MT00315G.
Dolgova, Natalia V., Nehzati, Susan, MacDonald, Tracy C., Summers, Kelly L., Crawford, Andrew M., Krone, Patrick H., George, Graham N., & Pickering, Ingrid J. Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae. United States. doi:10.1039/C8MT00315G.
Dolgova, Natalia V., Nehzati, Susan, MacDonald, Tracy C., Summers, Kelly L., Crawford, Andrew M., Krone, Patrick H., George, Graham N., and Pickering, Ingrid J. Tue . "Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae". United States. doi:10.1039/C8MT00315G.
@article{osti_1504961,
title = {Disruption of selenium transport and function is a major contributor to mercury toxicity in zebrafish larvae},
author = {Dolgova, Natalia V. and Nehzati, Susan and MacDonald, Tracy C. and Summers, Kelly L. and Crawford, Andrew M. and Krone, Patrick H. and George, Graham N. and Pickering, Ingrid J.},
abstractNote = {Mercury blocks selenium transport into and out of cells, disrupting selenoprotein function and preventing synthesis of new selenoproteins and compounds.},
doi = {10.1039/C8MT00315G},
journal = {Metallomics},
issn = {1756-5901},
number = 3,
volume = 11,
place = {United States},
year = {2019},
month = {1}
}