skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Function Coupling Mechanism of PhuS and HemO in Heme Degradation

Journal Article · · Scientific Reports
; ; ; ; ; ORCiD logo; ; ; ; ORCiD logo

Research Organization:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
FOREIGN
OSTI ID:
1503693
Journal Information:
Scientific Reports, Vol. 7, Issue 1; ISSN 2045-2322
Publisher:
Nature Publishing Group
Country of Publication:
United States
Language:
ENGLISH

References (31)

Structural Analysis and Identification of PhuS as a Heme-Degrading Enzyme from Pseudomonas aeruginosa journal May 2014
Quantum Mechanical/Molecular Mechanical Study of Mechanisms of Heme Degradation by the Enzyme Heme Oxygenase:  The Strategic Function of the Water Cluster journal February 2008
Hydroperoxy-Heme Oxygenase Generated by Cryoreduction Catalyzes the Formation of α- meso -Hydroxyheme as Detected by EPR and ENDOR journal November 1999
Crystal Structures of the Ferric, Ferrous, and Ferrous–NO Forms of the Asp140Ala Mutant of Human Heme Oxygenase-1: Catalytic Implications journal July 2003
Development of the Colle-Salvetti correlation-energy formula into a functional of the electron density journal January 1988
The P. aeruginosa Heme Binding Protein PhuS Is a Heme Oxygenase Titratable Regulator of Heme Uptake journal June 2013
The Crystal Structures of the Ferric and Ferrous Forms of the Heme Complex of HmuO, a Heme Oxygenase of Corynebacterium diphtheriae journal November 2003
Solution 1 H NMR Investigation of the Active Site Molecular and Electronic Structures of Substrate-bound, Cyanide-inhibited HmuO, a Bacterial Heme Oxygenase from Corynebacterium diphtheriae journal December 2002
Heme-Containing Oxygenases journal January 1996
The Role of the Cytoplasmic Heme-binding Protein (PhuS) of Pseudomonas aeruginosa in Intracellular Heme Trafficking and Iron Homeostasis journal November 2008
O 2 - and H 2 O 2 -dependent Verdoheme Degradation by Heme Oxygenase journal August 2005
Crystallization and Preliminary X-Ray Diffraction Analysis of a Recombinant Bacterial Heme Oxygenase (Hmu O) from Corynebacterium diphtheriae journal June 1999
Crystal Structure of Heme Oxygenase from the Gram-Negative Pathogen Neisseria meningitidis and a Comparison with Mammalian Heme Oxygenase-1 † journal September 2001
Structural Basis for Novel δ-Regioselective Heme Oxygenation in the Opportunistic Pathogen Pseudomonas aeruginosa † , ‡ journal May 2004
Roles of Distal Asp in Heme Oxygenase from Corynebacterium diphtheriae, HmuO : A WATER-DRIVEN OXYGEN ACTIVATION MECHANISM journal November 2004
Metabolic Flux of Extracellular Heme Uptake in Pseudomonas aeruginosa Is Driven by the Iron-regulated Heme Oxygenase (HemO) journal April 2012
Autocatalytic Radical Reactions in Physiological Prosthetic Heme Modification journal June 2003
Solution 1 H NMR of the Active Site of Substrate-bound, Cyanide-inhibited Human Heme Oxygenase : COMPARISON TO THE CRYSTAL STRUCTURE OF THE WATER-LIGATED FORM journal January 2001
Solution NMR Characterization of an Unusual Distal H-bond Network in the Active Site of the Cyanide-inhibited, Human Heme Oxygenase Complex of the Symmetric Substrate, 2,4-Dimethyldeuterohemin journal June 2002
Crystal Structure of Rat Heme Oxygenase-1 in Complex with Heme Bound to Azide: IMPLICATION FOR REGIOSPECIFIC HYDROXYLATION OF HEME AT THE α- journal September 2002
Ab initio effective core potentials for molecular calculations. Potentials for main group elements Na to Bi journal January 1985
Heme Oxygenase Mechanism:  Evidence for an Electrophilic, Ferric Peroxide Species journal September 1998
The ONIOM Method and Its Applications journal April 2015
A Second Generation Force Field for the Simulation of Proteins, Nucleic Acids, and Organic Molecules journal May 1995
The mechanism of heme oxygenase journal April 2000
Structure and catalytic mechanism of heme oxygenase journal January 2007
Solution 1 H, 15 N NMR Spectroscopic Characterization of Substrate-Bound, Cyanide-Inhibited Human Heme Oxygenase:  Water Occupation of the Distal Cavity journal November 2003
The Hydrogen-Bonding Network in Heme Oxygenase Also Functions as a Modulator of Enzyme Dynamics:  Chaotic Motions upon Disrupting the H-Bond Network in Heme Oxygenase from Pseudomonas aeruginosa journal September 2007
Ferryl Protonation in Oxoiron(IV) Porphyrins and Its Role in Oxygen Transfer journal February 2015
Comparison of the Heme-free and -bound Crystal Structures of Human Heme Oxygenase-1 journal December 2002
1 H NMR Detection of Immobilized Water Molecules within a Strong Distal Hydrogen-Bonding Network of Substrate-Bound Human Heme Oxygenase-1 journal December 2002

Similar Records

Structural Analysis and Identification of PhuS as a Heme-Degrading Enzyme from Pseudomonas aeruginosa
Journal Article · Mon Apr 21 00:00:00 EDT 2014 · J. Mol. Biol. · OSTI ID:1503693
+2 more
New Insight into the Mechanism of Anaerobic Heme Degradation
Journal Article · Tue Oct 01 00:00:00 EDT 2019 · Biochemistry-US · OSTI ID:1503693
+1 more
Electronic Properties of the Highly Ruffled Heme Bound to the Heme Degrading Enzyme Isdi
Journal Article · Mon Sep 09 00:00:00 EDT 2013 · Proc. Natl. Acad. Sci. USA 108:13071,2011 · OSTI ID:1503693
+1 more

Related Subjects