Microfluidic devices for liquid chromatography-mass spectrometry and microscopic imaging
Abstract
Systems, methods, and apparatus provide integration of microscopic imaging and liquid chromatography-mass spectrometry on a microfluidic device. In one aspect, an apparatus includes a first wafer, a second wafer, and an emitter. The emitter is disposed between the first wafer and the second wafer. The first wafer defines a sample input hole. The first wafer and the second wafer define a first channel, the first channel including a first end and a second end. The first end of the first channel is proximate the sample input hole. The first channel is configured to contain separation media. The second end of the first channel is proximate the emitter.
- Inventors:
- Publication Date:
- Research Org.:
- Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1502820
- Patent Number(s):
- 10,203,307
- Application Number:
- 14/729,999
- Assignee:
- The Regents of the University of California (Oakland, CA)
- DOE Contract Number:
- AC02-05CH11231
- Resource Type:
- Patent
- Resource Relation:
- Patent File Date: 2015 Jun 03
- Country of Publication:
- United States
- Language:
- English
- Subject:
- 37 INORGANIC, ORGANIC, PHYSICAL, AND ANALYTICAL CHEMISTRY
Citation Formats
Wang, Daojing, Mao, Pan, Gomez-Sjoberg, Rafael, Wang, Hung-Tu, and Yang, Peidong. Microfluidic devices for liquid chromatography-mass spectrometry and microscopic imaging. United States: N. p., 2019.
Web.
Wang, Daojing, Mao, Pan, Gomez-Sjoberg, Rafael, Wang, Hung-Tu, & Yang, Peidong. Microfluidic devices for liquid chromatography-mass spectrometry and microscopic imaging. United States.
Wang, Daojing, Mao, Pan, Gomez-Sjoberg, Rafael, Wang, Hung-Tu, and Yang, Peidong. Tue .
"Microfluidic devices for liquid chromatography-mass spectrometry and microscopic imaging". United States. https://www.osti.gov/servlets/purl/1502820.
@article{osti_1502820,
title = {Microfluidic devices for liquid chromatography-mass spectrometry and microscopic imaging},
author = {Wang, Daojing and Mao, Pan and Gomez-Sjoberg, Rafael and Wang, Hung-Tu and Yang, Peidong},
abstractNote = {Systems, methods, and apparatus provide integration of microscopic imaging and liquid chromatography-mass spectrometry on a microfluidic device. In one aspect, an apparatus includes a first wafer, a second wafer, and an emitter. The emitter is disposed between the first wafer and the second wafer. The first wafer defines a sample input hole. The first wafer and the second wafer define a first channel, the first channel including a first end and a second end. The first end of the first channel is proximate the sample input hole. The first channel is configured to contain separation media. The second end of the first channel is proximate the emitter.},
doi = {},
url = {https://www.osti.gov/biblio/1502820},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2019},
month = {2}
}
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