Skip to main content
U.S. Department of Energy
Office of Scientific and Technical Information

Miniaturized pulsed discharge ionization detector, non-radioactive ionization sources, and methods thereof

Patent ·
OSTI ID:1502435

The present application relates to pulsed discharge ionization detectors (PDIDs) and non-radioactive ionization sources, including miniaturized forms thereof. In some examples, the PDID includes annular electrodes, where each electrode is disposed between annular insulators. Also provided herein are methods of making and using such PDIDs, such as for detecting one or more volatile organic compounds, as well as non-radioactive ionization sources.

Research Organization:
Sandia National Laboratories (SNL-NM), Albuquerque, NM (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
AC04-94AL85000
Assignee:
National Technology & Engineering Solutions of Sandia, LLC (Albuquerque, NM)
Patent Number(s):
10,197,532
Application Number:
14/992,855
OSTI ID:
1502435
Country of Publication:
United States
Language:
English

References (49)

High-speed two-dimensional gas chromatography using microfabricated GC columns combined with nanoelectromechanical mass sensors conference June 2009
Studies of trans-3-methyl-2-hexenoic acid in normal and schizophrenic humans journal July 1973
Active MEMS Valves for Flow Control in a High-Pressure Micro-Gas-Analyzer journal October 2011
Isothermal mass flow measurements in microfabricated rectangular channels over a very wide Knudsen range journal April 2014
Invited Article: A materials investigation of a phase-change micro-valve for greenhouse gas collection and other potential applications journal March 2012
Gas chromatographic analysis of trace gas impurities in tungsten hexafluoride journal March 2001
Mass-Sensitive Microfabricated Chemical Preconcentrator journal December 2008
Stability of methylnicotinate in aqueous solution as utilized in the 'niacin patch test' journal January 2008
A micro-discharge photoionization detector for micro-gas chromatography journal December 2013
Windowless pulsed-discharge photoionization detector application to qualitative analysis of volatile organic compounds journal February 1996
The predictive power of SIMION/SDS simulation software for modeling ion mobility spectrometry instruments journal September 2008
Fast Detection of Volatile Organic Compounds from Bacterial Cultures by Secondary Electrospray Ionization-Mass Spectrometry journal October 2010
Evaluation of the pulsed discharge helium ionization detector for the analysis of hydrogen and methane in breath journal February 2004
Rapid detection of pathogenic bacteria by volatile organic compound (VOC) analysis conference February 2002
Performance Characteristics of the Aerosol Collectors of the Autonomous Pathogen Detection System (APDS) journal May 2005
Zoonotic aspects of Mycobacterium bovis and Mycobacterium avium-intracellulare complex (MAC) journal May 2005
On-Line Monitoring of Microbial Volatile Metabolites by Proton Transfer Reaction-Mass Spectrometry journal February 2008
Pulsed discharge helium ionization detector with multiple combined bias/collecting electrodes for gas chromatography journal April 2013
The scent of Mycobacterium tuberculosis – Part II breath journal July 2009
Micro gas analyzers for environmental and medical applications journal July 2008
simion for the personal computer in reflection journal December 2000
Recent advancements in the gas-phase MicroChemLab journal June 2006
Individual Comparisons of the Levels of (E)-3-Methyl-2-Hexenoic Acid, an Axillary Odor-Related Compound, in Japanese journal April 2006
Ion mobility spectrometry for microbial volatile organic compounds: a new identification tool for human pathogenic bacteria journal February 2012
Detection of organotin, organomercury, and organolead compounds with a pulsed discharge detector (PDD) journal August 2002
Microfabricated planar glass gas chromatography with photoionization detection journal January 2010
Design Considerations for High Throughput Screening and In Vitro Diagnostic Assays journal July 2007
A Monolithically-Integrated μGC Chemical Sensor System journal June 2011
Production of volatile organic compounds by mycobacteria journal January 2012
Application of Gas Chromatography with a Pulsed Discharge Helium Ionization Detector for Measurements of Molecular Hydrogen in the Atmosphere journal April 2009
Recovery of Mycobacterium bovis from Soft Fresh Cheese Originating in Mexico journal December 2006
Characterization of a micro-helium discharge detector for gas chromatography journal January 2015
Rapid detection methods for viable Mycobacterium avium subspecies paratuberculosis in milk and cheese journal July 2010
Diagnostic potential of the pulsed discharged helium ionization detector (PDHID) for pathogenic Mycobacterial volatile biomarkers journal July 2013
Pulsed discharge emission detector: an element-selective detector for gas chromatography journal March 2000
Detection of volatile metabolites produced by bacterial growth in blood culture media by selected ion flow tube mass spectrometry (SIFT-MS) journal May 2006
Volatile compound profiling for the identification of Gram-negative bacteria by ion-molecule reaction-mass spectrometry journal August 2012
Development of a Mesoscale Pulsed Discharge Helium Ionization Detector for Portable Gas Chromatography journal January 2015
Hybrid integration of injector and detector functions for microchip gas chromatography journal January 2010
Universal and discriminative detection using a miniaturized pulsed discharge detector in comprehensive two-dimensional GC journal November 2006
Radioimmunoassay of tuberculoprotein derived from Mycobacterium tuberculosis. journal July 1980
The scent of Mycobacterium tuberculosis journal July 2008
Molecular analysis of volatile metabolites released specifically by staphylococcus aureus and pseudomonas aeruginosa journal January 2012
Testing capillary gas chromatographic columns journal November 1981
Characterization of the Pulsed Discharge Electron Capture Detector journal January 1996
Evaluation of a combination of SIFT-MS and multivariate data analysis for the diagnosis of Mycobacterium bovis in wild badgers journal January 2009
Comparison of ion trajectories in vacuum and viscous environments using SIMION: Insights for instrument design journal October 2007
Comprehensive, standardized quality test for glass capillary columns journal August 1978
Pulsed discharge detector: theory and applications journal September 2004