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Title: A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ

Authors:
ORCiD logo [1];  [2]; ORCiD logo [3];  [4];  [5];  [6];  [5];  [7]; ORCiD logo [8]
  1. Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue Ann Arbor MI 48109-2216 USA; Department of Medicinal Chemistry, University of Michigan, Ann Arbor MI 48109 USA
  2. Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue Ann Arbor MI 48109-2216 USA; Baruch S. Blumberg Institute, Natural Products Discovery Institute, 3805 Old Easton Road Doylestown PA 18902 USA
  3. Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue Ann Arbor MI 48109-2216 USA; Department of Biological Chemistry, University of Michigan, 1150 W. Medical Center Drive Ann Arbor MI 48109 USA; Epigenetics and Stem Cell Biology Laboratory, National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park NC 27709 USA
  4. Department of Pathology, University of Michigan, Ann Arbor MI 48109 USA
  5. Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor MI 48109 USA
  6. Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue Ann Arbor MI 48109-2216 USA
  7. Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue Ann Arbor MI 48109-2216 USA; Department of Biological Chemistry, University of Michigan, 1150 W. Medical Center Drive Ann Arbor MI 48109 USA
  8. Life Sciences Institute, University of Michigan, 210 Washtenaw Avenue Ann Arbor MI 48109-2216 USA; Department of Medicinal Chemistry, University of Michigan, Ann Arbor MI 48109 USA; Department of Chemistry, University of Michigan, Ann Arbor MI 48109 USA; Department of Microbiology and Immunology, University of Michigan, Ann Arbor MI 48109 USA
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
NIHNIGMS
OSTI Identifier:
1502225
Resource Type:
Journal Article
Journal Name:
ChemBioChem: a European journal of chemical biology
Additional Journal Information:
Journal Volume: 19; Journal Issue: 15; Journal ID: ISSN 1439-4227
Publisher:
ChemPubSoc Europe
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Tripathi, Ashootosh, Park, Sung Ryeol, Sikkema, Andrew P., Cho, Hyo Je, Wu, Jianfeng, Lee, Brian, Xi, Chuanwu, Smith, Janet L., and Sherman, David H. A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ. United States: N. p., 2018. Web. doi:10.1002/cbic.201800233.
Tripathi, Ashootosh, Park, Sung Ryeol, Sikkema, Andrew P., Cho, Hyo Je, Wu, Jianfeng, Lee, Brian, Xi, Chuanwu, Smith, Janet L., & Sherman, David H. A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ. United States. doi:10.1002/cbic.201800233.
Tripathi, Ashootosh, Park, Sung Ryeol, Sikkema, Andrew P., Cho, Hyo Je, Wu, Jianfeng, Lee, Brian, Xi, Chuanwu, Smith, Janet L., and Sherman, David H. Thu . "A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ". United States. doi:10.1002/cbic.201800233.
@article{osti_1502225,
title = {A Defined and Flexible Pocket Explains Aryl Substrate Promiscuity of the Cahuitamycin Starter Unit-Activating Enzyme CahJ},
author = {Tripathi, Ashootosh and Park, Sung Ryeol and Sikkema, Andrew P. and Cho, Hyo Je and Wu, Jianfeng and Lee, Brian and Xi, Chuanwu and Smith, Janet L. and Sherman, David H.},
abstractNote = {},
doi = {10.1002/cbic.201800233},
journal = {ChemBioChem: a European journal of chemical biology},
issn = {1439-4227},
number = 15,
volume = 19,
place = {United States},
year = {2018},
month = {6}
}

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