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Title: Discovery of Potent 2-Aryl-6,7-dihydro-5 H -pyrrolo[1,2- a ]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design

Authors:
; ; ; ORCiD logo; ; ; ; ; ; ; ; ; ; ; ; ; ; ORCiD logo
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
NCINIH
OSTI Identifier:
1499757
Resource Type:
Journal Article
Journal Name:
Journal of Medicinal Chemistry
Additional Journal Information:
Journal Volume: 61; Journal Issue: 13; Journal ID: ISSN 0022-2623
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Wang, Feng, Jeon, Kyu Ok, Salovich, James M., Macdonald, Jonathan D., Alvarado, Joseph, Gogliotti, Rocco D., Phan, Jason, Olejniczak, Edward T., Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P., Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W., Tansey, William P., Stauffer, Shaun R., and Fesik, Stephen W. Discovery of Potent 2-Aryl-6,7-dihydro-5 H -pyrrolo[1,2- a ]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design. United States: N. p., 2018. Web. doi:10.1021/acs.jmedchem.8b00375.
Wang, Feng, Jeon, Kyu Ok, Salovich, James M., Macdonald, Jonathan D., Alvarado, Joseph, Gogliotti, Rocco D., Phan, Jason, Olejniczak, Edward T., Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P., Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W., Tansey, William P., Stauffer, Shaun R., & Fesik, Stephen W. Discovery of Potent 2-Aryl-6,7-dihydro-5 H -pyrrolo[1,2- a ]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design. United States. doi:10.1021/acs.jmedchem.8b00375.
Wang, Feng, Jeon, Kyu Ok, Salovich, James M., Macdonald, Jonathan D., Alvarado, Joseph, Gogliotti, Rocco D., Phan, Jason, Olejniczak, Edward T., Sun, Qi, Wang, Shidong, Camper, DeMarco, Yuh, Joannes P., Shaw, J. Grace, Sai, Jiqing, Rossanese, Olivia W., Tansey, William P., Stauffer, Shaun R., and Fesik, Stephen W. Tue . "Discovery of Potent 2-Aryl-6,7-dihydro-5 H -pyrrolo[1,2- a ]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design". United States. doi:10.1021/acs.jmedchem.8b00375.
@article{osti_1499757,
title = {Discovery of Potent 2-Aryl-6,7-dihydro-5 H -pyrrolo[1,2- a ]imidazoles as WDR5-WIN-Site Inhibitors Using Fragment-Based Methods and Structure-Based Design},
author = {Wang, Feng and Jeon, Kyu Ok and Salovich, James M. and Macdonald, Jonathan D. and Alvarado, Joseph and Gogliotti, Rocco D. and Phan, Jason and Olejniczak, Edward T. and Sun, Qi and Wang, Shidong and Camper, DeMarco and Yuh, Joannes P. and Shaw, J. Grace and Sai, Jiqing and Rossanese, Olivia W. and Tansey, William P. and Stauffer, Shaun R. and Fesik, Stephen W.},
abstractNote = {},
doi = {10.1021/acs.jmedchem.8b00375},
journal = {Journal of Medicinal Chemistry},
issn = {0022-2623},
number = 13,
volume = 61,
place = {United States},
year = {2018},
month = {1}
}