skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Ferric pyrophosphate citrate: interactions with transferrin

ORCiD logo; ; ;
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
USDOE Office of Science (SC)
OSTI Identifier:
Resource Type:
Journal Article
Journal Name:
Additional Journal Information:
Journal Volume: 31; Journal Issue: 6; Journal ID: ISSN 0966-0844
Springer Netherlands
Country of Publication:
United States

Citation Formats

Pratt, Raymond, Handelman, Garry J., Edwards, Thomas E., and Gupta, Ajay. Ferric pyrophosphate citrate: interactions with transferrin. United States: N. p., 2018. Web. doi:10.1007/s10534-018-0142-2.
Pratt, Raymond, Handelman, Garry J., Edwards, Thomas E., & Gupta, Ajay. Ferric pyrophosphate citrate: interactions with transferrin. United States. doi:10.1007/s10534-018-0142-2.
Pratt, Raymond, Handelman, Garry J., Edwards, Thomas E., and Gupta, Ajay. Thu . "Ferric pyrophosphate citrate: interactions with transferrin". United States. doi:10.1007/s10534-018-0142-2.
title = {Ferric pyrophosphate citrate: interactions with transferrin},
author = {Pratt, Raymond and Handelman, Garry J. and Edwards, Thomas E. and Gupta, Ajay},
abstractNote = {},
doi = {10.1007/s10534-018-0142-2},
journal = {Biometals},
issn = {0966-0844},
number = 6,
volume = 31,
place = {United States},
year = {2018},
month = {10}

Works referenced in this record:

A randomized controlled study of iron supplementation in patients treated with erythropoietin
journal, November 1996

  • Macdougall, Iain C.; Tucker, Beatriz; Thompson, Joanne
  • Kidney International, Vol. 50, Issue 5
  • DOI: 10.1038/ki.1996.487

Iron and bismuth bound human serum transferrin reveals a partially-opened conformation in the N-lobe
journal, December 2012

  • Yang, Nan; Zhang, Hongmin; Wang, Minji
  • Scientific Reports, Vol. 2, Issue 1
  • DOI: 10.1038/srep00999

Nonequivalence of the metal binding sites in vanadyl-labeled human serum transferrin
journal, October 1975

  • Cannon, James C.; Chasteen, N. Dennis
  • Biochemistry, Vol. 14, Issue 21
  • DOI: 10.1021/bi00692a003

The Crystal Structure of Iron-free Human Serum Transferrin Provides Insight into Inter-lobe Communication and Receptor Binding
journal, June 2006

  • Wally, Jeremy; Halbrooks, Peter J.; Vonrhein, Clemens
  • Journal of Biological Chemistry, Vol. 281, Issue 34
  • DOI: 10.1074/jbc.M604592200

Iron exchange between transferrin molecules mediated by phosphate compounds and other cell metabolites
journal, August 1977

Labile plasma iron in iron overload: redox activity and susceptibility to chelation
journal, October 2003

Pathways for the regulation of body iron homeostasis in response to experimental iron overload
journal, October 2005

MolProbity : all-atom structure validation for macromolecular crystallography
journal, December 2009

  • Chen, Vincent B.; Arendall, W. Bryan; Headd, Jeffrey J.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 1
  • DOI: 10.1107/S0907444909042073

Coot model-building tools for molecular graphics
journal, November 2004

  • Emsley, Paul; Cowtan, Kevin
  • Acta Crystallographica Section D Biological Crystallography, Vol. 60, Issue 12, p. 2126-2132
  • DOI: 10.1107/S0907444904019158

Correction of Uremic Iron Deficiency Anemia in Hemodialyzed Patients: A Prospective Study
journal, January 1998

  • Fudin, Roberto; Jaichenko, Jose; Shostak, Avshalom
  • Nephron, Vol. 79, Issue 3
  • DOI: 10.1159/000045053

Ferrous iron content of intravenous iron formulations
journal, March 2016

Difference between the two iron-binding sites of transferrin
journal, May 1975

  • Princiotto, J. V.; Zapolski, E. J.
  • Nature, Vol. 255, Issue 5503
  • DOI: 10.1038/255087a0

Iron levels in polarized macrophages: Regulation of immunity and autoimmunity
journal, October 2012

REFMAC 5 for the refinement of macromolecular crystal structures
journal, March 2011

  • Murshudov, Garib N.; Skubák, Pavol; Lebedev, Andrey A.
  • Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4
  • DOI: 10.1107/S0907444911001314

Forms of iron transferrin
journal, January 1980

Iron Sucrose Impairs Phagocytic Function and Promotes Apoptosis in Polymorphonuclear Leukocytes
journal, January 2012

  • Ichii, Hirohito; Masuda, Yuichi; Hassanzadeh, Tania
  • American Journal of Nephrology, Vol. 36, Issue 1
  • DOI: 10.1159/000339285

Iatrogenic Iron Overload in Dialysis Patients at the Beginning of the 21st Century
journal, April 2016

PHENIX : building new software for automated crystallographic structure determination
journal, October 2002

  • Adams, Paul D.; Grosse-Kunstleve, Ralf W.; Hung, Li-Wei
  • Acta Crystallographica Section D Biological Crystallography, Vol. 58, Issue 11
  • DOI: 10.1107/S0907444902016657

Treatment of iron deficiency anemia: Are monomeric iron compounds suitable for parenteral administration?
journal, November 2000

  • Gupta, Ajay; Crumbliss, Alvin L.
  • Journal of Laboratory and Clinical Medicine, Vol. 136, Issue 5
  • DOI: 10.1067/mlc.2000.110368

The MORPHEUS protein crystallization screen
journal, November 2009

Structural basis for iron piracy by pathogenic Neisseria
journal, February 2012

  • Noinaj, Nicholas; Easley, Nicole C.; Oke, Muse
  • Nature, Vol. 483, Issue 7387
  • DOI: 10.1038/nature10823

Transferrin as a donor of iron to mitochondria Effect of pyrophosphate and relationship to mitochondrial metabolism and heme synthesis
journal, December 1984

Iron transfer from transferrin mediated by polyphosphate compounds
journal, November 1981

  • Konopka, Krystyna; Mareschal, Jean-Claude; Crichton, Robert R.
  • Biochimica et Biophysica Acta (BBA) - General Subjects, Vol. 677, Issue 3-4
  • DOI: 10.1016/0304-4165(81)90255-5

Ferric pyrophosphate citrate (Triferic™) administration via the dialysate maintains hemoglobin and iron balance in chronic hemodialysis patients
journal, July 2015

  • Fishbane, Steven N.; Singh, Ajay K.; Cournoyer, Serge H.
  • Nephrology Dialysis Transplantation, Vol. 30, Issue 12
  • DOI: 10.1093/ndt/gfv277

The Pharmacokinetics and Pharmacodynamics of Iron Preparations
journal, January 2011

Modern iron replacement therapy: clinical and pathophysiological insights
journal, December 2017

  • Girelli, Domenico; Ugolini, Sara; Busti, Fabiana
  • International Journal of Hematology, Vol. 107, Issue 1
  • DOI: 10.1007/s12185-017-2373-3

journal, January 2010

  • Kabsch, Wolfgang
  • Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 2
  • DOI: 10.1107/S0907444909047337

An unrestrained proinflammatory M1 macrophage population induced by iron impairs wound healing in humans and mice
journal, March 2011

  • Sindrilaru, Anca; Peters, Thorsten; Wieschalka, Stefan
  • Journal of Clinical Investigation, Vol. 121, Issue 3
  • DOI: 10.1172/JCI44490

Iron Sucrose Promotes Endothelial Injury and Dysfunction and Monocyte Adhesion/Infiltration
journal, January 2012

  • Kamanna, Vaijinath S.; Ganji, Shobha H.; Shelkovnikov, Stanislav
  • American Journal of Nephrology, Vol. 35, Issue 2
  • DOI: 10.1159/000334939

Phaser crystallographic software
journal, July 2007

  • McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D.
  • Journal of Applied Crystallography, Vol. 40, Issue 4
  • DOI: 10.1107/S0021889807021206

Pharmacokinetics of Ferric Pyrophosphate Citrate, a Novel Iron Salt, Administered Intravenously to Healthy Volunteers: Journal of Clinical Pharmacology
journal, October 2016

  • Pratt, Raymond D.; Swinkels, Dorine W.; Ikizler, T. Alp
  • The Journal of Clinical Pharmacology, Vol. 57, Issue 3
  • DOI: 10.1002/jcph.819