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Title: Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS

Authors:
ORCiD logo; ORCiD logo; ; ORCiD logo; ; ORCiD logo; ORCiD logo; ; ; ; ; ; ; ; ;  [1];  [1]; ; ;  [2] more »;  [1]; ORCiD logo [2] « less
  1. Boehringer Ingelheim RCV GmbH &, Co. KG, Doktor-Boehringer-Gasse 5-11, 1120 Vienna, Austria
  2. Department of Chemistry, Vanderbilt University, Nashville, Tennessee 37232-0146, United States
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
National Institutes of Health (NIH)
OSTI Identifier:
1499729
Resource Type:
Journal Article
Journal Name:
Journal of Medicinal Chemistry
Additional Journal Information:
Journal Volume: 61; Journal Issue: 19; Journal ID: ISSN 0022-2623
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Hodges, Timothy R., Abbott, Jason R., Little, Andrew J., Sarkar, Dhruba, Salovich, James M., Howes, Jennifer E., Akan, Denis T., Sai, Jiqing, Arnold, Allison L., Browning, Carrie, Burns, Michael C., Sobolik, Tammy, Sun, Qi, Beesetty, Yugandhar, Coker, Jesse A., Scharn, Dirk, Stadtmueller, Heinz, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., McConnell, Darryl B., and Fesik, Stephen W. Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS. United States: N. p., 2018. Web. doi:10.1021/acs.jmedchem.8b01108.
Hodges, Timothy R., Abbott, Jason R., Little, Andrew J., Sarkar, Dhruba, Salovich, James M., Howes, Jennifer E., Akan, Denis T., Sai, Jiqing, Arnold, Allison L., Browning, Carrie, Burns, Michael C., Sobolik, Tammy, Sun, Qi, Beesetty, Yugandhar, Coker, Jesse A., Scharn, Dirk, Stadtmueller, Heinz, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., McConnell, Darryl B., & Fesik, Stephen W. Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS. United States. doi:10.1021/acs.jmedchem.8b01108.
Hodges, Timothy R., Abbott, Jason R., Little, Andrew J., Sarkar, Dhruba, Salovich, James M., Howes, Jennifer E., Akan, Denis T., Sai, Jiqing, Arnold, Allison L., Browning, Carrie, Burns, Michael C., Sobolik, Tammy, Sun, Qi, Beesetty, Yugandhar, Coker, Jesse A., Scharn, Dirk, Stadtmueller, Heinz, Rossanese, Olivia W., Phan, Jason, Waterson, Alex G., McConnell, Darryl B., and Fesik, Stephen W. Wed . "Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS". United States. doi:10.1021/acs.jmedchem.8b01108.
@article{osti_1499729,
title = {Discovery and Structure-Based Optimization of Benzimidazole-Derived Activators of SOS1-Mediated Nucleotide Exchange on RAS},
author = {Hodges, Timothy R. and Abbott, Jason R. and Little, Andrew J. and Sarkar, Dhruba and Salovich, James M. and Howes, Jennifer E. and Akan, Denis T. and Sai, Jiqing and Arnold, Allison L. and Browning, Carrie and Burns, Michael C. and Sobolik, Tammy and Sun, Qi and Beesetty, Yugandhar and Coker, Jesse A. and Scharn, Dirk and Stadtmueller, Heinz and Rossanese, Olivia W. and Phan, Jason and Waterson, Alex G. and McConnell, Darryl B. and Fesik, Stephen W.},
abstractNote = {},
doi = {10.1021/acs.jmedchem.8b01108},
journal = {Journal of Medicinal Chemistry},
issn = {0022-2623},
number = 19,
volume = 61,
place = {United States},
year = {2018},
month = {5}
}