skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design

Authors:
ORCiD logo [1];  [2];  [2];  [2];  [3];  [1];  [1];  [2];  [2];  [2];  [2];  [1];  [2];  [2];  [2];  [2];  [2];  [3];  [2];  [3] more »;  [1];  [1];  [3];  [3];  [2];  [2];  [2];  [2];  [1];  [2];  [1];  [2]; ORCiD logo [2];  [1];  [1];  [1];  [1] « less
  1. AbbVie Bioresearch Center, 381 Plantation Street, Worcester, Massachusetts 01605, United States
  2. AbbVie, Inc., 1 North Waukegan Road, North Chicago, Illinois 60064, United States
  3. AbbVie Deutschland GmbH &, Co. KG, Knollstrasse 50, 67061, Ludwigshafen, Germany
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
INDUSTRY
OSTI Identifier:
1499728
Resource Type:
Journal Article
Journal Name:
Journal of Medicinal Chemistry
Additional Journal Information:
Journal Volume: 61; Journal Issue: 24; Journal ID: ISSN 0022-2623
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Hobson, Adrian D., Judge, Russell A., Aguirre, Ana L., Brown, Brian S., Cui, Yifang, Ding, Ping, Dominguez, Eric, DiGiammarino, Enrico, Egan, David A., Freiberg, Gail M., Gopalakrishnan, Sujatha M., Harris, Christopher M., Honore, Marie P., Kage, Karen L., Kapecki, Nicolas J., Ling, Christopher, Ma, Junli, Mack, Helmut, Mamo, Mulugeta, Maurus, Stefan, McRae, Bradford, Moore, Nigel S., Mueller, Bernhard K., Mueller, Reinhold, Namovic, Marian T., Patel, Kaushal, Pratt, Steve D., Putman, C. Brent, Queeney, Kara L., Sarris, Kathy K., Schaffter, Lisa M., Stoll, Vincent, Vasudevan, Anil, Wang, Lei, Wang, Lu, Wirthl, William, and Yach, Kimberly. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design. United States: N. p., 2018. Web. doi:10.1021/acs.jmedchem.8b01098.
Hobson, Adrian D., Judge, Russell A., Aguirre, Ana L., Brown, Brian S., Cui, Yifang, Ding, Ping, Dominguez, Eric, DiGiammarino, Enrico, Egan, David A., Freiberg, Gail M., Gopalakrishnan, Sujatha M., Harris, Christopher M., Honore, Marie P., Kage, Karen L., Kapecki, Nicolas J., Ling, Christopher, Ma, Junli, Mack, Helmut, Mamo, Mulugeta, Maurus, Stefan, McRae, Bradford, Moore, Nigel S., Mueller, Bernhard K., Mueller, Reinhold, Namovic, Marian T., Patel, Kaushal, Pratt, Steve D., Putman, C. Brent, Queeney, Kara L., Sarris, Kathy K., Schaffter, Lisa M., Stoll, Vincent, Vasudevan, Anil, Wang, Lei, Wang, Lu, Wirthl, William, & Yach, Kimberly. Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design. United States. doi:10.1021/acs.jmedchem.8b01098.
Hobson, Adrian D., Judge, Russell A., Aguirre, Ana L., Brown, Brian S., Cui, Yifang, Ding, Ping, Dominguez, Eric, DiGiammarino, Enrico, Egan, David A., Freiberg, Gail M., Gopalakrishnan, Sujatha M., Harris, Christopher M., Honore, Marie P., Kage, Karen L., Kapecki, Nicolas J., Ling, Christopher, Ma, Junli, Mack, Helmut, Mamo, Mulugeta, Maurus, Stefan, McRae, Bradford, Moore, Nigel S., Mueller, Bernhard K., Mueller, Reinhold, Namovic, Marian T., Patel, Kaushal, Pratt, Steve D., Putman, C. Brent, Queeney, Kara L., Sarris, Kathy K., Schaffter, Lisa M., Stoll, Vincent, Vasudevan, Anil, Wang, Lei, Wang, Lu, Wirthl, William, and Yach, Kimberly. Thu . "Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design". United States. doi:10.1021/acs.jmedchem.8b01098.
@article{osti_1499728,
title = {Identification of Selective Dual ROCK1 and ROCK2 Inhibitors Using Structure-Based Drug Design},
author = {Hobson, Adrian D. and Judge, Russell A. and Aguirre, Ana L. and Brown, Brian S. and Cui, Yifang and Ding, Ping and Dominguez, Eric and DiGiammarino, Enrico and Egan, David A. and Freiberg, Gail M. and Gopalakrishnan, Sujatha M. and Harris, Christopher M. and Honore, Marie P. and Kage, Karen L. and Kapecki, Nicolas J. and Ling, Christopher and Ma, Junli and Mack, Helmut and Mamo, Mulugeta and Maurus, Stefan and McRae, Bradford and Moore, Nigel S. and Mueller, Bernhard K. and Mueller, Reinhold and Namovic, Marian T. and Patel, Kaushal and Pratt, Steve D. and Putman, C. Brent and Queeney, Kara L. and Sarris, Kathy K. and Schaffter, Lisa M. and Stoll, Vincent and Vasudevan, Anil and Wang, Lei and Wang, Lu and Wirthl, William and Yach, Kimberly},
abstractNote = {},
doi = {10.1021/acs.jmedchem.8b01098},
journal = {Journal of Medicinal Chemistry},
issn = {0022-2623},
number = 24,
volume = 61,
place = {United States},
year = {2018},
month = {11}
}