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Title: Exchange-coupled Fe3O4/CoFe2O4 nanoparticles for advanced magnetic hyperthermia

Journal Article · · AIP Advances
DOI:https://doi.org/10.1063/1.5007249· OSTI ID:1499262
 [1];  [1];  [2];  [1];  [1]
  1. Univ. of South Florida, Tampa, FL (United States)
  2. Univ. of South Florida, Tampa, FL (United States); Univ. of Scranton, PA (United States)
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We report a systematic study of the effects of core and shell size on the magnetic properties and heating efficiency of exchange-coupled Fe3O4/CoFe2O4 core/shell nanoparticles. The nanoparticles were synthesized using thermal decomposition of organometallic precursors. Transmission electron microscopy (TEM) confirmed the formation of spherical Fe3O4 and Fe3O4/CoFe2O4 nanoparticles. Magnetic measurements showed high saturation magnetization for the nanoparticles at room temperature. Increasing core diameter (6.4±0.7, 7.8±0.1, 9.6±1.2 nm) and/or shell thickness (~1, 2, 4 nm) increased the coercive field (HC), while an optimal value of saturation magnetization (MS) was achieved for the Fe3O4 (7.8±0.1nm)/CoFe2O4 (2.1±0.1nm) nanoparticles. Magnetic hyperthermia measurements indicated a large increase in specific absorption rate (SAR) for 8.2±1.1 nm Fe3O4/CoFe2O4 compared to Fe3O4 nanoparticles of same size. The SAR of the Fe3O4/CoFe2O4 nanoparticles increased from 199 to 461 W/g for 800 Oe as the thickness of the CoFe2O4 shell was increased from 0.9±0.5 to 2.1±0.1 nm. The SAR enhancement is attributed to a combination of the large MS and the large HC. Therefore, these Fe3O4/CoFe2O4 core/shell nanoparticles can be a good candidate for advanced hyperthermia application.

Research Organization:
Univ. of South Florida, Tampa, FL (United States)
Sponsoring Organization:
USDOE Office of Science (SC), Basic Energy Sciences (BES)
Grant/Contract Number:
FG02-07ER46438
OSTI ID:
1499262
Alternate ID(s):
OSTI ID: 1415887
Journal Information:
AIP Advances, Vol. 8, Issue 5; ISSN 2158-3226
Publisher:
American Institute of Physics (AIP)Copyright Statement
Country of Publication:
United States
Language:
English

References (15)

Nano-objects for Addressing the Control of Nanoparticle Arrangement and Performance in Magnetic Hyperthermia journal January 2015
Magnetic particle hyperthermia: nanoparticle magnetism and materials development for cancer therapy journal September 2006
Anisotropy effects in magnetic hyperthermia: A comparison between spherical and cubic exchange-coupled FeO/Fe 3 O 4 nanoparticles journal May 2015
Boosted Hyperthermia Therapy by Combined AC Magnetic and Photothermal Exposures in Ag/Fe 3 O 4 Nanoflowers journal September 2016
Dynamics of magnetic nanoparticle in a viscous liquid: Application to magnetic nanoparticle hyperthermia journal July 2012
Synthesis of Trimagnetic Multishell MnFe 2 O 4 @CoFe 2 O 4 @NiFe 2 O 4 Nanoparticles journal February 2015
Nanoscale Magnetism Control via Surface and Exchange Anisotropy for Optimized Ferrimagnetic Hysteresis journal June 2012
Monodisperse MFe 2 O 4 (M = Fe, Co, Mn) Nanoparticles journal January 2004
Simple models for dynamic hysteresis loop calculations of magnetic single-domain nanoparticles: Application to magnetic hyperthermia optimization journal April 2011
Physics of heat generation using magnetic nanoparticles for hyperthermia journal October 2013
Tunable High Aspect Ratio Iron Oxide Nanorods for Enhanced Hyperthermia journal April 2016
Magnetic nanoparticle heating and heat transfer on a microscale: Basic principles, realities and physical limitations of hyperthermia for tumour therapy journal August 2013
Core/shell iron/iron oxide nanoparticles: are they promising for magnetic hyperthermia? journal January 2016
Ultrathin Interface Regime of Core–Shell Magnetic Nanoparticles for Effective Magnetism Tailoring journal January 2017
Exchange-coupled magnetic nanoparticles for efficient heat induction journal June 2011

Cited By (5)

Readiness of Magnetic Nanobiosensors for Point-of-Care Commercialization journal May 2019
Polymer-coated cobalt ferrite nanoparticles: synthesis, characterization, and toxicity for hyperthermia applications journal January 2018
Fabrication of core–shell CoFe 2 O 4 @HAp nanoparticles: a novel magnetic platform for biomedical applications journal January 2019
Magnetic Vortex and Hyperthermia Suppression in Multigrain Iron Oxide Nanorings journal January 2020
Inductive Thermal Effect of Ferrite Magnetic Nanoparticles journal September 2019

Figures / Tables (5)

FIG. 1.(p. 4)figure FIG. 1.
FIG. 2.(p. 5)figure FIG. 2.
TABLE I(p. 5)table TABLE I
FIG. 3.(p. 6)figure FIG. 3.
FIG. 4.(p. 6)figure FIG. 4.

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