skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo

Authors:
; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; ; more »; ; ; « less
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
National Institutes of Health (NIH)
OSTI Identifier:
1497151
Resource Type:
Journal Article
Journal Name:
Cancer Cell
Additional Journal Information:
Journal Volume: 27; Journal Issue: 4; Journal ID: ISSN 1535-6108
Publisher:
Elsevier
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Borkin, Dmitry, He, Shihan, Miao, Hongzhi, Kempinska, Katarzyna, Pollock, Jonathan, Chase, Jennifer, Purohit, Trupta, Malik, Bhavna, Zhao, Ting, Wang, Jingya, Wen, Bo, Zong, Hongliang, Jones, Morgan, Danet-Desnoyers, Gwenn, Guzman, Monica L., Talpaz, Moshe, Bixby, Dale L., Sun, Duxin, Hess, Jay L., Muntean, Andrew G., Maillard, Ivan, Cierpicki, Tomasz, and Grembecka, Jolanta. Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo. United States: N. p., 2015. Web. doi:10.1016/j.ccell.2015.02.016.
Borkin, Dmitry, He, Shihan, Miao, Hongzhi, Kempinska, Katarzyna, Pollock, Jonathan, Chase, Jennifer, Purohit, Trupta, Malik, Bhavna, Zhao, Ting, Wang, Jingya, Wen, Bo, Zong, Hongliang, Jones, Morgan, Danet-Desnoyers, Gwenn, Guzman, Monica L., Talpaz, Moshe, Bixby, Dale L., Sun, Duxin, Hess, Jay L., Muntean, Andrew G., Maillard, Ivan, Cierpicki, Tomasz, & Grembecka, Jolanta. Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo. United States. doi:10.1016/j.ccell.2015.02.016.
Borkin, Dmitry, He, Shihan, Miao, Hongzhi, Kempinska, Katarzyna, Pollock, Jonathan, Chase, Jennifer, Purohit, Trupta, Malik, Bhavna, Zhao, Ting, Wang, Jingya, Wen, Bo, Zong, Hongliang, Jones, Morgan, Danet-Desnoyers, Gwenn, Guzman, Monica L., Talpaz, Moshe, Bixby, Dale L., Sun, Duxin, Hess, Jay L., Muntean, Andrew G., Maillard, Ivan, Cierpicki, Tomasz, and Grembecka, Jolanta. Wed . "Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo". United States. doi:10.1016/j.ccell.2015.02.016.
@article{osti_1497151,
title = {Pharmacologic Inhibition of the Menin-MLL Interaction Blocks Progression of MLL Leukemia In Vivo},
author = {Borkin, Dmitry and He, Shihan and Miao, Hongzhi and Kempinska, Katarzyna and Pollock, Jonathan and Chase, Jennifer and Purohit, Trupta and Malik, Bhavna and Zhao, Ting and Wang, Jingya and Wen, Bo and Zong, Hongliang and Jones, Morgan and Danet-Desnoyers, Gwenn and Guzman, Monica L. and Talpaz, Moshe and Bixby, Dale L. and Sun, Duxin and Hess, Jay L. and Muntean, Andrew G. and Maillard, Ivan and Cierpicki, Tomasz and Grembecka, Jolanta},
abstractNote = {},
doi = {10.1016/j.ccell.2015.02.016},
journal = {Cancer Cell},
issn = {1535-6108},
number = 4,
volume = 27,
place = {United States},
year = {2015},
month = {4}
}

Works referencing / citing this record:

Design of the First-in-Class, Highly Potent Irreversible Inhibitor Targeting the Menin-MLL Protein-Protein Interaction
journal, January 2018

  • Xu, Shilin; Aguilar, Angelo; Xu, Tianfeng
  • Angewandte Chemie International Edition, Vol. 57, Issue 6
  • DOI: 10.1002/anie.201711828

Functional diversity of inhibitors tackling the differentiation blockage of MLL-rearranged leukemia
journal, June 2019

  • Brzezinka, Krzysztof; Nevedomskaya, Ekaterina; Lesche, Ralf
  • Journal of Hematology & Oncology, Vol. 12, Issue 1
  • DOI: 10.1186/s13045-019-0749-y

Modes of Interaction of KMT2 Histone H3 Lysine 4 Methyltransferase/COMPASS Complexes with Chromatin
journal, March 2018

  • Bochyńska, Agnieszka; Lüscher-Firzlaff, Juliane; Lüscher, Bernhard
  • Cells, Vol. 7, Issue 3
  • DOI: 10.3390/cells7030017