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Title: A combination therapy for KRAS-driven lung adenocarcinomas using lipophilic bisphosphonates and rapamycin

Journal Article · · Science Translational Medicine
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Research Organization:
Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Organization:
USDOE Office of Science (SC)
OSTI ID:
1497145
Journal Information:
Science Translational Medicine, Vol. 6, Issue 263; ISSN 1946-6234
Publisher:
AAAS
Country of Publication:
United States
Language:
ENGLISH

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Cited By (8)

Polyoxomolybdate Bisphosphonate Heterometallic Complexes: Synthesis, Structure, and Activity on a Breast Cancer Cell Line journal June 2015
mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer journal August 2018
Targeting prenylation inhibition through the mevalonate pathway journal January 2020
KRAS: A Promising Therapeutic Target for Cancer Treatment journal November 2019
Combining Vγ9Vδ2 T Cells with a Lipophilic Bisphosphonate Efficiently Kills Activated Hepatic Stellate Cells journal October 2017
Role of Autophagy and Apoptosis in Non-Small-Cell Lung Cancer journal February 2017
mTOR mediates a mechanism of resistance to chemotherapy and defines a rational combination strategy to treat KRAS-mutant lung cancer. text January 2019
The Antitumor Effect of Lipophilic Bisphosphonate BPH1222 in Melanoma Models: The Role of the PI3K/Akt Pathway and the Small G Protein Rheb journal October 2019

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