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Title: Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design

Authors:
 [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1];  [1]
  1. Cancer Chemistry, ‡PDM, and §Oncology Research Unit, Pfizer Worldwide Research and Development, La Jolla Laboratories, 10770 Science Center Drive, San Diego, California 92121, United States
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
INDUSTRY
OSTI Identifier:
1495455
Resource Type:
Journal Article
Journal Name:
ACS Medicinal Chemistry Letters
Additional Journal Information:
Journal Volume: 4; Journal Issue: 1; Journal ID: ISSN 1948-5875
Publisher:
American Chemical Society (ACS)
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Cheng, Hengmiao, Li, Chunze, Bailey, Simon, Baxi, Sangita M., Goulet, Lance, Guo, Lisa, Hoffman, Jacqui, Jiang, Ying, Johnson, Theodore Otto, Johnson, Ted W., Knighton, Daniel R., Li, John, Liu, Kevin K. -C., Liu, Zhengyu, Marx, Matthew A., Walls, Marlena, Wells, Peter A., Yin, Min-Jean, Zhu, Jinjiang, and Zientek, Michael. Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. United States: N. p., 2012. Web. doi:10.1021/ml300309h.
Cheng, Hengmiao, Li, Chunze, Bailey, Simon, Baxi, Sangita M., Goulet, Lance, Guo, Lisa, Hoffman, Jacqui, Jiang, Ying, Johnson, Theodore Otto, Johnson, Ted W., Knighton, Daniel R., Li, John, Liu, Kevin K. -C., Liu, Zhengyu, Marx, Matthew A., Walls, Marlena, Wells, Peter A., Yin, Min-Jean, Zhu, Jinjiang, & Zientek, Michael. Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design. United States. doi:10.1021/ml300309h.
Cheng, Hengmiao, Li, Chunze, Bailey, Simon, Baxi, Sangita M., Goulet, Lance, Guo, Lisa, Hoffman, Jacqui, Jiang, Ying, Johnson, Theodore Otto, Johnson, Ted W., Knighton, Daniel R., Li, John, Liu, Kevin K. -C., Liu, Zhengyu, Marx, Matthew A., Walls, Marlena, Wells, Peter A., Yin, Min-Jean, Zhu, Jinjiang, and Zientek, Michael. Fri . "Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design". United States. doi:10.1021/ml300309h.
@article{osti_1495455,
title = {Discovery of the Highly Potent PI3K/mTOR Dual Inhibitor PF-04979064 through Structure-Based Drug Design},
author = {Cheng, Hengmiao and Li, Chunze and Bailey, Simon and Baxi, Sangita M. and Goulet, Lance and Guo, Lisa and Hoffman, Jacqui and Jiang, Ying and Johnson, Theodore Otto and Johnson, Ted W. and Knighton, Daniel R. and Li, John and Liu, Kevin K. -C. and Liu, Zhengyu and Marx, Matthew A. and Walls, Marlena and Wells, Peter A. and Yin, Min-Jean and Zhu, Jinjiang and Zientek, Michael},
abstractNote = {},
doi = {10.1021/ml300309h},
journal = {ACS Medicinal Chemistry Letters},
issn = {1948-5875},
number = 1,
volume = 4,
place = {United States},
year = {2012},
month = {11}
}