skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Bioactive compositions for high avidity cell capture

Abstract

A composition useful for cell capture, the composition comprising a solid substrate on which is affixed a patterned polymer, and a cell-targeting agent attached to said patterned polymer, wherein said cell-targeting agent is exposed. Also described is a method for the preparation of the cell capturing composition, as well as flow through devices in which the cell capturing composition is incorporated. Further described is a method of capturing cells by contacting the cell-capturing composition with a liquid or gaseous sample containing cells. The method for capturing cells may also be a method for testing for the presence of one or more classes or species of cells or cellular organisms in a liquid or gaseous sample.

Inventors:
; ; ; ; ; ; ;
Publication Date:
Research Org.:
Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1494583
Patent Number(s):
10,131,899
Application Number:
14/215,552
Assignee:
UT-BATTELLE, LLC (Oak Ridge, TN) ORNL
DOE Contract Number:  
AC05-00OR22725
Resource Type:
Patent
Resource Relation:
Patent File Date: 2014 Mar 17
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Hansen, Ryan Robert, Retterer, Scott T., Lokitz, Bradley Steward, Morrell-Falvey, Jennifer L., Salazar, Juan Pablo Hinestrosa, Messman, Jamie Michael, Kilbey, II, Sidney Michael, and Ankner, John Francis. Bioactive compositions for high avidity cell capture. United States: N. p., 2018. Web.
Hansen, Ryan Robert, Retterer, Scott T., Lokitz, Bradley Steward, Morrell-Falvey, Jennifer L., Salazar, Juan Pablo Hinestrosa, Messman, Jamie Michael, Kilbey, II, Sidney Michael, & Ankner, John Francis. Bioactive compositions for high avidity cell capture. United States.
Hansen, Ryan Robert, Retterer, Scott T., Lokitz, Bradley Steward, Morrell-Falvey, Jennifer L., Salazar, Juan Pablo Hinestrosa, Messman, Jamie Michael, Kilbey, II, Sidney Michael, and Ankner, John Francis. Tue . "Bioactive compositions for high avidity cell capture". United States. https://www.osti.gov/servlets/purl/1494583.
@article{osti_1494583,
title = {Bioactive compositions for high avidity cell capture},
author = {Hansen, Ryan Robert and Retterer, Scott T. and Lokitz, Bradley Steward and Morrell-Falvey, Jennifer L. and Salazar, Juan Pablo Hinestrosa and Messman, Jamie Michael and Kilbey, II, Sidney Michael and Ankner, John Francis},
abstractNote = {A composition useful for cell capture, the composition comprising a solid substrate on which is affixed a patterned polymer, and a cell-targeting agent attached to said patterned polymer, wherein said cell-targeting agent is exposed. Also described is a method for the preparation of the cell capturing composition, as well as flow through devices in which the cell capturing composition is incorporated. Further described is a method of capturing cells by contacting the cell-capturing composition with a liquid or gaseous sample containing cells. The method for capturing cells may also be a method for testing for the presence of one or more classes or species of cells or cellular organisms in a liquid or gaseous sample.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {2018},
month = {11}
}

Patent:

Save / Share: