The role of metals in mammalian olfaction of low molecular weight organosulfur compounds
Abstract
While suggestions concerning the possible role of metals in olfaction and taste date back 50 years, only recently has it been possible to confirm these proposals with experiments involving individual olfactory receptors (ORs). A detailed discussion of recent experimental results demonstrating the key role of metals in enhancing the response of human and other vertebrate ORs to specific odorants is presented against the backdrop of our knowledge of how the sense of smell functions both at the molecular and whole animal levels. This review emphasizes the role of metals in the detection of low molecular weight thiols, sulfides, and other organosulfur compounds, including those found in strong-smelling animal excretions and plant volatiles, and those used in gas odorization. Alternative theories of olfaction are described, with evidence favoring the modified “shape” theory. The use of quantum mechanical/molecular modeling (QM/MM), site-directed mutagenesis and saturation-transfer-difference (STD) NMR is discussed, providing support for biological studies of mouse and human receptors, MOR244-3 and OR OR2T11, respectively. Copper is bound at the active site of MOR244-3 by cysteine and histidine, while cysteine, histidine and methionine are involved with OR2T11. The binding pockets of these two receptors are found in different locations in the three-dimensional seven transmembranemore »
- Authors:
-
[1];
[2];
[3];
[4];
[2]
- Department of Chemistry; University at Albany; State University of New York; Albany; USA
- Department of Chemistry; Yale University; New Haven; USA
- Department of Molecular Genetics and Microbiology; Department of Neurobiology; Duke Institute for Brain Sciences; Duke University Medical Center; Durham
- Institutes of Health Sciences; Shanghai Jiaotong University School of Medicine; Shanghai Institutes for Biological Science of Chinese Academy of Sciences; Shanghai 200031; China
- Publication Date:
- Research Org.:
- Lawrence Berkeley National Laboratory-National Energy Research Scientific Computing Center
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1492957
- Resource Type:
- Journal Article
- Journal Name:
- Natural Product Reports
- Additional Journal Information:
- Journal Volume: 34; Journal Issue: 5; Journal ID: ISSN 0265-0568
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Block, Eric, Batista, Victor S., Matsunami, Hiroaki, Zhuang, Hanyi, and Ahmed, Lucky. The role of metals in mammalian olfaction of low molecular weight organosulfur compounds. United States: N. p., 2017.
Web. doi:10.1039/c7np00016b.
Block, Eric, Batista, Victor S., Matsunami, Hiroaki, Zhuang, Hanyi, & Ahmed, Lucky. The role of metals in mammalian olfaction of low molecular weight organosulfur compounds. United States. doi:10.1039/c7np00016b.
Block, Eric, Batista, Victor S., Matsunami, Hiroaki, Zhuang, Hanyi, and Ahmed, Lucky. Sun .
"The role of metals in mammalian olfaction of low molecular weight organosulfur compounds". United States. doi:10.1039/c7np00016b.
@article{osti_1492957,
title = {The role of metals in mammalian olfaction of low molecular weight organosulfur compounds},
author = {Block, Eric and Batista, Victor S. and Matsunami, Hiroaki and Zhuang, Hanyi and Ahmed, Lucky},
abstractNote = {While suggestions concerning the possible role of metals in olfaction and taste date back 50 years, only recently has it been possible to confirm these proposals with experiments involving individual olfactory receptors (ORs). A detailed discussion of recent experimental results demonstrating the key role of metals in enhancing the response of human and other vertebrate ORs to specific odorants is presented against the backdrop of our knowledge of how the sense of smell functions both at the molecular and whole animal levels. This review emphasizes the role of metals in the detection of low molecular weight thiols, sulfides, and other organosulfur compounds, including those found in strong-smelling animal excretions and plant volatiles, and those used in gas odorization. Alternative theories of olfaction are described, with evidence favoring the modified “shape” theory. The use of quantum mechanical/molecular modeling (QM/MM), site-directed mutagenesis and saturation-transfer-difference (STD) NMR is discussed, providing support for biological studies of mouse and human receptors, MOR244-3 and OR OR2T11, respectively. Copper is bound at the active site of MOR244-3 by cysteine and histidine, while cysteine, histidine and methionine are involved with OR2T11. The binding pockets of these two receptors are found in different locations in the three-dimensional seven transmembrane models. Another recently deorphaned human olfactory receptor, OR2M3, highly selective for a thiol from onions, and a broadly-tuned thiol receptor, OR1A1, are also discussed. Other topics covered include the effects of nanoparticles and heavy metal toxicants on vertebrate and fish ORs, intranasal zinc products and the loss of smell (anosmia).},
doi = {10.1039/c7np00016b},
journal = {Natural Product Reports},
issn = {0265-0568},
number = 5,
volume = 34,
place = {United States},
year = {2017},
month = {1}
}
DOI: 10.1039/c7np00016b
Other availability
Find in Google Scholar
Search WorldCat to find libraries that may hold this journal
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Olfactory perception of chemically diverse molecules
journal, August 2016
- Keller, Andreas; Vosshall, Leslie B.
- BMC Neuroscience, Vol. 17, Issue 1
The role of flavor and fragrance chemicals in TRPA1 (transient receptor potential cation channel, member A1) activity associated with allergies
journal, March 2015
- Mihara, Satoru; Shibamoto, Takayuki
- Allergy, Asthma & Clinical Immunology, Vol. 11, Issue 1
A Large-Scale Analysis of Odor Coding in the Olfactory Epithelium
journal, June 2011
- Nara, K.; Saraiva, L. R.; Ye, X.
- Journal of Neuroscience, Vol. 31, Issue 25
Direct nuclear magnetic resonance observation of odorant binding to mouse odorant receptor MOR244-3
journal, June 2016
- Burger, Jessica L.; Jeerage, Kavita M.; Bruno, Thomas J.
- Analytical Biochemistry, Vol. 502
Persistent anosmia following zinc sulfate nasal spraying
journal, July 1938
- Tisdall, F. F.; Brown, Alan; Defries, R. D.
- The Journal of Pediatrics, Vol. 13, Issue 1
Tyrosinase Catalyzes Asymmetric Sulfoxidation †
journal, March 2008
- Pievo, Roberta; Gullotti, Michele; Monzani, Enrico
- Biochemistry, Vol. 47, Issue 11
The Structural Basis of G-Protein-Coupled Receptor Signaling (Nobel Lecture)
journal, May 2013
- Kobilka, Brian
- Angewandte Chemie International Edition, Vol. 52, Issue 25
Odor Coding by a Mammalian Receptor Repertoire
journal, March 2009
- Saito, H.; Chi, Q.; Zhuang, H.
- Science Signaling, Vol. 2, Issue 60
Efficient cell-free production of olfactory receptors: Detergent optimization, structure, and ligand binding analyses
journal, October 2008
- Kaiser, L.; Graveland-Bikker, J.; Steuerwald, D.
- Proceedings of the National Academy of Sciences, Vol. 105, Issue 41
Dimethyl sulphide as a foraging cue for Antarctic Procellariiform seabirds
journal, August 1995
- Nevitt, Gabrielle A.; Veit, Richard R.; Kareiva, Peter
- Nature, Vol. 376, Issue 6542
Behavioral Responses of CD-1 Mice to Six Predator Odor Components
journal, February 2016
- Sievert, Thorbjörn; Laska, Matthias
- Chemical Senses, Vol. 41, Issue 5
Encoding social signals in the mouse main olfactory bulb
journal, February 2005
- Lin, Da Yu; Zhang, Shao-Zhong; Block, Eric
- Nature, Vol. 434, Issue 7032
Differential response of olfactory sensory neuron populations to copper ion exposure in zebrafish
journal, February 2017
- Lazzari, Maurizio; Bettini, Simone; Milani, Liliana
- Aquatic Toxicology, Vol. 183
A psychophysical test of the vibration theory of olfaction
journal, March 2004
- Keller, Andreas; Vosshall, Leslie B.
- Nature Neuroscience, Vol. 7, Issue 4
The Enantioselectivity of Odor Sensation: Some Examples for Undergraduate Chemistry Courses
journal, June 2010
- Kraft, Philip; Mannschreck, Albrecht
- Journal of Chemical Education, Vol. 87, Issue 6
The Nature of the Intermolecular Forces Operative in Biological Processes
journal, July 1940
- Pauling, L.; Delbruck, M.
- Science, Vol. 92, Issue 2378
Zinc and copper in human cerebrospinal fluid
journal, June 1982
- Agarwal, R. P.; Henkin, R. I.
- Biological Trace Element Research, Vol. 4, Issue 2-3
Intranasal exposure to manganese disrupts neurotransmitter release from glutamatergic synapses in the central nervous system in vivo
journal, October 2012
- Moberly, Andrew H.; Czarnecki, Lindsey A.; Pottackal, Joseph
- NeuroToxicology, Vol. 33, Issue 5
RTP Family Members Induce Functional Expression of Mammalian Odorant Receptors
journal, November 2004
- Saito, Harumi; Kubota, Momoka; Roberts, Richard W.
- Cell, Vol. 119, Issue 5
After oxidation, zinc nanoparticles lose their ability to enhance responses to odorants
journal, September 2016
- Hagerty, Samantha; Daniels, Yasmine; Singletary, Melissa
- BioMetals, Vol. 29, Issue 6
Single-Electron Transfer between CuX 2 and Thiols Determined by Extended X-Ray Absorption Fine Structure Analysis: Application in Markovnikov-Type Hydrothiolation of Styrenes
journal, November 2016
- Yi, Hong; Song, Chunlan; Li, Yiying
- Chemistry - A European Journal, Vol. 22, Issue 51
A Mass Transport Model of Olfaction
journal, March 1994
- Hahn, Intaek; Scherer, Peter W.; Mozell, Maxwell M.
- Journal of Theoretical Biology, Vol. 167, Issue 2
Enhanced activation of the transient receptor potential channel TRPA1 by ajoene, an allicin derivative
journal, January 2010
- Yassaka, Ricardo Tsuneo; Inagaki, Hidetoshi; Fujino, Tsuchiyoshi
- Neuroscience Research, Vol. 66, Issue 1
Applications of Direct Analysis in Real Time−Mass Spectrometry (DART-MS) in Allium Chemistry. ( Z )-Butanethial S -Oxide and 1-Butenyl Thiosulfinates and Their S -( E )-1-Butenylcysteine S -Oxide Precursor from Allium siculum
journal, January 2010
- Kubec, Roman; Cody, Robert B.; Dane, A. John
- Journal of Agricultural and Food Chemistry, Vol. 58, Issue 2
Molecular vibration-sensing component in Drosophila melanogaster olfaction
journal, February 2011
- Franco, Maria Isabel; Turin, Luca; Mershin, Andreas
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 9
Enhancement of Odorant-Induced Responses in Olfactory Receptor Neurons by Zinc Nanoparticles
journal, June 2009
- Viswaprakash, N.; Dennis, J. C.; Globa, L.
- Chemical Senses, Vol. 34, Issue 7
Exudation of low molecular weight compounds (thiobismethane, methyl isocyanide, and methyl isothiocyanate) as a possible chemical defense mechanism in the marine sponge Ircinia felix
journal, May 2001
- Duque, Carmenza; Bonilla, Adriana; Bautista, Edgar
- Biochemical Systematics and Ecology, Vol. 29, Issue 5
Bioinorganic Life and Neural Activity: Toward a Chemistry of Consciousness?
journal, March 2017
- Chang, Christopher J.
- Accounts of Chemical Research, Vol. 50, Issue 3
Impaired behavioural response to alarm substance in rainbow trout exposed to copper nanoparticles
journal, July 2014
- Sovová, Tereza; Boyle, David; Sloman, Katherine A.
- Aquatic Toxicology, Vol. 152
Odor and molecular vibration: Neural coding of olfactory information
journal, February 1977
- Wright, R. H.
- Journal of Theoretical Biology, Vol. 64, Issue 3
Crucial role of copper in detection of metal-coordinating odorants
journal, February 2012
- Duan, X.; Block, E.; Li, Z.
- Proceedings of the National Academy of Sciences, Vol. 109, Issue 9
Combinatorial Receptor Codes for Odors
journal, March 1999
- Malnic, Bettina; Hirono, Junzo; Sato, Takaaki
- Cell, Vol. 96, Issue 5
Synthetic equivalents of benzenethiol and benzyl mercaptan having faint smell: odor reducing effect of trialkylsilyl group
journal, November 2002
- Nishide, Kiyoharu; Miyamoto, Tetsuo; Kumar, Kamal
- Tetrahedron Letters, Vol. 43, Issue 47
Inflorescence Odour of the Foul-Smelling Aroid Helicodiceros muscivorus
journal, January 2000
- Kite, Geoffrey C.
- Kew Bulletin, Vol. 55, Issue 1
Rotting smell of dead-horse arum florets
journal, December 2002
- Stensmyr, Marcus C.; Urru, Isabella; Collu, Ignazio
- Nature, Vol. 420, Issue 6916
Simplifying the Odor Landscape
journal, February 2017
- Trimmer, Casey; Mainland, Joel D.
- Chemical Senses, Vol. 42, Issue 3
Zinc nanoparticles interact with olfactory receptor neurons
journal, June 2010
- Vodyanoy, Vitaly
- BioMetals, Vol. 23, Issue 6
Olfactory Discrimination Ability of Asian Elephants (Elephas maximus) for Structurally Related Odorants
journal, December 2012
- Rizvanovic, A.; Amundin, M.; Laska, M.
- Chemical Senses, Vol. 38, Issue 2
Nanoparticle-based paper sensor for thiols evaluation in human skin
journal, April 2017
- Markina, M.; Stozhko, N.; Krylov, V.
- Talanta, Vol. 165
Structural insights into µ-opioid receptor activation
journal, August 2015
- Huang, Weijiao; Manglik, Aashish; Venkatakrishnan, A. J.
- Nature, Vol. 524, Issue 7565
Optical Imaging of Odorant Representations in the Mammalian Olfactory Bulb
journal, July 1999
- Rubin, Benjamin D.; Katz, Lawrence C.
- Neuron, Vol. 23, Issue 3
Ligand Specificity and Evolution of Mammalian Musk Odor Receptors: Effect of Single Receptor Deletion on Odor Detection
journal, April 2016
- Sato-Akuhara, N.; Horio, N.; Kato-Namba, A.
- Journal of Neuroscience, Vol. 36, Issue 16
A common inhibitory binding site for zinc and odorants at the voltage-gated K + channel of rat olfactory receptor neurons : A common binding site for zinc and odorants
journal, July 2001
- Seebungkert, Benchamaporn; Lynch, Joseph W.
- European Journal of Neuroscience, Vol. 14, Issue 2
Intranasal Zinc and Anosmia: The Zinc-Induced Anosmia Syndrome
journal, January 2006
- Alexander, Thomas H.; Davidson, Terence M.
- The Laryngoscope, Vol. 116, Issue 2
Olfactory sensitivity for putrefaction-associated thiols and indols in three species of non-human primate
journal, December 2007
- Laska, M.; Bautista, R. M. R.; Hofelmann, D.
- Journal of Experimental Biology, Vol. 210, Issue 23
The main and the accessory olfactory systems interact in the control of mate recognition and sexual behavior
journal, June 2009
- Keller, Matthieu; Baum, Michael J.; Brock, Olivier
- Behavioural Brain Research, Vol. 200, Issue 2
Metal Ion Enhanced Binding of AMD3100 to Asp 262 in the CXCR4 Receptor †
journal, January 2003
- Gerlach, Lars Ole; Jakobsen, Janus S.; Jensen, Kasper P.
- Biochemistry, Vol. 42, Issue 3
Differential Electrophysiological Responses to Odorant Isotopologues in Drosophilid Antennae
journal, May 2016
- Drimyli, Efstathia; Gaitanidis, Alexandros; Maniati, Klio
- eneuro, Vol. 3, Issue 3
Synthesis and studies of Cu(II)-thiolato complexes: bioinorganic perspectives
journal, April 1997
- Mandal, Subrata; Das, Gopal; Singh, Ramsharan
- Coordination Chemistry Reviews, Vol. 160
Truffle volatiles: from chemical ecology to aroma biosynthesis: Research review
journal, November 2010
- Splivallo, Richard; Ottonello, Simone; Mello, Antonietta
- New Phytologist, Vol. 189, Issue 3
A Spectroscopic Mechanism for Primary Olfactory Reception
journal, January 1996
- Turin, Luca
- Chemical Senses, Vol. 21, Issue 6
Laying a controversial smell theory to rest
journal, May 2015
- Vosshall, Leslie B.
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 21
Effects of inorganic mercury on the olfactory pits of zebrafish larvae
journal, January 2016
- MacDonald, Tracy C.; Sylvain, Nicole J.; James, Ashley K.
- Metallomics, Vol. 8, Issue 5
A colorimetric sensor array for odour visualization
journal, August 2000
- Rakow, Neal A.; Suslick, Kenneth S.
- Nature, Vol. 406, Issue 6797
Introduction: G-Protein Coupled Receptors
journal, June 2016
- Sakmar, Thomas P.
- Chemical Reviews, Vol. 117, Issue 1
Modulation of μ1, μ2, and δ opioid binding by divalent cations
journal, July 1990
- Kinouchi, Keiko; Standifer, Kelly M.; Pasternak, Gavril W.
- Biochemical Pharmacology, Vol. 40, Issue 2
The Sulfur Chemistry of Shiitake Mushroom
journal, January 2004
- Sneeden, Eileen Yu; Harris, Hugh H.; Pickering, Ingrid J.
- Journal of the American Chemical Society, Vol. 126, Issue 2
A review of volatile sulfur-containing compounds from terrestrial plants: biosynthesis, distribution and analytical methods
journal, August 2012
- Iranshahi, M.
- Journal of Essential Oil Research, Vol. 24, Issue 4
Perireceptor and receptor events in vertebrate olfaction
journal, January 1984
- Getchell, T.; Margolis, F.; Getchell, M.
- Progress in Neurobiology, Vol. 23, Issue 4
Applications of Direct Analysis in Real Time Mass Spectrometry (DART-MS) in Allium Chemistry. 2-Propenesulfenic and 2-Propenesulfinic Acids, Diallyl Trisulfane S -Oxide, and Other Reactive Sulfur Compounds from Crushed Garlic and Other Alliums
journal, April 2010
- Block, Eric; Dane, A. John; Thomas, Siji
- Journal of Agricultural and Food Chemistry, Vol. 58, Issue 8
Floral scent in bat-pollinated plants: a case of convergent evolution
journal, September 1995
- Knudsen, Jette T.; Tollsten, Lars
- Botanical Journal of the Linnean Society, Vol. 119, Issue 1
Assessing the Impact of Anosmia: Review of a Questionnaire's Findings
journal, December 1999
- Toller, S. V.
- Chemical Senses, Vol. 24, Issue 6
Social Signals: The Secret Language of Mice
journal, April 2005
- Vosshall, Leslie B.
- Current Biology, Vol. 15, Issue 7
Evidence for a Chromatographic Model of Olfaction
journal, July 1970
- Mozell, M. M.
- The Journal of General Physiology, Vol. 56, Issue 1
Metal Ion-mediated Agonism and Agonist Enhancement in Melanocortin MC1 and MC4 Receptors
journal, September 2002
- Holst, Birgitte; Elling, Christian E.; Schwartz, Thue W.
- Journal of Biological Chemistry, Vol. 277, Issue 49
Enhancement of Odor-Induced Activity in the Canine Brain by Zinc Nanoparticles: A Functional MRI Study in Fully Unrestrained Conscious Dogs
journal, October 2015
- Jia, Hao; Pustovyy, Oleg M.; Wang, Yun
- Chemical Senses, Vol. 41, Issue 1
Expression of human olfactory receptor 10J5 in heart aorta, coronary artery, and endothelial cells and its functional role in angiogenesis
journal, May 2015
- Kim, Sung-Hee; Yoon, Yeo Cho; Lee, Ae Sin
- Biochemical and Biophysical Research Communications, Vol. 460, Issue 2
The lachrymatory principle of Petiveria alliacea
journal, May 2003
- Kubec, Roman; Kim, Seokwon; Musah, Rabi A.
- Phytochemistry, Vol. 63, Issue 1
Sulphur-containing "perfumes" attract flower-visiting bats
journal, February 2000
- von Helversen, O.; Winkler, L.; Bestmann, H. J.
- Journal of Comparative Physiology A: Sensory, Neural, and Behavioral Physiology, Vol. 186, Issue 2
Sensing Odorants and Pheromones with Chemosensory Receptors
journal, March 2009
- Touhara, Kazushige; Vosshall, Leslie B.
- Annual Review of Physiology, Vol. 71, Issue 1
Copper Binding Dynamics and Olfactory Impairment in Fathead Minnows ( Pimephales promelas )
journal, February 2010
- Green, Warren W.; Mirza, Reehan S.; Wood, Chris M.
- Environmental Science & Technology, Vol. 44, Issue 4
A Randomized, Placebo Controlled Trial of Oral Zinc for Chemotherapy-Related Taste and Smell Disorders
journal, June 2012
- Lyckholm, Laurel; Heddinger, Steven P.; Parker, Gwendolyn
- Journal of Pain & Palliative Care Pharmacotherapy, Vol. 26, Issue 2
Chaperone-mediated copper handling in the periplasm
journal, January 2010
- Kim, Eun-Hae; Rensing, Christopher; McEvoy, Megan M.
- Natural Product Reports, Vol. 27, Issue 5
Scents and Sensibility: A Molecular Logic of Olfactory Perception (Nobel Lecture)
journal, September 2005
- Axel, Richard
- Angewandte Chemie International Edition, Vol. 44, Issue 38
Multicomponent Reactions of Convertible Isonitriles
journal, June 2009
- Pirrung, Michael C.; Ghorai, Subir; Ibarra-Rivera, Tannya R.
- The Journal of Organic Chemistry, Vol. 74, Issue 11
Saturation-Transfer Difference (STD) NMR: A Simple and Fast Method for Ligand Screening and Characterization of Protein Binding
journal, July 2011
- Viegas, Aldino; Manso, João; Nobrega, Franklin L.
- Journal of Chemical Education, Vol. 88, Issue 7
The Broadly Tuned Odorant Receptor OR1A1 is Highly Selective for 3-Methyl-2,4-nonanedione, a Key Food Odorant in Aged Wines, Tea, and Other Foods
journal, December 2016
- Geithe, Christiane; Noe, Franziska; Kreissl, Johanna
- Chemical Senses, Vol. 42, Issue 3
Effect of dietary nickel deprivation on vision, olfaction, and taste in rats
journal, October 2014
- Yokoi, Katsuhiko; Uthus, Eric O.; Penland, James G.
- Journal of Trace Elements in Medicine and Biology, Vol. 28, Issue 4
Thioether Coordination Chemistry for Molecular Imaging of Copper in Biological Systems
journal, July 2016
- Ramos-Torres, Karla M.; Kolemen, Safacan; Chang, Christopher J.
- Israel Journal of Chemistry, Vol. 56, Issue 9-10
OR2M3: A Highly Specific and Narrowly Tuned Human Odorant Receptor for the Sensitive Detection of Onion Key Food Odorant 3-Mercapto-2-methylpentan-1-ol
journal, December 2016
- Noe, Franziska; Polster, Johannes; Geithe, Christiane
- Chemical Senses, Vol. 42, Issue 3
Conjugated oxidation of thiols and amines in the presence of copper complexes
journal, August 2010
- Tarkhanova, I. G.; Gantman, M. G.; Chizhov, A. O.
- Reaction Kinetics, Mechanisms and Catalysis, Vol. 101, Issue 2
Insights into Thiol–Aromatic Interactions: A Stereoelectronic Basis for S–H/π Interactions
journal, January 2017
- Forbes, Christina R.; Sinha, Sudipta K.; Ganguly, Himal K.
- Journal of the American Chemical Society, Vol. 139, Issue 5
Odorant Receptor Map in the Mouse Olfactory Bulb: In Vivo Sensitivity and Specificity of Receptor-Defined Glomeruli
journal, December 2006
- Oka, Yuki; Katada, Sayako; Omura, Masayo
- Neuron, Vol. 52, Issue 5
Olfaction: New Understandings, Diagnostic Applications
journal, November 2016
- Ruggiero, GabrielleF.; Wick, JeannetteY.
- The Consultant Pharmacist, Vol. 31, Issue 11
Zinc released from olfactory bulb glomeruli by patterned electrical stimulation of the olfactory nerve
journal, January 2013
- Blakemore, Laura J.; Tomat, Elisa; Lippard, Stephen J.
- Metallomics, Vol. 5, Issue 3
Evidence that dimethyl sulfide facilitates a tritrophic mutualism between marine primary producers and top predators
journal, March 2014
- Savoca, M. S.; Nevitt, G. A.
- Proceedings of the National Academy of Sciences, Vol. 111, Issue 11
Decreased Taste Sensitivity After D-Penicillamine Reversed by Copper Administration
journal, December 1967
- Henkin, RobertI.; Keiser, HarryR.; Jaffe, IsraeliA.
- The Lancet, Vol. 290, Issue 7529
Kinetic Model for the Activation of Mammalian Olfactory Receptor
journal, February 2017
- Jang, Seogjoo; Hyeon, Changbong
- The Journal of Physical Chemistry B, Vol. 121, Issue 6
A novel cysteine desulfurase influencing organosulfur compounds in Lentinula edodes
journal, June 2015
- Liu, Ying; Lei, Xiao-Yu; Chen, Lian-Fu
- Scientific Reports, Vol. 5, Issue 1
Structure–Odor Activity Studies on Monoterpenoid Mercaptans Synthesized by Changing the Structural Motifs of the Key Food Odorant 1- p -Menthene-8-thiol
journal, May 2016
- Schoenauer, Sebastian; Schieberle, Peter
- Journal of Agricultural and Food Chemistry, Vol. 64, Issue 19
How the olfactory system makes sense of scents
journal, September 2001
- Firestein, Stuart
- Nature, Vol. 413, Issue 6852
The missing stink: sulphur compounds can mediate a shift between fly and wasp pollination systems
journal, April 2010
- Shuttleworth, Adam; Johnson, Steven D.
- Proceedings of the Royal Society B: Biological Sciences, Vol. 277, Issue 1695
Olfactory discrimination ability of CD-1 mice for a large array of enantiomers
journal, January 2007
- Laska, M.; Shepherd, G. M.
- Neuroscience, Vol. 144, Issue 1
Presence of Sex Steroid-Metabolizing Enzymes in the Olfactory Mucosa of Rats: SEX STEROID-METABOLIZING ENZYMES IN THE RAT OLFACTORY MUCOSA
journal, October 2016
- Horie, Sawa; Yamaki, Akiko; Takami, Shigeru
- The Anatomical Record, Vol. 300, Issue 2
Molecular Vibration-Sensing Component in Human Olfaction
journal, January 2013
- Gane, Simon; Georganakis, Dimitris; Maniati, Klio
- PLoS ONE, Vol. 8, Issue 1
Olfactory responses to explosives associated odorants are enhanced by zinc nanoparticles
journal, January 2012
- Moore, Christopher H.; Pustovyy, Oleg; Dennis, John C.
- Talanta, Vol. 88
Predicting human olfactory perception from chemical features of odor molecules
journal, February 2017
- Keller, Andreas; Gerkin, Richard C.; Guan, Yuanfang
- Science, Vol. 355, Issue 6327
Molecular Organization of the Olfactory Septal Organ
journal, September 2004
- Tian, H.
- Journal of Neuroscience, Vol. 24, Issue 38
Enzymatic Conversion of Odorants in Nasal Mucus Affects Olfactory Glomerular Activation Patterns and Odor Perception
journal, December 2010
- Nagashima, A.; Touhara, K.
- Journal of Neuroscience, Vol. 30, Issue 48
High olfactory sensitivity for dimethyl sulphide in harbour seals
journal, September 2005
- Kowalewsky, Sylvia; Dambach, Martin; Mauck, Björn
- Biology Letters, Vol. 2, Issue 1
Quantum origins of molecular recognition and olfaction in drosophila
journal, December 2012
- Bittner, Eric R.; Madalan, Adrian; Czader, Arkadiusz
- The Journal of Chemical Physics, Vol. 137, Issue 22
Biological metals and metal-targeting compounds in major neurodegenerative diseases
journal, January 2014
- Barnham, Kevin J.; Bush, Ashley I.
- Chem. Soc. Rev., Vol. 43, Issue 19
The Organosulfur Chemistry of the GenusAllium - Implications for the Organic Chemistry of Sulfur
journal, September 1992
- Block, Eric
- Angewandte Chemie International Edition in English, Vol. 31, Issue 9
Quantitation of the Intense Aroma Compound 3-Mercapto-2-methylpentan-1-ol in Raw and Processed Onions ( Allium cepa ) of Different Origins and in Other Allium Varieties Using a Stable Isotope Dilution Assay
journal, May 2004
- Granvogl, Michael; Christlbauer, Monika; Schieberle, Peter
- Journal of Agricultural and Food Chemistry, Vol. 52, Issue 10
Multiple profile-multiple receptor site model for vertebrate olfaction
journal, August 1973
- Polak, Ernest H.
- Journal of Theoretical Biology, Vol. 40, Issue 3
Anosmia; or, Cases Illustrating the Physiology and Pathology of the Sense of Smell
journal, January 1870
- Ogle, William
- Journal of the Royal Society of Medicine, Vol. MCT-53, Issue 1
Pungent products from garlic activate the sensory ion channel TRPA1
journal, August 2005
- Bautista, D. M.; Movahed, P.; Hinman, A.
- Proceedings of the National Academy of Sciences, Vol. 102, Issue 34
Olfactory Sensitivity for Six Predator Odorants in CD-1 Mice, Human Subjects, and Spider Monkeys
journal, November 2013
- Sarrafchi, Amir; Odhammer, Anna M. E.; Hernandez Salazar, Laura Teresa
- PLoS ONE, Vol. 8, Issue 11
Mechanosensitivity below Ground: Touch-Sensitive Smell-Producing Roots in the Shy Plant Mimosa pudica
journal, December 2015
- Musah, Rabi A.; Lesiak, Ashton D.; Maron, Max J.
- Plant Physiology, Vol. 170, Issue 2
Plausibility of the vibrational theory of olfaction: Fig. 1.
journal, June 2015
- Turin, Luca; Gane, Simon; Georganakis, Dimitris
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 25
Optical sensor arrays for chemical sensing: the optoelectronic nose
journal, January 2013
- Askim, Jon R.; Mahmoudi, Morteza; Suslick, Kenneth S.
- Chemical Society Reviews, Vol. 42, Issue 22
Association between olfaction and higher cortical functions in Alzheimer’s disease, mild cognitive impairment, and healthy older adults
journal, November 2016
- Ward, Amanda M.; Calamia, Matthew; Thiemann, Erin
- Journal of Clinical and Experimental Neuropsychology, Vol. 39, Issue 7
Unraveling the Sense of Smell (Nobel Lecture)
journal, September 2005
- Buck, Linda B.
- Angewandte Chemie International Edition, Vol. 44, Issue 38
Behavioral attraction of Leach's storm-petrels (Oceanodroma leucorhoa) to dimethyl sulfide
journal, May 2003
- Nevitt, G. A.
- Journal of Experimental Biology, Vol. 206, Issue 9
Silver nanoparticles disrupt olfaction in Crucian carp (Carassius carassius) and Eurasian perch (Perca fluviatilis)
journal, July 2011
- Bilberg, Katrine; Døving, Kjell B.; Beedholm, Kristian
- Aquatic Toxicology, Vol. 104, Issue 1-2
What is so special about smell? Olfaction as a model system in neurobiology
journal, November 2015
- Barwich, Ann-Sophie
- Postgraduate Medical Journal, Vol. 92, Issue 1083
Influence of Coordination Geometry upon Copper(II/I) Redox Potentials. Physical Parameters for Twelve Copper Tripodal Ligand Complexes
journal, September 1999
- Ambundo, Edna A.; Deydier, Marie-Veronique; Grall, Andrew J.
- Inorganic Chemistry, Vol. 38, Issue 19
Assessment of the Aroma Impact of Major Odor-Active Thiols in Pan-Roasted White Sesame Seeds by Calculation of Odor Activity Values
journal, September 2011
- Tamura, Hitoshi; Fujita, Akira; Steinhaus, Martin
- Journal of Agricultural and Food Chemistry, Vol. 59, Issue 18
Spotlight on Varietal Thiols and Precursors in Grapes and Wines
journal, January 2016
- Jeffery, David W.
- Australian Journal of Chemistry, Vol. 69, Issue 12
Odorant Screening and Quantitation of Thiols in Carmenere Red Wine by Gas Chromatography–Olfactometry and Stable Isotope Dilution Assays
journal, April 2016
- Pavez, Carolina; Agosin, Eduardo; Steinhaus, Martin
- Journal of Agricultural and Food Chemistry, Vol. 64, Issue 17
Novel Genetically Encoded Biosensors Using Firefly Luciferase
journal, June 2008
- Fan, Frank; Binkowski, Brock F.; Butler, Braeden L.
- ACS Chemical Biology, Vol. 3, Issue 6
The scientific basis of odour
journal, July 1938
- Malcolm Dyson, G.
- Journal of the Society of Chemical Industry, Vol. 57, Issue 28
Temporal processing of olfactory stimuli during retronasal perception
journal, June 2009
- Wilkes, Fiona J.; Laing, David G.; Hutchinson, Ian
- Behavioural Brain Research, Vol. 200, Issue 1
Synergism of Accessory Factors in Functional Expression of Mammalian Odorant Receptors
journal, March 2007
- Zhuang, Hanyi; Matsunami, Hiroaki
- Journal of Biological Chemistry, Vol. 282, Issue 20
QM/MM Model of the Mouse Olfactory Receptor MOR244-3 Validated by Site-Directed Mutagenesis Experiments
journal, September 2014
- Sekharan, Sivakumar; Ertem, Mehmed Z.; Zhuang, Hanyi
- Biophysical Journal, Vol. 107, Issue 5
Differential Odour Coding of Isotopomers in the Honeybee Brain
journal, February 2016
- Paoli, Marco; Anesi, Andrea; Antolini, Renzo
- Scientific Reports, Vol. 6, Issue 1
The Bradford Hill Criteria and Zinc-Induced Anosmia: A Causality Analysis
journal, July 2010
- Davidson, Terence M.; Smith, Wendy M.
- Archives of Otolaryngology–Head & Neck Surgery, Vol. 136, Issue 7
Volatile thiols in coffee: A review on their formation, degradation, assessment and influence on coffee sensory quality
journal, November 2016
- Dulsat-Serra, Neus; Quintanilla-Casas, Beatriz; Vichi, Stefania
- Food Research International, Vol. 89
The chemical nature of fetid floral odours in stapeliads (Apocynaceae-Asclepiadoideae-Ceropegieae)
journal, November 2006
- Jürgens, Andreas; Dötterl, Stefan; Meve, Ulrich
- New Phytologist, Vol. 172, Issue 3
Metalloprotein design using genetic code expansion
journal, January 2014
- Hu, Cheng; Chan, Sunney I.; Sawyer, Elizabeth B.
- Chem. Soc. Rev., Vol. 43, Issue 18
In Vivo Identification of Eugenol-Responsive and Muscone-Responsive Mouse Odorant Receptors
journal, November 2014
- McClintock, T. S.; Adipietro, K.; Titlow, W. B.
- Journal of Neuroscience, Vol. 34, Issue 47
Sulfur volatiles of microbial origin are key contributors to human-sensed truffle aroma
journal, January 2015
- Splivallo, Richard; Ebeler, Susan E.
- Applied Microbiology and Biotechnology, Vol. 99, Issue 6
Sniffing out significant “Pee values”: genome wide association study of asparagus anosmia
journal, December 2016
- Markt, Sarah C.; Nuttall, Elizabeth; Turman, Constance
- BMJ
Is the olfactory receptor a metalloprotein?
journal, February 2003
- Wang, J.; Luthey-Schulten, Z. A.; Suslick, K. S.
- Proceedings of the National Academy of Sciences, Vol. 100, Issue 6
Does Intranasal Application of Zinc Sulfate Produce Anosmia in the Mouse? An Olfactometric and Anatomical Study
journal, October 2003
- McBride, K.
- Chemical Senses, Vol. 28, Issue 8
Marine plastic debris emits a keystone infochemical for olfactory foraging seabirds
journal, November 2016
- Savoca, Matthew S.; Wohlfeil, Martha E.; Ebeler, Susan E.
- Science Advances, Vol. 2, Issue 11
Synthetic fluorescent probes for studying copper in biological systems
journal, January 2015
- Cotruvo, Jr., Joseph A.; Aron, Allegra T.; Ramos-Torres, Karla M.
- Chemical Society Reviews, Vol. 44, Issue 13
Ueber die Empfindlichkeit des Geruchssinnes;
journal, January 1887
- Fischer, Emil; Penzoldt, Franz
- Justus Liebig's Annalen der Chemie, Vol. 239, Issue 1
Reaction Mechanisms of Metals with Hydrogen Sulfide and Thiols in Model Wine. Part 2: Iron- and Copper-Catalyzed Oxidation
journal, May 2016
- Kreitman, Gal Y.; Danilewicz, John C.; Jeffery, David. W.
- Journal of Agricultural and Food Chemistry, Vol. 64, Issue 20
Sensory systems and ionocytes are targets for silver nanoparticle effects in fish
journal, July 2016
- Osborne, Olivia J.; Mukaigasa, Katsuki; Nakajima, Hitomi
- Nanotoxicology, Vol. 10, Issue 9
Effects of Continuous Copper Exposure and Calcium on the Olfactory Response of Fathead Minnows
journal, July 2012
- Dew, William A.; Wood, Chris M.; Pyle, Greg G.
- Environmental Science & Technology, Vol. 46, Issue 16
From the Cover: Cadmium Exposure Differentially Alters Odorant-Driven Behaviors and Expression of Olfactory Receptors in Juvenile Coho Salmon (Oncorhynchus kisutch)
journal, September 2016
- Williams, Chase R.; MacDonald, James W.; Bammler, Theo K.
- Toxicological Sciences, Vol. 154, Issue 2
Floral scent of bat-pollinated species: West Africa vs. the New World: FLORAL SCENT OF BAT-POLLINATED TREES
journal, June 2004
- Pettersson, Stefan; Ervik, Finn; Knudsen, Jette T.
- Biological Journal of the Linnean Society, Vol. 82, Issue 2
Perireceptor events in olfaction
journal, May 1996
- Pelosi, Paolo
- Journal of Neurobiology, Vol. 30, Issue 1
The missense of smell: functional variability in the human odorant receptor repertoire
journal, December 2013
- Mainland, Joel D.; Keller, Andreas; Li, Yun R.
- Nature Neuroscience, Vol. 17, Issue 1
Dimethyl Sulfide, a Volatile Flavor Constituent, Is a Slow-Binding Inhibitor of Tyrosinase
journal, July 2001
- Pérez-Gilabert, Manuela; Garcı́a-Carmona, Francisco
- Biochemical and Biophysical Research Communications, Vol. 285, Issue 2
Molecular Gastronomy: A New Emerging Scientific Discipline
journal, April 2010
- Barham, Peter; Skibsted, Leif H.; Bredie, Wender L. P.
- Chemical Reviews, Vol. 110, Issue 4
Headspace analysis of volatile flower scent constituents of bat-pollinated plants
journal, December 1997
- Bestmann, Hans Jürgen; Winkler, Lothar; Helversen, Otto von
- Phytochemistry, Vol. 46, Issue 7
Reductive Metalation of Cyclic and Acyclic Pseudopeptidic Bis-Disulfides and Back Conversion of the Resulting Diamidato/Dithiolato Complexes to Bis-Disulfides
journal, September 2010
- Desbenoît, Nicolas; Galardon, Erwan; Frapart, Yves
- Inorganic Chemistry, Vol. 49, Issue 18
Biophysical and functional characterization of the human olfactory receptor OR1A1 expressed in a mammalian inducible cell line
journal, January 2017
- Belloir, Christine; Miller-Leseigneur, Marie-Louise; Neiers, Fabrice
- Protein Expression and Purification, Vol. 129
Dimethyl Trisulfide as a Characteristic Odor Associated with Fungating Cancer Wounds
journal, September 2009
- Shirasu, Mika; Nagai, Shunji; Hayashi, Ryuichi
- Bioscience, Biotechnology, and Biochemistry, Vol. 73, Issue 9
Structure–Activity Relationship Study on Isothiocyanates: Comparison of TRPA1-Activating Ability between Allyl Isothiocyanate and Specific Flavor Components of Wasabi, Horseradish, and White Mustard
journal, July 2015
- Terada, Yuko; Masuda, Hideki; Watanabe, Tatsuo
- Journal of Natural Products, Vol. 78, Issue 8
A Copper Cofactor for the Ethylene Receptor ETR1 from Arabidopsis
journal, February 1999
- Rodriguez, F. I.; Esch, J. J.; Hall, A. E.
- Science, Vol. 283, Issue 5404
Brief exposure to copper induces apoptosis and alters mediators of olfactory signal transduction in coho salmon
journal, November 2013
- Wang, Lu; Espinoza, Herbert M.; Gallagher, Evan P.
- Chemosphere, Vol. 93, Issue 10
A Sensor for Low Environmental Oxygen in the Mouse Main Olfactory Epithelium
journal, December 2016
- Bleymehl, Katherin; Pérez-Gómez, Anabel; Omura, Masayo
- Neuron, Vol. 92, Issue 6
A Family of non-GPCR Chemosensors Defines an Alternative Logic for Mammalian Olfaction
journal, June 2016
- Greer, Paul L.; Bear, Daniel M.; Lassance, Jean-Marc
- Cell, Vol. 165, Issue 7
Dimethyl disulfide and dimethyl trisulfide: so similar yet so different in evoking biological responses in saprophilous flies
journal, August 2014
- Zito, Pietro; Sajeva, Maurizio; Raspi, Alfio
- Chemoecology, Vol. 24, Issue 6
Nature’s Chemical Signatures in Human Olfaction: A Foodborne Perspective for Future Biotechnology
journal, June 2014
- Dunkel, Andreas; Steinhaus, Martin; Kotthoff, Matthias
- Angewandte Chemie International Edition, Vol. 53, Issue 28
Olfactory toxicity in fishes
journal, January 2010
- Tierney, Keith B.; Baldwin, David H.; Hara, Toshiaki J.
- Aquatic Toxicology, Vol. 96, Issue 1
Food Compounds Activating Thermosensitive TRP Channels in Asian Herbal and Medicinal Foods
journal, January 2015
- Watanabe, Tatsuo; Terada, Yuko
- Journal of Nutritional Science and Vitaminology, Vol. 61, Issue Supplement
Sulphur-containing compounds of durian activate the thermogenesis-inducing receptors TRPA1 and TRPV1
journal, August 2014
- Terada, Yuko; Hosono, Takashi; Seki, Taiichiro
- Food Chemistry, Vol. 157
In vivo visualization of olfactory pathophysiology induced by intranasal cadmium instillation in mice
journal, August 2011
- Czarnecki, Lindsey A.; Moberly, Andrew H.; Rubinstein, Tom
- NeuroToxicology, Vol. 32, Issue 4
Structural Insights into the Dynamic Process of β 2 -Adrenergic Receptor Signaling
journal, May 2015
- Manglik, Aashish; Kim, Tae Hun; Masureel, Matthieu
- Cell, Vol. 161, Issue 5
Chemical constituents of the defensive secretion of the striped skunk (Mephitis mephitis)
journal, January 1982
- Andersen, Kenneth K.; Bernstien, David T.; Caret, Robert L.
- Tetrahedron, Vol. 38, Issue 13
Spatial coding of enantiomers in the rat olfactory bulb
journal, April 2001
- Rubin, Benjamin D.; Katz, Lawrence C.
- Nature Neuroscience, Vol. 4, Issue 4
Smell no evil: Copper disrupts the alarm chemical response in a diadromous fish, Galaxias maculatus : Copper disrupts alarm chemical response
journal, May 2016
- Thomas, Oliver R. B.; Barbee, Nicole C.; Hassell, Kathryn L.
- Environmental Toxicology and Chemistry, Vol. 35, Issue 9
Floral scents—a checklist of volatile compounds isolated by head-space techniques
journal, May 1993
- Knudsen, Jette T.; Tollsten, Lars; Bergström, L. Gunnar
- Phytochemistry, Vol. 33, Issue 2
Copper (I): A possible olfactory binding site
journal, January 1978
- Crabtree, Robert H.
- Journal of Inorganic and Nuclear Chemistry, Vol. 40, Issue 7
Reply to Turin et al.: Vibrational theory of olfaction is implausible: Fig. 1.
journal, June 2015
- Block, Eric; Jang, Seogjoo; Matsunami, Hiroaki
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 25
Anosmia: Differential Diagnosis, Evaluation, and Management
journal, January 2017
- Scangas, George A.; Bleier, Benjamin S.
- American Journal of Rhinology & Allergy, Vol. 31, Issue 1
THE INCIDENCE AND PROBABLE INHERITANCE OF “SMELL BLINDNESSrdquo;
journal, October 1948
- Patterson, Paul M.; Lauder, Barbara A.
- Journal of Heredity, Vol. 39, Issue 10
Olfactory receptors in non-chemosensory tissues
journal, November 2012
- Kang, NaNa; Koo, JaeHyung
- BMB Reports, Vol. 45, Issue 11
Floral scent chemistry of mangrove plants
journal, February 2002
- Azuma, H.; Toyota, M.; Asakawa, Y.
- Journal of Plant Research, Vol. 115, Issue 1
Isothiocyanates from Wasabia japonica Activate Transient Receptor Potential Ankyrin 1 Channel
journal, August 2012
- Uchida, Kunitoshi; Miura, Yosuke; Nagai, Masashi
- Chemical Senses, Vol. 37, Issue 9
Occurrence of Odorant Polyfunctional Thiols in Beers Hopped with Different Cultivars. First Evidence of an S -Cysteine Conjugate in Hop (Humulus lupulus L.)
journal, August 2012
- Gros, Jacques; Peeters, Florence; Collin, Sonia
- Journal of Agricultural and Food Chemistry, Vol. 60, Issue 32
Olfactory Receptor and Neural Pathway Responsible for Highly Selective Sensing of Musk Odors
journal, January 2014
- Shirasu, Mika; Yoshikawa, Keiichi; Takai, Yoshiki
- Neuron, Vol. 81, Issue 1
Regulation of Taste Acuity by Thiols and Metal ions
journal, January 1969
- Henkin, R. I.; Bradley, D. F.
- Proceedings of the National Academy of Sciences, Vol. 62, Issue 1
Smelling Sulfur: Copper and Silver Regulate the Response of Human Odorant Receptor OR2T11 to Low-Molecular-Weight Thiols
journal, September 2016
- Li, Shengju; Ahmed, Lucky; Zhang, Ruina
- Journal of the American Chemical Society, Vol. 138, Issue 40
Identification of a Powerful Aroma Compound in Munster and Camembert Cheeses: Ethyl 3-Mercaptopropionate
journal, June 2008
- Sourabié, Alain M.; Spinnler, Henry-Eric; Bonnarme, Pascal
- Journal of Agricultural and Food Chemistry, Vol. 56, Issue 12
Volatile compounds from six species of truffle – head-space analysis and vapor analysis at high mass resolution
journal, March 2006
- March, Raymond E.; Richards, Don S.; Ryan, Robert W.
- International Journal of Mass Spectrometry, Vol. 249-250
Identification and Organoleptic Contribution of Vanillylthiol in Wines
journal, February 2016
- Floch, Morgan; Shinkaruk, Svitlana; Darriet, Philippe
- Journal of Agricultural and Food Chemistry, Vol. 64, Issue 6
Molecular recognition in copper trafficking
journal, January 2010
- Banci, Lucia; Bertini, Ivano; McGreevy, Kathleen S.
- Natural Product Reports, Vol. 27, Issue 5
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
journal, January 2012
- Haga, Kazuko; Kruse, Andrew C.; Asada, Hidetsugu
- Nature, Vol. 482, Issue 7386
Propagation of conformational changes during μ-opioid receptor activation
journal, August 2015
- Sounier, Rémy; Mas, Camille; Steyaert, Jan
- Nature, Vol. 524, Issue 7565
New nitrogen bases with severe steric hindrance due to flanking tert-butyl groups. cis-2,6-Di-tert-butylpiperidine. Possible steric blocking of olfaction
journal, September 1978
- Day, Jack C.
- The Journal of Organic Chemistry, Vol. 43, Issue 19
A Brief History of G-Protein Coupled Receptors (Nobel Lecture)
journal, May 2013
- Lefkowitz, Robert J.
- Angewandte Chemie International Edition, Vol. 52, Issue 25
Mouse alarm pheromone shares structural similarity with predator scents
journal, March 2013
- Brechbuhl, J.; Moine, F.; Klaey, M.
- Proceedings of the National Academy of Sciences, Vol. 110, Issue 12
Processing by the main olfactory system of chemosignals that facilitate mammalian reproduction
journal, February 2015
- Baum, Michael J.; Cherry, James A.
- Hormones and Behavior, Vol. 68
The Importance of Oligosulfides in the Attraction of Fly Pollinators to the Brood-Site Deceptive Species Jaborosa rotacea (Solanaceae)
journal, July 2013
- Moré, Marcela; Cocucci, Andrea A.; Raguso, Robert A.
- International Journal of Plant Sciences, Vol. 174, Issue 6
Insights into the Key Compounds of Durian ( Durio zibethinus L. ‘Monthong’) Pulp Odor by Odorant Quantitation and Aroma Simulation Experiments
journal, January 2017
- Li, Jia-Xiao; Schieberle, Peter; Steinhaus, Martin
- Journal of Agricultural and Food Chemistry, Vol. 65, Issue 3
The variable and conserved interfaces of modeled olfactory receptor proteins
journal, January 1999
- Pilpel, Yitzhak; Lancet, Doron
- Protein Science, Vol. 8, Issue 5
Implausibility of the vibrational theory of olfaction
journal, April 2015
- Block, Eric; Jang, Seogjoo; Matsunami, Hiroaki
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 21
Chemical Identity of a Rotting Animal-Like Odor Emitted from the Inflorescence of the Titan Arum ( Amorphophallus titanum )
journal, December 2010
- Shirasu, Mika; Fujioka, Kouki; Kakishima, Satoshi
- Bioscience, Biotechnology, and Biochemistry, Vol. 74, Issue 12
First insights into the mode of action of a “lachrymatory factor synthase” – Implications for the mechanism of lachrymator formation in Petiveria alliacea, Allium cepa and Nectaroscordum species
journal, November 2011
- He, Quan; Kubec, Roman; Jadhav, Abhijit P.
- Phytochemistry, Vol. 72, Issue 16
Fifty years of smelling sulfur: From the chemistry of garlic to the molecular basis for olfaction
journal, October 2016
- Block, Eric
- Phosphorus, Sulfur, and Silicon and the Related Elements, Vol. 192, Issue 2
An introduction to the scent of cacti
journal, May 1995
- Kaiser, Roman; Tollsten, Lars
- Flavour and Fragrance Journal, Vol. 10, Issue 3
Truffle thio-flavours reversibly inhibit truffle tyrosinase
journal, March 2003
- Zarivi, Osvaldo; Bonfigli, Antonella; Cesare, Patrizia
- FEMS Microbiology Letters, Vol. 220, Issue 1
3-Sulfanyl-4-methylpentan-1-ol in Dry-Hopped Beers: First Evidence of Glutathione S -Conjugates in Hop ( Humulus lupulus L.)
journal, November 2016
- Kankolongo Cibaka, Marie-Lucie; Decourrière, Laura; Lorenzo-Alonso, Celso-José
- Journal of Agricultural and Food Chemistry, Vol. 64, Issue 45
Combining In Vivo and In Vitro Approaches To Identify Human Odorant Receptors Responsive to Food Odorants
journal, January 2017
- Armelin-Correa, Lucia M.; Malnic, Bettina
- Journal of Agricultural and Food Chemistry, Vol. 66, Issue 10
Honeybees ( Apis mellifera ) learn to discriminate the smell of organic compounds from their respective deuterated isotopomers
journal, March 2014
- Gronenberg, Wulfila; Raikhelkar, Ajay; Abshire, Eric
- Proceedings of the Royal Society B: Biological Sciences, Vol. 281, Issue 1778