G Protein–Coupled Estrogen Receptor Agonist Improves Cerebral Microvascular Function After Hypoxia/Reoxygenation Injury in Male and Female Rats
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March 2013 |
Signaling, physiological functions and clinical relevance of the G protein-coupled estrogen receptor GPER
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September 2009 |
GPR30 estrogen receptor agonists induce mechanical hyperalgesia in the rat
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April 2008 |
Beneficial role of the GPR30 agonist G-1 in an animal model of multiple sclerosis
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September 2009 |
GPER Agonist G1 Attenuates Neuroinflammation and Dopaminergic Neurodegeneration in Parkinson Disease
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January 2017 |
Selective estrogen receptor modulators decrease the production of interleukin-6 and interferon-γ-inducible protein-10 by astrocytes exposed to inflammatory challenge in vitro
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January 2010 |
GPR30 Regulates Glutamate Transporter GLT-1 Expression in Rat Primary Astrocytes
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May 2012 |
GPR30 co-localizes with cholinergic neurons in the basal forebrain and enhances potassium-stimulated acetylcholine release in the hippocampus
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February 2011 |
Localisation of GPR30, a novel G protein-coupled oestrogen receptor, suggests multiple functions in rodent brain and peripheral tissues
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May 2009 |
Neurotrophic and neuroprotective actions of estrogen: Basic mechanisms and clinical implications
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May 2007 |
Heart Disease and Stroke Statistics—2011 Update: A Report From the American Heart Association
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February 2011 |
Estradiol-mediated ERK phosphorylation and apoptosis in vascular smooth muscle cells requires GPR 30
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November 2009 |
Estrogen Enhances Neurogenesis and Behavioral Recovery after Stroke
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July 2010 |
GPER1/GPR30 Activation Improves Neuronal Survival Following Global Cerebral Ischemia Induced by Cardiac Arrest in Mice
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September 2012 |
Sphingosine induces apoptosis in hippocampal neurons and astrocytes by activating caspase-3/-9 via a mitochondrial pathway linked to SDK/14-3-3 protein/Bax/cytochrome c
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June 2011 |
Estrogen Signaling through the Transmembrane G Protein–Coupled Receptor GPR30
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March 2008 |
Vasodilation in Response to the GPR30 Agonist G-1 is Not Different From Estradiol in the mRen2.Lewis Female Rat
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January 2011 |
The membrane-type estrogen receptor G-protein-coupled estrogen receptor suppresses lipopolysaccharide-induced interleukin 6 via inhibition of nuclear factor-kappa B pathway in murine macrophage cells
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July 2017 |
GPER expressed on microglia mediates the anti-inflammatory effect of estradiol in ischemic stroke
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March 2016 |
17β-Estradiol activates GPER- and ESR1-dependent pathways inducing apoptosis in GC-2 cells, a mouse spermatocyte-derived cell line
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May 2012 |
Estrogen destabilizes microtubules through an ion-conductivity-independent TRPV1 pathway: TRPV1-C-terminus regulates microtubule stability
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May 2011 |
Cloning of Human cDNA Encoding a Novel Heptahelix Receptor Expressed in Burkitt's Lymphoma and Widely Distributed in Brain and Peripheral Tissues
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November 1996 |
Identification of a Gene (GPR30) with Homology to the G-Protein-Coupled Receptor Superfamily Associated with Estrogen Receptor Expression in Breast Cancer
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November 1997 |
Timing of estrogen therapy after ovariectomy dictates the efficacy of its neuroprotective and antiinflammatory actions
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March 2007 |
G protein-coupled estrogen receptor 1-mediated effects in the rat myometrium
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November 2011 |
GPER: A new tool to protect dopaminergic neurons?
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October 2015 |
Estrogen receptors mediate rapid activation of phospholipase C pathway in the rat endometrium
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December 2011 |
The Role of Calcium in the Regulation of Apoptosis
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October 1997 |
Membrane Estrogen Receptor Regulates Experimental Autoimmune Encephalomyelitis through Up-regulation of Programmed Death 1
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February 2009 |
Stroke Increases G Protein-Coupled Estrogen Receptor Expression in the Brain of Male but Not Female Mice
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January 2013 |
Activation of G protein-coupled estrogen receptor 1 (GPER-1) ameliorates blood-brain barrier permeability after global cerebral ischemia in ovariectomized rats
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August 2016 |
NAD Induces Astrocyte Calcium Flux and Cell Death by ART2 and P2X7 Pathway
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September 2012 |
Estrogen Replacement Therapy for Stroke
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January 2014 |
Synthetic Estrogen Derivatives Demonstrate the Functionality of Intracellular GPR30
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July 2007 |
GPER activation is effective in protecting against inflammation-induced nigral dopaminergic loss and motor function impairment
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August 2017 |
Estrogens and Experimental Ischemic Stroke: A Systematic Review
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January 2006 |
Insights into Rapid Modulation of Neuroplasticity by Brain Estrogens
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August 2013 |
Distribution and characterization of estrogen receptor G protein-coupled receptor 30 in the rat central nervous system
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May 2007 |
Ameliorative effect of membrane-associated estrogen receptor G protein coupled receptor 30 activation on object recognition memory in mouse models of Alzheimer's disease
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July 2016 |
Estrogen neuroprotection and the critical period hypothesis
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January 2012 |
Oestrogen and Nigrostriatal Dopaminergic Neurodegeneration: Animal Models and Clinical Reports of Parkinson'S Disease
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July 2007 |
A novel method for culturing stellate astrocytes reveals spatially distinct Ca 2+ signaling and vesicle recycling in astrocytic processes
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December 2016 |
17β-Estradiol Inhibits Oxidative Stress-Induced Apoptosis in Keratinocytes by Promoting Bcl-2 Expression
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December 2003 |
G Protein-Coupled Estrogen Receptor-Selective Ligands Modulate Endometrial Tumor Growth
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January 2013 |
Anti-inflammatory effect of selective estrogen receptor modulators (SERMs) in microglial cells
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May 2005 |
In vivo effects of a GPR30 antagonist
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May 2009 |
Antidepressants, sertraline and paroxetine, increase calcium influx and induce mitochondrial damage-mediated apoptosis of astrocytes
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December 2017 |
Extra-nuclear estrogen receptor GPR30 regulates serotonin function in rat hypothalamus
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February 2009 |
A Transmembrane Intracellular Estrogen Receptor Mediates Rapid Cell Signaling
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March 2005 |
Estrogen biology: New insights into GPER function and clinical opportunities
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May 2014 |
Binding and activation of the seven-transmembrane estrogen receptor GPR30 by environmental estrogens: A potential novel mechanism of endocrine disruption
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December 2006 |
Estrogen and non-genomic upregulation of voltage-gated Na+ channel activity in MDA-MB-231 human breast cancer cells: Role in adhesion
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April 2010 |
Virtual and biomolecular screening converge on a selective agonist for GPR30
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March 2006 |
A novel putative G-protein-coupled receptor expressed in lung, heart and lymphoid tissue
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April 1997 |
Protein Kinase C δ Activates the MEK-ERK Pathway in a Manner Independent of Ras and Dependent on Raf
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September 1996 |
Acute Administration of Non-Classical Estrogen Receptor Agonists Attenuates Ischemia-Induced Hippocampal Neuron Loss in Middle-Aged Female Rats
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January 2010 |
GPR30 activation is neither necessary nor sufficient for acute neuroprotection by 17β-estradiol after an ischemic injury in organotypic hippocampal slice cultures
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May 2014 |
Expression and intracellular distribution of the G protein-coupled receptor 30 in rat hippocampal formation
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August 2008 |
The G-protein-coupled estrogen receptor GPER in health and disease
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August 2011 |
Astrocyte apoptosis: implications for neuroprotection
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February 2004 |
Apoptotic effect of ethanol is potentiated by caffeine-induced calcium release in rat astrocytes
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January 2006 |
Primary culture of cellular subtypes from postnatal mouse for in vitro studies of oxygen glucose deprivation
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August 2011 |
Impact of Astrocytes on the Injury Induced by In Vitro Ischemia
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March 2017 |
Estrogen Action Via the G Protein-Coupled Receptor, GPR30: Stimulation of Adenylyl Cyclase and cAMP-Mediated Attenuation of the Epidermal Growth Factor Receptor-to-MAPK Signaling Axis
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January 2002 |
Activation of the Novel Estrogen Receptor G Protein-Coupled Receptor 30 (GPR30) at the Plasma Membrane
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July 2007 |
Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines
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April 2010 |
Estrogen-Induced Activation of Erk-1 and Erk-2 Requires the G Protein-Coupled Receptor Homolog, GPR30, and Occurs via Trans-Activation of the Epidermal Growth Factor Receptor through Release of HB-EGF
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October 2000 |
Expression of estrogen receptor GPR30 in the rat spinal cord and in autonomic and sensory ganglia
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May 2009 |
JNK1 regulates histone acetylation in trigeminal neurons following chemical stimulation
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November 2008 |
Involvement of Na + -Ca 2+ Exchanger in Reperfusion-induced Delayed Cell Death of Cultured Rat Astrocytes
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May 1996 |
Neuroprotective effects of estrogens following ischemic stroke
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July 2009 |
17β-Estradiol Stimulates the Growth of Human Keratinocytes by Inducing Cyclin D2 Expression
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August 2004 |
Apoptosis in Ca 2 + reperfusion injury of cultured astrocytes: roles of reactive oxygen species and NF-κB activation : Astrocyte apoptosis by reactive oxygen species
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December 1999 |
Discovery of Three Novel G-Protein-Coupled Receptor Genes
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January 1998 |
Sex-Dependent Effects of G Protein–Coupled Estrogen Receptor Activity on Outcome After Ischemic Stroke
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March 2014 |
Cloning of cDNAs Encoding G Protein-Coupled Receptor Expressed in Human Endothelial Cells Exposed to Fluid Shear Stress
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November 1997 |
Reprint of ”GPR30 mediates estrogen rapid signaling and neuroprotection”
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May 2014 |
What Is the Role of Astrocyte Calcium in Neurophysiology?
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September 2008 |