Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation
Abstract
Time-resolved fluorescence anisotropy reveals conformational variation of single tau proteins in solution.
- Authors:
-
- Department of Chemistry, University of Wisconsin-Madison, 1101 University Ave, Madison, USA
- Department of Chemistry & Biochemistry, University of Denver, 2190 E. Iliff Ave., Denver, USA
- Publication Date:
- Sponsoring Org.:
- USDOE
- OSTI Identifier:
- 1490550
- Resource Type:
- Journal Article: Publisher's Accepted Manuscript
- Journal Name:
- Physical Chemistry Chemical Physics. PCCP
- Additional Journal Information:
- Journal Name: Physical Chemistry Chemical Physics. PCCP Journal Volume: 21 Journal Issue: 4; Journal ID: ISSN 1463-9076
- Publisher:
- Royal Society of Chemistry (RSC)
- Country of Publication:
- United Kingdom
- Language:
- English
Citation Formats
Foote, Alexander K., Manger, Lydia H., Holden, Michael R., Margittai, Martin, and Goldsmith, Randall H. Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation. United Kingdom: N. p., 2019.
Web. doi:10.1039/C8CP06971A.
Foote, Alexander K., Manger, Lydia H., Holden, Michael R., Margittai, Martin, & Goldsmith, Randall H. Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation. United Kingdom. https://doi.org/10.1039/C8CP06971A
Foote, Alexander K., Manger, Lydia H., Holden, Michael R., Margittai, Martin, and Goldsmith, Randall H. 2019.
"Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation". United Kingdom. https://doi.org/10.1039/C8CP06971A.
@article{osti_1490550,
title = {Time-resolved multirotational dynamics of single solution-phase tau proteins reveals details of conformational variation},
author = {Foote, Alexander K. and Manger, Lydia H. and Holden, Michael R. and Margittai, Martin and Goldsmith, Randall H.},
abstractNote = {Time-resolved fluorescence anisotropy reveals conformational variation of single tau proteins in solution.},
doi = {10.1039/C8CP06971A},
url = {https://www.osti.gov/biblio/1490550},
journal = {Physical Chemistry Chemical Physics. PCCP},
issn = {1463-9076},
number = 4,
volume = 21,
place = {United Kingdom},
year = {Wed Jan 23 00:00:00 EST 2019},
month = {Wed Jan 23 00:00:00 EST 2019}
}
Free Publicly Available Full Text
Publisher's Version of Record at https://doi.org/10.1039/C8CP06971A
Other availability
Cited by: 13 works
Citation information provided by
Web of Science
Web of Science
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
Soluble forms of tau are toxic in Alzheimer’s disease
journal, January 2012
- Kopeikina, Katherine; Hyman, Bradley; Spires-Jones, Tara
- Translational Neuroscience, Vol. 3, Issue 3
Abnormal Tau-Containing Filaments in Neurodegenerative Diseases
journal, June 2000
- Crowther, R. A.; Goedert, M.
- Journal of Structural Biology, Vol. 130, Issue 2-3
Asymmetric Modulation of Protein Order-Disorder Transitions by Phosphorylation and Partner Binding
journal, December 2015
- Banerjee, Priya R.; Mitrea, Diana M.; Kriwacki, Richard W.
- Angewandte Chemie International Edition, Vol. 55, Issue 5
Amyloid-β and tau — a toxic pas de deux in Alzheimer's disease
journal, December 2010
- Ittner, Lars M.; Götz, Jürgen
- Nature Reviews Neuroscience, Vol. 12, Issue 2
Single-molecule spectroscopy reveals photosynthetic LH2 complexes switch between emissive states
journal, June 2013
- Schlau-Cohen, G. S.; Wang, Q.; Southall, J.
- Proceedings of the National Academy of Sciences, Vol. 110, Issue 27
Characterizing the conformational ensemble of monomeric polyglutamine
journal, November 2005
- Wang, Xiaoling; Vitalis, Andreas; Wyczalkowski, Matthew A.
- Proteins: Structure, Function, and Bioinformatics, Vol. 63, Issue 2
Single-Molecule Studies of Intrinsically Disordered Proteins
journal, January 2014
- Brucale, Marco; Schuler, Benjamin; Samorì, Bruno
- Chemical Reviews, Vol. 114, Issue 6
Effects of surface tethering on protein folding mechanisms
journal, May 2006
- Friedel, M.; Baumketner, A.; Shea, J. -E.
- Proceedings of the National Academy of Sciences, Vol. 103, Issue 22
Identification of Single Molecules in Aqueous Solution by Time-Resolved Fluorescence Anisotropy
journal, January 1999
- Schaffer, J.; Volkmer, A.; Eggeling, C.
- The Journal of Physical Chemistry A, Vol. 103, Issue 3
On the wobbling-in-cone analysis of fluorescence anisotropy decay
journal, February 1982
- Kinosita, K.; Ikegami, A.; Kawato, S.
- Biophysical Journal, Vol. 37, Issue 2
Dissecting pigment architecture of individual photosynthetic antenna complexes in solution
journal, October 2015
- Wang, Quan; Moerner, W. E.
- Proceedings of the National Academy of Sciences, Vol. 112, Issue 45
Tau in physiology and pathology
journal, December 2015
- Wang, Yipeng; Mandelkow, Eckhard
- Nature Reviews Neuroscience, Vol. 17, Issue 1
Sensing cooperativity in ATP hydrolysis for single multisubunit enzymes in solution
journal, September 2011
- Jiang, Y.; Douglas, N. R.; Conley, N. R.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 41
Fluorescence correlation spectroscopy shows that monomeric polyglutamine molecules form collapsed structures in aqueous solutions
journal, October 2006
- Crick, S. L.; Jayaraman, M.; Frieden, C.
- Proceedings of the National Academy of Sciences, Vol. 103, Issue 45
Effect of librational motion on fluorescence depolarization and nuclear magnetic resonance relaxation in macromolecules and membranes
journal, June 1980
- Lipari, G.; Szabo, A.
- Biophysical Journal, Vol. 30, Issue 3
Principal-components analysis of shape fluctuations of single DNA molecules
journal, May 2007
- Cohen, A. E.; Moerner, W. E.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 31
An Experimental Comparison of the Maximum Likelihood Estimation and Nonlinear Least-Squares Fluorescence Lifetime Analysis of Single Molecules
journal, May 2001
- Maus, Michael; Cotlet, Mircea; Hofkens, Johan
- Analytical Chemistry, Vol. 73, Issue 9
Lifetime and Spectrally Resolved Characterization of the Photodynamics of Single Fluorophores in Solution Using the Anti-Brownian Electrokinetic Trap
journal, November 2012
- Wang, Quan; Moerner, W. E.
- The Journal of Physical Chemistry B, Vol. 117, Issue 16
Extreme disorder in an ultrahigh-affinity protein complex
journal, February 2018
- Borgia, Alessandro; Borgia, Madeleine B.; Bugge, Katrine
- Nature, Vol. 555, Issue 7694
Electron Spin Resonance of Nitrogen-Vacancy Defects Embedded in Single Nanodiamonds in an ABEL Trap
journal, August 2014
- Kayci, Metin; Chang, Huan-Cheng; Radenovic, Aleksandra
- Nano Letters, Vol. 14, Issue 9
Cryo-EM structures of tau filaments from Alzheimer’s disease
journal, July 2017
- Fitzpatrick, Anthony W. P.; Falcon, Benjamin; He, Shaoda
- Nature, Vol. 547, Issue 7662
Revealing Conformational Variants of Solution-Phase Intrinsically Disordered Tau Protein at the Single-Molecule Level
journal, November 2017
- Manger, Lydia H.; Foote, Alexander K.; Wood, Sharla L.
- Angewandte Chemie International Edition, Vol. 56, Issue 49
Identification of key amino acids responsible for the distinct aggregation properties of microtubule-associated protein 2 and tau
journal, August 2015
- Xie, Ce; Soeda, Yoshiyuki; Shinzaki, Yuki
- Journal of Neurochemistry, Vol. 135, Issue 1
Tau in Alzheimer's disease
journal, November 1998
- Mandelkow, E.
- Trends in Cell Biology, Vol. 8, Issue 11
Dynamics and folding of single two-stranded coiled-coil peptides studied by fluorescent energy transfer confocal microscopy
journal, November 2000
- Talaga, D. S.; Lau, W. L.; Roder, H.
- Proceedings of the National Academy of Sciences, Vol. 97, Issue 24
Electrokinetic trapping at the one nanometer limit
journal, May 2011
- Fields, A. P.; Cohen, A. E.
- Proceedings of the National Academy of Sciences, Vol. 108, Issue 22
The role of tau in neurodegeneration
journal, January 2009
- Gendron, Tania F.; Petrucelli, Leonard
- Molecular Neurodegeneration, Vol. 4, Issue 1
Time-resolved fluorescence anisotropy imaging applied to live cells
journal, January 2004
- Suhling, Klaus; Siegel, Jan; Lanigan, Peter M. P.
- Optics Letters, Vol. 29, Issue 6
Are Tangles as Toxic as They Look?
journal, June 2011
- Spires-Jones, Tara L.; Kopeikina, Katherine J.; Koffie, Robert M.
- Journal of Molecular Neuroscience, Vol. 45, Issue 3
Structural Polymorphism of 441-Residue Tau at Single Residue Resolution
journal, February 2009
- Mukrasch, Marco D.; Bibow, Stefan; Korukottu, Jegannath
- PLoS Biology, Vol. 7, Issue 2
Detection of Intensity Change Points in Time-Resolved Single-Molecule Measurements
journal, January 2005
- Watkins, Lucas P.; Yang, Haw
- The Journal of Physical Chemistry B, Vol. 109, Issue 1
Assembly of tau protein into Alzheimer paired helical filaments depends on a local sequence motif (306VQIVYK311) forming beta structure
journal, May 2000
- von Bergen, M.; Friedhoff, P.; Biernat, J.
- Proceedings of the National Academy of Sciences, Vol. 97, Issue 10
Charge interactions can dominate the dimensions of intrinsically disordered proteins
journal, July 2010
- Muller-Spath, S.; Soranno, A.; Hirschfeld, V.
- Proceedings of the National Academy of Sciences, Vol. 107, Issue 33
Confined dynamics of a ribosome-bound nascent globin: Cone angle analysis of fluorescence depolarization decays in the presence of two local motions
journal, October 2009
- Ellis, Jamie P.; Culviner, Peter H.; Cavagnero, Silvia
- Protein Science, Vol. 18, Issue 10
Domains of tau Protein and Interactions with Microtubules
journal, October 1994
- Gustke, N.; Trinczek, B.; Biernat, J.
- Biochemistry, Vol. 33, Issue 32
Identification of an Aggregation-Prone Structure of Tau
journal, October 2012
- Elbaum-Garfinkle, Shana; Rhoades, Elizabeth
- Journal of the American Chemical Society, Vol. 134, Issue 40
Single-molecule motions enable direct visualization of biomolecular interactions in solution
journal, March 2014
- Wang, Quan; Moerner, W. E.
- Nature Methods, Vol. 11, Issue 5
Resolving Mixtures in Solution by Single-Molecule Rotational Diffusivity
journal, July 2018
- Yang, Hsiang-Yu; Moerner, W. E.
- Nano Letters, Vol. 18, Issue 8
Direct single-molecule measurements of phycocyanobilin photophysics in monomeric C-phycocyanin
journal, August 2017
- Squires, Allison H.; Moerner, W. E.
- Proceedings of the National Academy of Sciences, Vol. 114, Issue 37
Watching conformational- and photodynamics of single fluorescent proteins in solution
journal, January 2010
- Goldsmith, Randall H.; Moerner, W. E.
- Nature Chemistry, Vol. 2, Issue 3
Single-Molecule Nanosecond Anisotropy Dynamics of Tethered Protein Motions
journal, January 2003
- Hu, Dehong; Lu, H. Peter
- The Journal of Physical Chemistry B, Vol. 107, Issue 2
Probing Single Biomolecules in Solution Using the Anti-Brownian Electrokinetic (ABEL) Trap
journal, March 2012
- Wang, Quan; Goldsmith, Randall H.; Jiang, Yan
- Accounts of Chemical Research, Vol. 45, Issue 11
An Adaptive Anti-Brownian Electrokinetic Trap with Real-Time Information on Single-Molecule Diffusivity and Mobility
journal, June 2011
- Wang, Quan; Moerner, W. E.
- ACS Nano, Vol. 5, Issue 7
Propagation of Tau Aggregates and Neurodegeneration
journal, July 2017
- Goedert, Michel; Eisenberg, David S.; Crowther, R. Anthony
- Annual Review of Neuroscience, Vol. 40, Issue 1
A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures
journal, February 2007
- Mukhopadhyay, S.; Krishnan, R.; Lemke, E. A.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 8