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Title: Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number

Abstract

An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R 0, is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a number of different treatment strategies on the basic reproduction number. All our results are valid for sufficiently small values of the control. However, in many cases it is possible to extend this analysis to larger values of the control as was illustrated by examples.

Authors:
ORCiD logo [1];  [2];  [3]
  1. Saint Petersburg State University, St. Petersburg (Russia)
  2. Universität Greifswald (Germany); Université Perpignan Via Domitia (France)
  3. Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Publication Date:
Research Org.:
Los Alamos National Lab. (LANL), Los Alamos, NM (United States)
Sponsoring Org.:
USDOE: Laboratory Directed Research and Development (LDRD)
OSTI Identifier:
1489969
Report Number(s):
LA-UR-18-31251
Journal ID: ISSN 0022-5193
Grant/Contract Number:  
89233218CNA000001
Resource Type:
Journal Article: Accepted Manuscript
Journal Name:
Journal of Theoretical Biology
Additional Journal Information:
Journal Volume: 462; Journal Issue: C; Journal ID: ISSN 0022-5193
Publisher:
Elsevier
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES; Biological Science

Citation Formats

Gromov, Dmitry, Bulla, Ingo, and Romero-Severson, Ethan O. Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number. United States: N. p., 2018. Web. doi:10.1016/j.jtbi.2018.11.029.
Gromov, Dmitry, Bulla, Ingo, & Romero-Severson, Ethan O. Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number. United States. doi:10.1016/j.jtbi.2018.11.029.
Gromov, Dmitry, Bulla, Ingo, and Romero-Severson, Ethan O. Tue . "Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number". United States. doi:10.1016/j.jtbi.2018.11.029.
@article{osti_1489969,
title = {Systematic evaluation of the population-level effects of alternative treatment strategies on the basic reproduction number},
author = {Gromov, Dmitry and Bulla, Ingo and Romero-Severson, Ethan O.},
abstractNote = {An approach to estimate the influence of the treatment-type controls on the basic reproduction number, R0, is proposed and elaborated. The presented approach allows one to estimate the effect of a given treatment strategy or to compare a number of different treatment strategies on the basic reproduction number. All our results are valid for sufficiently small values of the control. However, in many cases it is possible to extend this analysis to larger values of the control as was illustrated by examples.},
doi = {10.1016/j.jtbi.2018.11.029},
journal = {Journal of Theoretical Biology},
issn = {0022-5193},
number = C,
volume = 462,
place = {United States},
year = {2018},
month = {11}
}

Journal Article:
Free Publicly Available Full Text
This content will become publicly available on November 27, 2019
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