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Title: Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy

Authors:
; ;  [1];  [1]; ;  [2];  [3];  [1];  [4];  [4];  [4];  [5]; ;  [3];  [1]; ORCiD logo
  1. Department of Biochemistry and Molecular Biology, Indiana University School of Medicine, Indianapolis, Indiana 46202, United States
  2. Department of Materials Science Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States
  3. Division of Hematology Oncology, Department of Internal Medicine, University of Michigan, Ann Arbor, Michigan 48109, United States
  4. Department of Pharmaceutical Sciences, College of Pharmacy, University of Michigan, Ann Arbor, Michigan 48109, United States
  5. Department of Materials Science Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States; Macromolecular Science and Engineering, University of Michigan, Ann Arbor, Michigan 48109, United States
Publication Date:
Research Org.:
Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)
Sponsoring Org.:
UNIVERSITYOTHER
OSTI Identifier:
1484792
Resource Type:
Journal Article
Resource Relation:
Journal Name: Journal of Medicinal Chemistry; Journal Volume: 61; Journal Issue: 19
Country of Publication:
United States
Language:
ENGLISH

Citation Formats

Huddle, Brandt C., Grimley, Edward, Buchman, Cameron D., Chtcherbinine, Mikhail, Debnath, Bikash, Mehta, Pooja, Yang, Kun, Morgan, Cynthia A., Li, Siwei, Felton, Jeremy, Sun, Duxin, Mehta, Geeta, Neamati, Nouri, Buckanovich, Ronald J., Hurley, Thomas D., and Larsen, Scott D.. Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy. United States: N. p., 2018. Web. doi:10.1021/acs.jmedchem.8b00930.
Huddle, Brandt C., Grimley, Edward, Buchman, Cameron D., Chtcherbinine, Mikhail, Debnath, Bikash, Mehta, Pooja, Yang, Kun, Morgan, Cynthia A., Li, Siwei, Felton, Jeremy, Sun, Duxin, Mehta, Geeta, Neamati, Nouri, Buckanovich, Ronald J., Hurley, Thomas D., & Larsen, Scott D.. Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy. United States. doi:10.1021/acs.jmedchem.8b00930.
Huddle, Brandt C., Grimley, Edward, Buchman, Cameron D., Chtcherbinine, Mikhail, Debnath, Bikash, Mehta, Pooja, Yang, Kun, Morgan, Cynthia A., Li, Siwei, Felton, Jeremy, Sun, Duxin, Mehta, Geeta, Neamati, Nouri, Buckanovich, Ronald J., Hurley, Thomas D., and Larsen, Scott D.. Wed . "Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy". United States. doi:10.1021/acs.jmedchem.8b00930.
@article{osti_1484792,
title = {Structure-Based Optimization of a Novel Class of Aldehyde Dehydrogenase 1A (ALDH1A) Subfamily-Selective Inhibitors as Potential Adjuncts to Ovarian Cancer Chemotherapy},
author = {Huddle, Brandt C. and Grimley, Edward and Buchman, Cameron D. and Chtcherbinine, Mikhail and Debnath, Bikash and Mehta, Pooja and Yang, Kun and Morgan, Cynthia A. and Li, Siwei and Felton, Jeremy and Sun, Duxin and Mehta, Geeta and Neamati, Nouri and Buckanovich, Ronald J. and Hurley, Thomas D. and Larsen, Scott D.},
abstractNote = {},
doi = {10.1021/acs.jmedchem.8b00930},
journal = {Journal of Medicinal Chemistry},
number = 19,
volume = 61,
place = {United States},
year = {Wed May 16 00:00:00 EDT 2018},
month = {Wed May 16 00:00:00 EDT 2018}
}