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The principle of gating charge movement in a voltage-dependent K+ channel
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Free-energy relationships in ion channels activated by voltage and ligand
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Voltage-dependent Gating Rearrangements in the Intracellular T1–T1 Interface of a K + Channel
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Gating charge displacement in voltage-gated ion channels involves limited transmembrane movement
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Sensing charges of the Ciona intestinalis voltage-sensing phosphatase
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Effects of hydrostatic pressure on membrane processes. Sodium channels, calcium channels, and exocytosis
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Mechanism of Voltage Gating in Potassium Channels
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Water proton transfer and hydrogen bonding in ion channel gating
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Ion Channel Voltage Sensors: Structure, Function, and Pathophysiology
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PIP 2 Is a Necessary Cofactor for Ion Channel Function: How and Why?
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Temperature dependence of proton permeation through a voltage-gated proton channel
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Structural mechanism of voltage-dependent gating in an isolated voltage-sensing domain
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February 2014 |
Caution Is Required in Interpretation of Mutations in the Voltage Sensing Domain of Voltage Gated Channels as Evidence for Gating Mechanisms
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Probing α -3 10 Transitions in a Voltage-Sensing S4 Helix
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Modifications of sodium channel gating in Myxicola giant axons by deuterium oxide, temperature, and internal cations
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Small vertical movement of a K+ channel voltage sensor measured with luminescence energy transfer
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Expanding the view of proton pumping in cytochrome c oxidase through computer simulation
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Interaction of Diverse Voltage Sensor Homologs with Lipid Bilayers Revealed by Self-Assembly Simulations
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Estimating the voltage-dependent free energy change of ion channels using the median voltage for activation
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Hydrogen-Bonded Water Molecules in the M2 Channel of the Influenza A Virus Guide the Binding Preferences of Ammonium-Based Inhibitors
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Thermodynamics of electromechanical coupling in voltage-gated ion channels
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Solvent substitution as a probe of channel gating in Myxicola. Effects of D2O on kinetic properties of drugs that occlude channels
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Voltage-Gated Proton Channels: Molecular Biology, Physiology, and Pathophysiology of the H V Family
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Histidine Scanning Mutagenesis of Basic Residues of the S4 Segment of the Shaker K + Channel
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The components of membrane conductance in the giant axon of Loligo
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Movement and Crevices Around a Sodium Channel S3 Segment
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Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo
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Reduced voltage sensitivity in a K+-channel voltage sensor by electric field remodeling
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The dual effect of membrane potential on sodium conductance in the giant axon of Loligo
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Charge Movement Associated with the Opening and Closing of the Activation Gates of the Na Channels
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Voltage Sensor of Kv1.2: Structural Basis of Electromechanical Coupling
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Influence of the Selectivity Filter Properties on Proton Selectivity in the Influenza A M2 Channel
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Voltage-dependent gating and gating charge measurements in the Kv1.2 potassium channel
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Focused Electric Field across the Voltage Sensor of Potassium Channels
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Quantum calculations on salt bridges with water: Potentials, structure, and properties
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Functional analysis of an archaebacterial voltage-dependent K+ channel
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Kv Channel Gating Requires a Compatible S4-S5 Linker and Bottom Part of S6, Constrained by Non-interacting Residues
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The gating charge should not be estimated by fitting a two-state model to a Q-V curve
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LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b
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Phospholipids and the origin of cationic gating charges in voltage sensors
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Detecting Rearrangements of Shaker and NaChBac in Real-Time with Fluorescence Spectroscopy in Patch-Clamped Mammalian Cells
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Proton Transfer in the K-Channel Analog of B-Type Cytochrome c Oxidase from Thermus thermophilus
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Pi5 and Pi6, two undescribed peptides from the venom of the scorpion Pandinus imperator and their effects on K + -channels
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Quantum mechanical calculations of charge effects on gating the KcsA channel
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How to open a proton pore—more than S4?
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Temperature and Voltage Coupling to Channel Opening in Transient Receptor Potential Melastatin 8 (TRPM8)
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A proton pore in a potassium channel voltage sensor reveals a focused electric field
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A Resonance Model Gives the Response to Membrane Potential for an Ion Channel
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Intermolecular Proton Transfer between Two Methylamine Molecules with an External Electric Field in the Gas Phase
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The isolated voltage sensing domain of the Shaker potassium channel forms a voltage-gated cation channel
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Heme impairs the ball-and-chain inactivation of potassium channels
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Crystal Structure of a Mammalian Voltage-Dependent Shaker Family K+ Channel
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Intermediate states of the Kv1.2 voltage sensor from atomistic molecular dynamics simulations
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Representation of Ion–Protein Interactions Using the Drude Polarizable Force-Field
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Simulating the Activation of Voltage Sensing Domain for a Voltage-Gated Sodium Channel Using Polarizable Force Field
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K+/Na+ Selectivity in K Channels and Valinomycin: Over-coordination Versus Cavity-size constraints
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A proton pathway with large proton polarizability and the proton pumping mechanism in bacteriorhodopsin — Fourier transform difference spectra of photoproducts of bacteriorhodopsin and of its pentademethyl analogue
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Ionic channels in biological membranes- electrostatic analysis of a natural nanotube
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Voltage-dependent motion of the catalytic region of voltage-sensing phosphatase monitored by a fluorescent amino acid
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In Vivo Measurement of Intramolecular Distances Using Genetically Encoded Reporters
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ONIOM: A Multilayered Integrated MO + MM Method for Geometry Optimizations and Single Point Energy Predictions. A Test for Diels−Alder Reactions and Pt(P( t -Bu) 3 ) 2 + H 2 Oxidative Addition
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Functional diversity of potassium channel voltage-sensing domains
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February 2017 |
Proton Release from the Histidine-Tetrad in the M2 Channel of the Influenza A Virus
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October 2014 |
Gating modifier toxins reveal a conserved structural motif in voltage-gated Ca2+ and K+ channels
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A voltage-gated proton-selective channel lacking the pore domain
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Coulomb blockade model of permeation and selectivity in biological ion channels
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The Voltage-Gated Proton Channel: A Riddle, Wrapped in a Mystery, inside an Enigma
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May 2015 |
Calibrated Measurement of Gating-Charge Arginine Displacement in the KvAP Voltage-Dependent K+ Channel
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November 2005 |
The potassium permeability of a giant nerve fibre
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April 1955 |
Voltage-dependent K+ channel gating and voltage sensor toxin sensitivity depend on the mechanical state of the lipid membrane
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Voltage gating and anions, especially phosphate: A model system
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November 2005 |
The pore of voltage-gated potassium ion channels is strained when closed
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May 2013 |
An engineered scorpion toxin analogue with improved Kv1.3 selectivity displays reduced conformational flexibility
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Deuterium Isotope Effects on Permeation and Gating of Proton Channels in Rat Alveolar Epithelium
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Quantum Effects in a Simple Ring with Hydrogen Bonds
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The Structure of the Potassium Channel: Molecular Basis of K+ Conduction and Selectivity
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A specialized molecular motion opens the Hv1 voltage-gated proton channel
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S4-based voltage sensors have three major conformations
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Kcsa: It's a Potassium Channel
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Biodiversity of voltage sensor domain proteins
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Consequences of phosphate-arginine complexes in voltage gated ion channels
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Structural basis for ion permeation mechanism in pentameric ligand-gated ion channels
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Principles underlying energetic coupling along an allosteric communication trajectory of a voltage-activated K+ channel
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Structure of the full-length Shaker potassium channel Kv1.2 by normal-mode-based X-ray crystallographic refinement
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Voltage Gated Ion Channel Function: Gating, Conduction, and the Role of Water and Protons
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Unraveling the mechanism of proton translocation in the extracellular half-channel of bacteriorhodopsin: Proton Translocation in Bacteriorhodopsin
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Using hierarchical thermodynamic linkage analysis to study ion channel gating
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New Structural Perspectives on K+ Channel Gating
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Principles of conduction and hydrophobic gating in K+ channels
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Acetylcholine receptor channel structure probed in cysteine-substitution mutants
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A Fluorometric Approach to Local Electric Field Measurements in a Voltage-Gated Ion Channel
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A Voltage Sensor-Domain Protein Is a Voltage-Gated Proton Channel
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Histidines, heart of the hydrogen ion channel from influenza A virus: Toward an understanding of conductance and proton selectivity
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A model for ion channel voltage gating with static S4 segments
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SYMPOSIUM REVIEW: Phosphoinositides: lipid regulators of membrane proteins: Phosphoinositides instruct membrane proteins
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Molecular Dynamics Simulations of Voltage-Gated Cation Channels: Insights on Voltage-Sensor Domain Function and Modulation
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Dissecting the Disulphide-coupled Folding Pathway of Bovine Pancreatic Trypsin Inhibitor
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Fast gating in the Shaker K+ channel and the energy landscape of activation
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Voltage Sensor Movements
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Kinetics of PIP 2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells
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Atomic scale movement of the voltage-sensing region in a potassium channel measured via spectroscopy
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Kinetic gating of the proton pump in cytochrome c oxidase
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A possible role for phosphate in complexing the arginines of S4 in voltage gated channels
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Direct Evidence of Conformational Changes Associated with Voltage Gating in a Voltage Sensor Protein by Time-Resolved X-ray/Neutron Interferometry
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Site Directed Spin Labeling and EPR Spectroscopic Studies of Pentameric Ligand-Gated Ion Channels
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Binding Modes of μ-Conotoxin to the Bacterial Sodium Channel (NaVAb)
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Tethering Naturally Occurring Peptide Toxins for Cell-Autonomous Modulation of Ion Channels and Receptors In Vivo
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Margatoxin is a non-selective inhibitor of human Kv1.3 K+ channels
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Mn(II) deposition on anodes and its effects on capacity fade in spinel lithium manganate–carbon systems
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Interactions between lipids and voltage sensor paddles detected with tarantula toxins
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Molecular determinants of Hv1 proton channel inhibition by guanidine derivatives
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The Signature Sequence of Voltage-gated Potassium Channels Projects into the External Vestibule
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Double Mutant Cycle Analysis Identified a Critical Leucine Residue in the IIS4S5 Linker for the Activation of the CaV2.3 Calcium Channel
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Kinetics of PIP 2 metabolism and KCNQ2/3 channel regulation studied with a voltage-sensitive phosphatase in living cells
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A Marine Snail Neurotoxin Shares with Scorpion Toxins a Convergent Mechanism of Blockade on the Pore of Voltage-Gated K Channels
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Helical Structure of the Cooh Terminus of S3 and Its Contribution to the Gating Modifier Toxin Receptor in Voltage-Gated Ion Channels
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Effects of Kv1.2 Intracellular Regions on Activation of Kv2.1 Channels
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The Fast Component of hERG Gating Charge: An Interaction between D411 in the S1 and S4 Residues
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Structure, Molecular Modeling, and Function of the Novel Potassium Channel Blocker Urotoxin Isolated from the Venom of the Australian Scorpion Urodacus yaschenkoi
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Cooperative Interactions Between R531 and Acidic Residues in the Voltage Sensing Module of hERG1 Channels
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Interactions Between Charged Residues in the Transmembrane Segments of the Voltage-sensing Domain in the hERG Channel
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Isolation, chemical and functional characterization of several new K+-channel blocking peptides from the venom of the scorpion Centruroides tecomanus
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Hydrophobic plug functions as a gate in voltage-gated proton channels
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Coulomb blockade model of permeation and selectivity in biological ion channels
- Kaufman, Igor Kh.; McClintock, Peter V. E.; Eisenberg, Robert S.
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Institute of Physics (IOP),Deutsche Physikalische Gesellschaft (DPG)
https://doi.org/10.5446/38744
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Numerical methods for a Poisson-Nernst-Planck-Fermi model of biological ion channels
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Sodium channel activation mechanisms. Insights from deuterium oxide substitution
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Solute inaccessible aqueous volume changes during opening of the potassium channel of the squid giant axon
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Voltage-sensitive and solvent-sensitive processes in ion channel gating. Kinetic effects of hyperosmolar media on activation and deactivation of sodium channels
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Alpha-helical hydrophobic polypeptides form proton-selective channels in lipid bilayers
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Crystallographic Structures of the M and N Intermediates of Bacteriorhodopsin: Assembly of a Hydrogen-bonded Chain of Water Molecules Between Asp-96 and the Retinal Schiff Base
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The Polar T1 Interface Is Linked to Conformational Changes that Open the Voltage-Gated Potassium Channel
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Ion channel gating and proton transport
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Molecular Basis of Charge Movement in Voltage-Gated Sodium Channels
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Factors controlling the selectivity for Na + over Mg 2+ in sodium transporters and enzymes
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Regulatory role of the extreme C-terminal end of the S6 inner helix in C-terminal-truncated Kv1.2 channel activation
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On ionic conduction in potassium channels
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A Limited 4 Å Radial Displacement of the S4-S5 Linker Is Sufficient for Internal Gate Closing in Kv Channels
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Statistical Theory of Selectivity and Conductivity in Biological Channels
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Ionic channels in biological membranes. Electrostatic analysis of a natural nanotube
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text
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January 2016 |