Structure of the core domain of human cardiac troponin in the Ca2+-saturated form
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July 2003 |
Ca-dependence of isometric force kinetics in single skinned ventricular cardiomyocytes from rats
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September 1996 |
Role of Ca2+ in determining the rate of tension development and relaxation in rat skinned myocardium
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March 2004 |
Isometric force redevelopment of skinned muscle fibers from rabbit activated with and without Ca2+
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November 1994 |
Calmidazolium alters Ca2+ regulation of tension redevelopment rate in skinned skeletal muscle
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November 1996 |
Effect of Ca2+ on cross-bridge turnover kinetics in skinned single rabbit psoas fibers: implications for regulation of muscle contraction.
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May 1988 |
Modulation of the rate of cardiac muscle contraction by troponin C constructs with various calcium binding affinities
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October 2007 |
Rate of Tension Development in Cardiac Muscle Varies With Level of Activator Calcium
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January 1995 |
Roles of Ca 2+ and Crossbridge Kinetics in Determining the Maximum Rates of Ca 2+ Activation and Relaxation in Rat and Guinea Pig Skinned Trabeculae
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July 1998 |
The Filament Lattice of Striated Muscle
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April 1998 |
Thick-to-Thin Filament Surface Distance Modulates Cross-Bridge Kinetics in Drosophila Flight Muscle
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September 2012 |
Axial and Radial Forces of Cross-Bridges Depend on Lattice Spacing
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December 2010 |
An X-Ray Diffraction Study on Mouse Cardiac Cross-Bridge Function In Vivo: Effects of Adrenergic β-Stimulation
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March 2006 |
Nano-imaging of the beating mouse heart in vivo: Importance of sarcomere dynamics, as opposed to sarcomere length per se, in the regulation of cardiac function
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December 2015 |
In Vivo Analysis of Troponin C Knock-In (A8V) Mice: Evidence that TNNC1 Is a Hypertrophic Cardiomyopathy Susceptibility Gene
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October 2015 |
Myosin Rod Hypophosphorylation and CB Kinetics in Papillary Muscles from a TnC-A8V KI Mouse Model
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April 2017 |
Pathogenesis of depression‐ and anxiety‐like behavior in an animal model of hypertrophic cardiomyopathy
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February 2017 |
Expanding the range of free calcium regulation in biological solutions
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December 2005 |
Effects of pH on contraction of rabbit fast and slow skeletal muscle fibers
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June 1988 |
Regulation of Skeletal Muscle Tension Redevelopment by Troponin C Constructs with Different Ca2+ Affinities
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May 1999 |
Effects of inorganic phosphate analogues on stiffness and unloaded shortening of skinned muscle fibres from rabbit.
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January 1993 |
Hypertrophic Cardiomyopathy Cardiac Troponin C Mutations Differentially Affect Slow Skeletal and Cardiac Muscle Regulation
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April 2017 |
The BioCAT undulator beamline 18ID: a facility for biological non-crystalline diffraction and X-ray absorption spectroscopy at the Advanced Photon Source
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August 2004 |
Impact of osmotic compression on sarcomere structure and myofilament calcium sensitivity of isolated rat myocardium
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October 2006 |
Changes in thick filament structure during compression of the filament lattice in relaxed frog sartorius muscle
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October 1989 |
Slowed Dynamics of Thin Filament Regulatory Units Reduces Ca2+-Sensitivity of Cardiac Biomechanical Function
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January 2013 |
Calcium Regulation of Tension Redevelopment Kinetics with 2-Deoxy-ATP or Low [ATP] in Rabbit Skeletal Muscle
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April 1998 |
Strong Cross-bridges Potentiate the Ca2+ Affinity Changes Produced by Hypertrophic Cardiomyopathy Cardiac Troponin C Mutants in Myofilaments
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January 2011 |
Myofilament lattice spacing as a function of sarcomere length in isolated rat myocardium
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November 2000 |
Response of Equatorial X-Ray Reflections and Stiffness to Altered Sarcomere Length and Myofilament Lattice Spacing in Relaxed Skinned Cardiac Muscle
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February 2004 |
Bepridil opens the regulatory N-terminal lobe of cardiac troponin C
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May 2000 |
Structure of the Regulatory N-domain of Human Cardiac Troponin C in Complex with Human Cardiac Troponin I147–163 and Bepridil
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August 2002 |
Cardiac Length Dependence of Force and Force Redevelopment Kinetics with Altered Cross-Bridge Cycling
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September 2004 |
Rate of force generation in muscle: correlation with actomyosin ATPase activity in solution.
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May 1986 |
A Simple Model with Myofilament Compliance Predicts Activation-Dependent Crossbridge Kinetics in Skinned Skeletal Fibers
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December 2002 |
Compliant Realignment of Binding Sites in Muscle: Transient Behavior and Mechanical Tuning
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April 1998 |
A Spatially Explicit Nanomechanical Model of the Half-Sarcomere: Myofilament Compliance Affects Ca 2+ -Activation
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November 2004 |
Stiffness and force in activated frog skeletal muscle fibers
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February 1986 |
Sarcomere-length dependence of lattice volume and radial mass transfer of myosin cross-bridges in rat papillary muscle
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May 2004 |
Molecular and functional characterization of novel hypertrophic cardiomyopathy susceptibility mutations in TNNC1-encoded troponin C
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August 2008 |
Enhanced troponin I binding explains the functional changes produced by the hypertrophic cardiomyopathy mutation A8V of cardiac troponin C
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July 2016 |
A Functional and Structural Study of Troponin C Mutations Related to Hypertrophic Cardiomyopathy
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July 2009 |
Myofilament calcium sensitivity does not affect cross-bridge activation-relaxation kinetics
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March 2007 |
Role of Ca2+ and Cross-Bridges in Skeletal Muscle Thin Filament Activation Probed with Ca2+ Sensitizers
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April 1999 |
Tension generation and relaxation in single myofibrils from human atrial and ventricular myocardium
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November 2006 |
A proton nuclear magnetic resonance and molecular modeling study of calmidazolium (R24571) binding to calmodulin and skeletal muscle troponin C.
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June 1990 |
Familial hypertrophic cardiomyopathy mutations in troponin I (K183Δ, G203S, K206Q) enhance filament sliding
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July 2003 |
Micromechanical Thermal Assays of Ca 2+ -Regulated Thin-Filament Function and Modulation by Hypertrophic Cardiomyopathy Mutants of Human Cardiac Troponin
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January 2012 |
Expression of cardiac troponin T with COOH-terminal truncation accelerates cross-bridge interaction kinetics in mouse myocardium
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October 2004 |
The troponin complex and regulation of muscle contraction
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June 1995 |
Calcium binding kinetics of troponin C strongly modulate cooperative activation and tension kinetics in cardiac muscle
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January 2011 |
Clusters of isoleucine, leucine, and valine side chains define cores of stability in high-energy states of globular proteins: Sequence determinants of structure and stability: BASiC Clusters-Stability Cores of Proteins
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December 2015 |
NMR solution structure of calcium-saturated skeletal muscle troponin C
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December 1995 |
Structure of Cardiac Muscle Troponin C Unexpectedly Reveals a Closed Regulatory Domain
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July 1997 |
Fluorescent Protein-Based Ca2+ Sensor Reveals Global, Divalent Cation-Dependent Conformational Changes in Cardiac Troponin C
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October 2016 |
Allosteric Transmission along a Loosely Structured Backbone Allows a Cardiac Troponin C Mutant to Function with Only One Ca2+ Ion
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February 2017 |
Amide hydrogens reveal a temperature-dependent structural transition that enhances site-II Ca2+-binding affinity in a C-domain mutant of cardiac troponin C
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April 2017 |
Filament Compliance Influences Cooperative Activation of Thin Filaments and the Dynamics of Force Production in Skeletal Muscle
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May 2012 |
Sarcomere length dependence of the rate of tension redevelopment and submaximal tension in rat and rabbit skinned skeletal muscle fibres
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June 1997 |
Myosin filament activation in the heart is tuned to the mechanical task
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March 2017 |
Myosin light chain phosphorylation enhances contraction of heart muscle via structural changes in both thick and thin filaments
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May 2016 |
In Situ Measurements of Crossbridge Dynamics and Lattice Spacing in Rat Hearts by X-Ray Diffraction: Sensitivity to Regional Ischemia
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June 2004 |
Lattice spacing changes accompanying isometric tension development in intact single muscle fibers
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November 1994 |
Time-resolved changes in equatorial x-ray diffraction and stiffness during rise of tetanic tension in intact length-clamped single muscle fibers
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June 1991 |
Characterization of radial force and radial stiffness in Ca(2+)-activated skinned fibres of the rabbit psoas muscle.
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September 1991 |
Polymer crowders and protein crowders act similarly on protein folding stability
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January 2013 |
The Force Exerted by a Muscle Cross-Bridge Depends Directly on the Strength of the Actomyosin Bond
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October 2004 |
Viscosity and solute dependence of F-actin translocation by rabbit skeletal heavy meromyosin
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June 2000 |
X-ray Diffraction Studies of the Thick Filament in Permeabilized Myocardium from Rabbit
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November 2006 |
Donnan potentials in rabbit psoas muscle in rigor
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July 1985 |
Radial equilibrium lengths of actomyosin cross-bridges in muscle
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November 1996 |
Detection of radial crossbridge force by lattice spacing changes in intact single muscle fibers
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December 1990 |
Cardiac excitation–contraction coupling
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January 2002 |
Mutations in Troponin that cause HCM, DCM AND RCM: What can we learn about thin filament function?
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May 2010 |
Thin Filament Mutations: Developing an Integrative Approach to a Complex Disorder
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March 2011 |
Sarcomeric proteins and inherited cardiomyopathies
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December 2007 |
Genetic profile of hypertrophic cardiomyopathy in Tunisia: Is it different?
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January 2015 |
Computational simulation of hypertrophic cardiomyopathy mutations in Troponin I: Influence of increased myofilament calcium sensitivity on isometric force, ATPase and [Ca2+]i
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January 2007 |
Cardiac muscle mechanics: Sarcomere length matters
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February 2016 |
Interfilament Spacing Is Preserved during Sarcomere Length Isometric Contractions in Rat Cardiac Trabeculae
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May 2007 |
Cross-bridge kinetics in rat myocardium: effect of sarcomere length and calcium activation
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August 2000 |
The Need for Speed: Mice, Men, and Myocardial Kinetic Reserve
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July 2016 |
The familial hypertrophic cardiomyopathy-associated myosin mutation R403Q accelerates tension generation and relaxation of human cardiac myofibrils: Human cardiac myofibril mechanics and R403Q myosin
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July 2008 |
Faster cross-bridge detachment and increased tension cost in human hypertrophic cardiomyopathy with the R403Q MYH7 mutation: Increased tension cost in human HCM with the MYH7 R403Q mutation
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July 2014 |