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Title: Near-field infrared nanospectroscopy and super-resolution fluorescence microscopy enable complementary nanoscale analyses of lymphocyte nuclei

Abstract

First near-field infrared spectroscopy and imaging of lymphocyte nucleus at 30 nm spatial resolution reveals spectrochemically distinct regions in nuclear organization.

Authors:
ORCiD logo [1];  [2];  [3];  [4];  [5]; ORCiD logo [6]; ORCiD logo [1]
  1. Chemistry, University of Manitoba, Winnipeg, Canada, Biomedical Engineering Program
  2. Neaspec GmbH, 82512 Martinsried, Germany
  3. Physiology and Pathophysiology, University of Manitoba, Winnipeg, Canada, Department of Biomedical Sciences
  4. Genomic Centre for Cancer Research and Diagnosis, Winnipeg, Canada, Cell Biology, Research Institute of Oncology and Hematology
  5. Physiology and Pathophysiology, University of Manitoba, Winnipeg, Canada
  6. Physiology and Pathophysiology, University of Manitoba, Winnipeg, Canada, Genomic Centre for Cancer Research and Diagnosis
Publication Date:
Sponsoring Org.:
USDOE
OSTI Identifier:
1477893
Grant/Contract Number:  
AC02-05CH11231
Resource Type:
Journal Article: Publisher's Accepted Manuscript
Journal Name:
The Analyst
Additional Journal Information:
Journal Name: The Analyst Journal Volume: 143 Journal Issue: 24; Journal ID: ISSN 0003-2654
Publisher:
Royal Society of Chemistry (RSC)
Country of Publication:
United Kingdom
Language:
English

Citation Formats

Ajaezi, Godwin C., Eisele, Max, Contu, Fabio, Lal, Sadhana, Rangel-Pozzo, Aline, Mai, Sabine, and Gough, Kathleen M. Near-field infrared nanospectroscopy and super-resolution fluorescence microscopy enable complementary nanoscale analyses of lymphocyte nuclei. United Kingdom: N. p., 2018. Web. doi:10.1039/C8AN01341A.
Ajaezi, Godwin C., Eisele, Max, Contu, Fabio, Lal, Sadhana, Rangel-Pozzo, Aline, Mai, Sabine, & Gough, Kathleen M. Near-field infrared nanospectroscopy and super-resolution fluorescence microscopy enable complementary nanoscale analyses of lymphocyte nuclei. United Kingdom. doi:10.1039/C8AN01341A.
Ajaezi, Godwin C., Eisele, Max, Contu, Fabio, Lal, Sadhana, Rangel-Pozzo, Aline, Mai, Sabine, and Gough, Kathleen M. Mon . "Near-field infrared nanospectroscopy and super-resolution fluorescence microscopy enable complementary nanoscale analyses of lymphocyte nuclei". United Kingdom. doi:10.1039/C8AN01341A.
@article{osti_1477893,
title = {Near-field infrared nanospectroscopy and super-resolution fluorescence microscopy enable complementary nanoscale analyses of lymphocyte nuclei},
author = {Ajaezi, Godwin C. and Eisele, Max and Contu, Fabio and Lal, Sadhana and Rangel-Pozzo, Aline and Mai, Sabine and Gough, Kathleen M.},
abstractNote = {First near-field infrared spectroscopy and imaging of lymphocyte nucleus at 30 nm spatial resolution reveals spectrochemically distinct regions in nuclear organization.},
doi = {10.1039/C8AN01341A},
journal = {The Analyst},
number = 24,
volume = 143,
place = {United Kingdom},
year = {Mon Dec 03 00:00:00 EST 2018},
month = {Mon Dec 03 00:00:00 EST 2018}
}

Journal Article:
Free Publicly Available Full Text
This content will become publicly available on October 11, 2019
Publisher's Accepted Manuscript

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