skip to main content
OSTI.GOV title logo U.S. Department of Energy
Office of Scientific and Technical Information

Title: Cellulose solvent-based pretreatment for enhanced second-generation biofuel production: a review


Cellulose solvent-based fractionation technologies can prove to be economical to enhance lignocellulosic biomass microbial conversion to fuels and chemicals.

ORCiD logo [1]; ORCiD logo [2]; ORCiD logo [3]
  1. Department of Chemical Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran
  2. Department of Chemical Engineering, Isfahan University of Technology, Isfahan 84156-83111, Iran, Industrial Biotechnology Group
  3. Center for Environmental Research and Technology (CE-CERT), Bourns College of Engineering, University of California Riverside (UCR), Riverside, USA
Publication Date:
Sponsoring Org.:
OSTI Identifier:
Resource Type:
Journal Article: Publisher's Accepted Manuscript
Journal Name:
Sustainable Energy & Fuels
Additional Journal Information:
Journal Name: Sustainable Energy & Fuels Journal Volume: 3 Journal Issue: 1; Journal ID: ISSN 2398-4902
Royal Society of Chemistry (RSC)
Country of Publication:
United Kingdom

Citation Formats

Satari, Behzad, Karimi, Keikhosro, and Kumar, Rajeev. Cellulose solvent-based pretreatment for enhanced second-generation biofuel production: a review. United Kingdom: N. p., 2019. Web. doi:10.1039/C8SE00287H.
Satari, Behzad, Karimi, Keikhosro, & Kumar, Rajeev. Cellulose solvent-based pretreatment for enhanced second-generation biofuel production: a review. United Kingdom. doi:10.1039/C8SE00287H.
Satari, Behzad, Karimi, Keikhosro, and Kumar, Rajeev. Tue . "Cellulose solvent-based pretreatment for enhanced second-generation biofuel production: a review". United Kingdom. doi:10.1039/C8SE00287H.
title = {Cellulose solvent-based pretreatment for enhanced second-generation biofuel production: a review},
author = {Satari, Behzad and Karimi, Keikhosro and Kumar, Rajeev},
abstractNote = {Cellulose solvent-based fractionation technologies can prove to be economical to enhance lignocellulosic biomass microbial conversion to fuels and chemicals.},
doi = {10.1039/C8SE00287H},
journal = {Sustainable Energy & Fuels},
number = 1,
volume = 3,
place = {United Kingdom},
year = {Tue Jan 01 00:00:00 EST 2019},
month = {Tue Jan 01 00:00:00 EST 2019}

Journal Article:
Free Publicly Available Full Text
This content will become publicly available on September 28, 2019
Publisher's Accepted Manuscript

Save / Share:

Works referenced in this record:

Enhancement of cellulose saccharification kinetics using an ionic liquid pretreatment step
journal, January 2006

  • Dadi, Anantharam P.; Varanasi, Sasidhar; Schall, Constance A.
  • Biotechnology and Bioengineering, Vol. 95, Issue 5, p. 904-910
  • DOI: 10.1002/bit.21047

Deconstruction of Lignocellulosic Biomass to Fuels and Chemicals
journal, July 2011

Visualization of biomass solubilization and cellulose regeneration during ionic liquid pretreatment of switchgrass
journal, September 2009

  • Singh, Seema; Simmons, Blake A.; Vogel, Kenneth P.
  • Biotechnology and Bioengineering, Vol. 104, Issue 1, p. 68-75
  • DOI: 10.1002/bit.22386

Recovery of microalgal biomass and metabolites: process options and economics
journal, January 2003

  • Molina Grima, E.; Belarbi, E.-H.; Aci�n Fern�ndez, F. G.
  • Biotechnology Advances, Vol. 20, Issue 7-8, p. 491-515
  • DOI: 10.1016/S0734-9750(02)00050-2

Acid Hydrolysis of Cellulose as the Entry Point into Biorefinery Schemes
journal, December 2009

High-Yield Hydrogen Production from Starch and Water by a Synthetic Enzymatic Pathway
journal, May 2007

  • Zhang, Y.-H. Percival; Evans, Barbara R.; Mielenz, Jonathan R.
  • PLoS ONE, Vol. 2, Issue 5, Article No. e456
  • DOI: 10.1371/journal.pone.0000456

Advancing oleaginous microorganisms to produce lipid via metabolic engineering technology
journal, October 2013

Ionic liquid pretreatment of cellulosic biomass: Enzymatic hydrolysis and ionic liquid recycle
journal, December 2010

  • Shill, Kierston; Padmanabhan, Sasisanker; Xin, Qin
  • Biotechnology and Bioengineering, Vol. 108, Issue 3, p. 511-520
  • DOI: 10.1002/bit.23014

Cellulases and biofuels
journal, June 2009

The impact of dilute sulfuric acid on the selectivity of xylooligomer depolymerization to monomers
journal, February 2008

Ionic liquid-mediated selective extraction of lignin from wood leading to enhanced enzymatic cellulose hydrolysis
journal, April 2009

  • Lee, Sang Hyun; Doherty, Thomas V.; Linhardt, Robert J.
  • Biotechnology and Bioengineering, Vol. 102, Issue 5, p. 1368-1376
  • DOI: 10.1002/bit.22179

Biomass Recalcitrance: Engineering Plants and Enzymes for Biofuels Production
journal, February 2007

  • Himmel, M. E.; Ding, S.-Y.; Johnson, D. K.
  • Science, Vol. 315, Issue 5813, p. 804-807
  • DOI: 10.1126/science.1137016

In vitro hydrogen production by glucose dehydrogenase and hydrogenase
journal, July 1996

  • Woodward, Jonathan; Mattingly, Susan M.; Danson, Michael
  • Nature Biotechnology, Vol. 14, Issue 7, p. 872-874
  • DOI: 10.1038/nbt0796-872

Integration of chemical catalysis with extractive fermentation to produce fuels
journal, November 2012

  • Anbarasan, Pazhamalai; Baer, Zachary C.; Sreekumar, Sanil
  • Nature, Vol. 491, Issue 7423, p. 235-239
  • DOI: 10.1038/nature11594

Effect of enzyme supplementation at moderate cellulase loadings on initial glucose and xylose release from corn stover solids pretreated by leading technologies
journal, February 2009

  • Kumar, Rajeev; Wyman, C. E.
  • Biotechnology and Bioengineering, Vol. 102, Issue 2, p. 457-467
  • DOI: 10.1002/bit.22068

Lignin Valorization: Improving Lignin Processing in the Biorefinery
journal, May 2014

  • Ragauskas, A. J.; Beckham, G. T.; Biddy, M. J.
  • Science, Vol. 344, Issue 6185, p. 1246843-1246843
  • DOI: 10.1126/science.1246843

Cellulose accessibility limits the effectiveness of minimum cellulase loading on the efficient hydrolysis of pretreated lignocellulosic substrates
journal, January 2011

  • Arantes, Valdeir; Saddler, Jack N.
  • Biotechnology for Biofuels, Vol. 4, Issue 1, Article No. 3
  • DOI: 10.1186/1754-6834-4-3

Hydrochloric acid-catalyzed levulinic acid formation from cellulose: data and kinetic model to maximize yields
journal, March 2011

  • Shen, Jiacheng; Wyman, Charles E.
  • AIChE Journal, Vol. 58, Issue 1, p. 236-246
  • DOI: 10.1002/aic.12556

Pretreatment technologies for an efficient bioethanol production process based on enzymatic hydrolysis: A review
journal, July 2010

Features of promising technologies for pretreatment of lignocellulosic biomass
journal, April 2005

High-throughput screening for ionic liquids dissolving (ligno-)cellulose
journal, May 2009

Perspectives of microbial oils for biodiesel production
journal, August 2008

  • Li, Qiang; Du, Wei; Liu, Dehua
  • Applied Microbiology and Biotechnology, Vol. 80, Issue 5, p. 749-756
  • DOI: 10.1007/s00253-008-1625-9

An Oxidative Enzyme Boosting the Enzymatic Conversion of Recalcitrant Polysaccharides
journal, October 2010

  • Vaaje-Kolstad, Gustav; Westereng, Bj�rge; Horn, Svein J.
  • Science, Vol. 330, Issue 6001, p. 219-222
  • DOI: 10.1126/science.1192231

Bioproduction of butanol from biomass: from genes to bioreactors
journal, June 2007

  • Ezeji, Thaddeus Chukwuemeka; Qureshi, Nasib; Blaschek, Hans Peter
  • Current Opinion in Biotechnology, Vol. 18, Issue 3, p. 220-227
  • DOI: 10.1016/j.copbio.2007.04.002

Inhibition of cellulases by phenols
journal, March 2010

A Thermophilic Ionic Liquid-Tolerant Cellulase Cocktail for the Production of Cellulosic Biofuels
journal, May 2012

The path to next generation biofuels: successes and challenges in the era of synthetic biology
journal, January 2010

  • Dellomonaco, Clementina; Fava, Fabio; Gonzalez, Ramon
  • Microbial Cell Factories, Vol. 9, Issue 1, Article No. 3
  • DOI: 10.1186/1475-2859-9-3

Structural features affecting biomass enzymatic digestibility
journal, June 2008

Cellulase digestibility of pretreated biomass is limited by cellulose accessibility
journal, January 2007

  • Jeoh, Tina; Ishizawa, Claudia I.; Davis, Mark F.
  • Biotechnology and Bioengineering, Vol. 98, Issue 1, p. 112-122
  • DOI: 10.1002/bit.21408

Microbial hemicellulases
journal, June 2003

Methods for Pretreatment of Lignocellulosic Biomass for Efficient Hydrolysis and Biofuel Production
journal, April 2009

  • Kumar, Parveen; Barrett, Diane M.; Delwiche, Michael J.
  • Industrial & Engineering Chemistry Research, Vol. 48, Issue 8, p. 3713-3729
  • DOI: 10.1021/ie801542g

Dissolution of Cellose with Ionic Liquids
journal, May 2002

  • Swatloski, Richard P.; Spear, Scott K.; Holbrey, John D.
  • Journal of the American Chemical Society, Vol. 124, Issue 18, p. 4974-4975
  • DOI: 10.1021/ja025790m

Spontaneous High-Yield Production of Hydrogen from Cellulosic Materials and Water Catalyzed by Enzyme Cocktails
journal, February 2009

  • Ye, Xinhao; Wang, Yiran; Hopkins, Robert?C.
  • ChemSusChem, Vol. 2, Issue 2, p. 149-152
  • DOI: 10.1002/cssc.200900017

Conversion of biomass to sugars via ionic liquid hydrolysis: process synthesis and economic evaluation
journal, May 2012

  • Sen, S. Murat; Binder, Joseph B.; Raines, Ronald T.
  • Biofuels, Bioproducts and Biorefining, Vol. 6, Issue 4, p. 444-452
  • DOI: 10.1002/bbb.1336

Hydrolysis of lignocellulosic materials for ethanol production: a review
journal, May 2002

Improving enzymatic hydrolysis of wheat straw using ionic liquid 1-ethyl-3-methyl imidazolium diethyl phosphate pretreatment
journal, July 2009

Pretreatment of Lignocellulosic Wastes to Improve Ethanol and Biogas Production: A Review
journal, September 2008

  • Taherzadeh, Mohammad; Karimi, Keikhosro
  • International Journal of Molecular Sciences, Vol. 9, Issue 9, p. 1621-1651
  • DOI: 10.3390/ijms9091621

New Developments in Dissolving and Processing of Cellulose in Ionic Liquids
journal, February 2008

  • Hermanutz, Frank; G�hr, Frank; Uerdingen, Eric
  • Macromolecular Symposia, Vol. 262, Issue 1, p. 23-27
  • DOI: 10.1002/masy.200850203

Synthesis of three advanced biofuels from ionic liquid-pretreated switchgrass using engineered Escherichia coli
journal, November 2011

  • Bokinsky, G.; Peralta-Yahya, P. P.; George, A.
  • Proceedings of the National Academy of Sciences, Vol. 108, Issue 50, p. 19949-19954
  • DOI: 10.1073/pnas.1106958108

Toward an aggregated understanding of enzymatic hydrolysis of cellulose: Noncomplexed cellulase systems
journal, November 2004

  • Zhang, Yi-Heng Percival; Lynd, Lee R.
  • Biotechnology and Bioengineering, Vol. 88, Issue 7, p. 797-824
  • DOI: 10.1002/bit.20282

Supplementation with xylanase and ?-xylosidase to reduce xylo-oligomer and xylan inhibition of enzymatic hydrolysis of cellulose and pretreated corn stover
journal, June 2011

  • Qing, Qing; Wyman, Charles E.
  • Biotechnology for Biofuels, Vol. 4, Issue 1, Article No: 18
  • DOI: 10.1186/1754-6834-4-18

Microbial Cellulose Utilization: Fundamentals and Biotechnology
journal, September 2002

  • Lynd, L. R.; Weimer, P. J.; van Zyl, W. H.
  • Microbiology and Molecular Biology Reviews, Vol. 66, Issue 3, p. 506-577
  • DOI: 10.1128/MMBR.66.3.506-577.2002

Can ionic liquids dissolve wood? Processing and analysis of lignocellulosic materials with 1-n-butyl-3-methylimidazolium chloride
journal, January 2007

  • Fort, Diego A.; Remsing, Richard C.; Swatloski, Richard P.
  • Green Chemistry, Vol. 9, Issue 1, p. 63-69
  • DOI: 10.1039/B607614A