DNA reorganization in a mouse cell's nucleus

Program Document · 17 November 2016

OSTI ID:1475018

Berkeley Lab, LBNL

This visualization shows tightly-packed DNA in a mouse cell's nucleus at different stages of development, from its round shape as a multipotent stem cell; to a more oval shape as it develops into a more specialized neuronal progenitor; then a more triangular form as a mature nerve cell. The final, disjointed structure in this computerized rendering shows how removing a specialized binding protein (HP1β knockout) affects the structure of the DNA-packing material, called heterochromatin. (Credit: Berkeley Lab, UCSF)

• Research Organization: Lawrence Berkeley National Laboratory (LBNL), Berkeley, CA (United States)
• Sponsoring Organization: USDOE Office of Science (SC)
• DOE Contract Number: AC02-05CH11231
• OSTI ID: 1475018
• Country of Publication: United States
• Language: English