Insulin hexamer dissociation dynamics revealed by photoinduced T -jumps and time-resolved X-ray solution scattering
Abstract
The structural dynamics of insulin hexamer dissociation were studied by the photoinduced temperature jump technique and monitored by time-resolved X-ray scattering.
- Authors:
-
- Department of Chemistry; Northwestern University; Evanston; USA
- Department of Chemistry and Biochemistry; University of Delaware; Newark; USA
- Center for Advanced Radiation Sources; The University of Chicago; USA
- Department of Chemistry; Northwestern University; Evanston; USA; Chemical Sciences and Engineering Division
- Publication Date:
- Research Org.:
- Argonne National Lab. (ANL), Argonne, IL (United States)
- Sponsoring Org.:
- National Institutes of Health (NIH); USDOE Office of Science (SC), Basic Energy Sciences (BES)
- OSTI Identifier:
- 1471508
- DOE Contract Number:
- AC02-06CH11357
- Resource Type:
- Journal Article
- Journal Name:
- Photochemical & Photobiological Sciences
- Additional Journal Information:
- Journal Volume: 17; Journal Issue: 7; Journal ID: ISSN 1474-905X
- Publisher:
- Royal Society of Chemistry
- Country of Publication:
- United States
- Language:
- English
Citation Formats
Rimmerman, Dolev, Leshchev, Denis, Hsu, Darren J., Hong, Jiyun, Abraham, Baxter, Kosheleva, Irina, Henning, Robert, and Chen, Lin X. Insulin hexamer dissociation dynamics revealed by photoinduced T -jumps and time-resolved X-ray solution scattering. United States: N. p., 2018.
Web. doi:10.1039/c8pp00034d.
Rimmerman, Dolev, Leshchev, Denis, Hsu, Darren J., Hong, Jiyun, Abraham, Baxter, Kosheleva, Irina, Henning, Robert, & Chen, Lin X. Insulin hexamer dissociation dynamics revealed by photoinduced T -jumps and time-resolved X-ray solution scattering. United States. https://doi.org/10.1039/c8pp00034d
Rimmerman, Dolev, Leshchev, Denis, Hsu, Darren J., Hong, Jiyun, Abraham, Baxter, Kosheleva, Irina, Henning, Robert, and Chen, Lin X. 2018.
"Insulin hexamer dissociation dynamics revealed by photoinduced T -jumps and time-resolved X-ray solution scattering". United States. https://doi.org/10.1039/c8pp00034d.
@article{osti_1471508,
title = {Insulin hexamer dissociation dynamics revealed by photoinduced T -jumps and time-resolved X-ray solution scattering},
author = {Rimmerman, Dolev and Leshchev, Denis and Hsu, Darren J. and Hong, Jiyun and Abraham, Baxter and Kosheleva, Irina and Henning, Robert and Chen, Lin X.},
abstractNote = {The structural dynamics of insulin hexamer dissociation were studied by the photoinduced temperature jump technique and monitored by time-resolved X-ray scattering.},
doi = {10.1039/c8pp00034d},
url = {https://www.osti.gov/biblio/1471508},
journal = {Photochemical & Photobiological Sciences},
issn = {1474-905X},
number = 7,
volume = 17,
place = {United States},
year = {Mon Jan 01 00:00:00 EST 2018},
month = {Mon Jan 01 00:00:00 EST 2018}
}
Other availability
Save to My Library
You must Sign In or Create an Account in order to save documents to your library.
Works referenced in this record:
pH-dependent self-association of zinc-free insulin characterized by concentration-gradient static light scattering
journal, May 2010
- Attri, Arun K.; Fernández, Cristina; Minton, Allen P.
- Biophysical Chemistry, Vol. 148, Issue 1-3
Time-Resolved X-Ray Solution Scattering Reveals the Structural Photoactivation of a Light-Oxygen-Voltage Photoreceptor
journal, June 2017
- Berntsson, Oskar; Diensthuber, Ralph P.; Panman, Matthijs R.
- Structure, Vol. 25, Issue 6
Probing Cytochrome c Folding Transitions upon Phototriggered Environmental Perturbations Using Time-Resolved X-ray Scattering
journal, April 2018
- Rimmerman, Dolev; Leshchev, Denis; Hsu, Darren J.
- The Journal of Physical Chemistry B, Vol. 122, Issue 20
The structure of T 6 bovine insulin
journal, October 2005
- Smith, G. David; Pangborn, Walter A.; Blessing, Robert H.
- Acta Crystallographica Section D Biological Crystallography, Vol. 61, Issue 11
Microscopic Reversibility of Protein Folding in Molecular Dynamics Simulations of the Engrailed Homeodomain †
journal, July 2008
- McCully, Michelle E.; Beck, David A. C.; Daggett, Valerie
- Biochemistry, Vol. 47, Issue 27
Structure of human insulin monomer in water/acetonitrile solution
journal, November 2007
- Bocian, Wojciech; Sitkowski, Jerzy; Bednarek, Elżbieta
- Journal of Biomolecular NMR, Vol. 40, Issue 1
Advances in X-ray scattering: from solution SAXS to achievements with coherent beams
journal, October 2012
- Pérez, Javier; Nishino, Yoshinori
- Current Opinion in Structural Biology, Vol. 22, Issue 5
Application of Singular Value Decomposition to the Analysis of Time-Resolved Macromolecular X-Ray Data
journal, March 2003
- Schmidt, Marius; Rajagopal, Sudarshan; Ren, Zhong
- Biophysical Journal, Vol. 84, Issue 3
SVD-aided pseudo principal-component analysis: A new method to speed up and improve determination of the optimum kinetic model from time-resolved data
journal, July 2017
- Oang, Key Young; Yang, Cheolhee; Muniyappan, Srinivasan
- Structural Dynamics, Vol. 4, Issue 4
The role of assembly in insulin's biosynthesis
journal, April 1998
- Dodson, Guy; Steiner, Don
- Current Opinion in Structural Biology, Vol. 8, Issue 2
BioCARS: a synchrotron resource for time-resolved X-ray science
journal, May 2011
- Graber, T.; Anderson, S.; Brewer, H.
- Journal of Synchrotron Radiation, Vol. 18, Issue 4
Ferritin Assembly Revisited: A Time-Resolved Small-Angle X-ray Scattering Study
journal, January 2016
- Sato, Daisuke; Ohtomo, Hideaki; Yamada, Yoshiteru
- Biochemistry, Vol. 55, Issue 2
Conformational landscape of cytochrome c folding studied by microsecond-resolved small-angle x-ray scattering
journal, January 2002
- Akiyama, S.; Takahashi, S.; Kimura, T.
- Proceedings of the National Academy of Sciences, Vol. 99, Issue 3
Visualizing Solution-Phase Reaction Dynamics with Time-Resolved X-ray Liquidography
journal, February 2009
- Ihee, Hyotcherl
- Accounts of Chemical Research, Vol. 42, Issue 2
Laser Temperature Jump Induced Protein Refolding †
journal, November 1998
- Gruebele, Martin; Sabelko, Jobiah; Ballew, Richard
- Accounts of Chemical Research, Vol. 31, Issue 11
Direct Observation of Cooperative Protein Structural Dynamics of Homodimeric Hemoglobin from 100 ps to 10 ms with Pump–Probe X-ray Solution Scattering
journal, April 2012
- Kim, Kyung Hwan; Muniyappan, Srinivasan; Oang, Key Young
- Journal of the American Chemical Society, Vol. 134, Issue 16
Effect of Environmental Factors on the Kinetics of Insulin Fibril Formation: Elucidation of the Molecular Mechanism †
journal, May 2001
- Nielsen, Liza; Khurana, Ritu; Coats, Alisa
- Biochemistry, Vol. 40, Issue 20
Insulin Loaded PLGA Microspheres: Effect of Zinc Salts on Encapsulation, Release, and Stability
journal, February 2009
- Manoharan, Chandrasekar; Singh, Jagdish
- Journal of Pharmaceutical Sciences, Vol. 98, Issue 2
Prediction of the association state of insulin using spectral parameters
journal, April 2003
- Uversky, Vladimir N.; Garriques, Liza Nielsen; Millett, Ian S.
- Journal of Pharmaceutical Sciences, Vol. 92, Issue 4
Time-resolved photothermal methods: accessing time-resolved thermodynamics of photoinduced processes in chemistry and biologyDedicated to Professor Silvia Braslavsky, to mark her great contribution to photochemistry and photobiology particularly in the field of photothermal methods.
journal, January 2003
- Gensch, Thomas; Viappiani, Cristiano
- Photochemical & Photobiological Sciences, Vol. 2, Issue 7
Monitoring and Inhibition of Insulin Fibrillation by a Small Organic Fluorogen with Aggregation-Induced Emission Characteristics
journal, January 2012
- Hong, Yuning; Meng, Luming; Chen, Sijie
- Journal of the American Chemical Society, Vol. 134, Issue 3
Structural Characterisation and Functional Significance of Transient Protein–Protein Interactions
journal, January 2003
- Nooren, Irene M. A.; Thornton, Janet M.
- Journal of Molecular Biology, Vol. 325, Issue 5
Conformational Substates of Myoglobin Intermediate Resolved by Picosecond X-ray Solution Scattering
journal, February 2014
- Oang, Key Young; Kim, Jong Goo; Yang, Cheolhee
- The Journal of Physical Chemistry Letters, Vol. 5, Issue 5
Thermal Dissociation and Unfolding of Insulin
journal, August 2005
- Huus, Kasper; Havelund, Svend; Olsen, Helle B.
- Biochemistry, Vol. 44, Issue 33
Picosecond Photobiology: Watching a Signaling Protein Function in Real Time via Time-Resolved Small- and Wide-Angle X-ray Scattering
journal, July 2016
- Cho, Hyun Sun; Schotte, Friedrich; Dashdorj, Naranbaatar
- Journal of the American Chemical Society, Vol. 138, Issue 28
Insulin dimer dissociation and unfolding revealed by amide I two-dimensional infrared spectroscopy
journal, January 2010
- Ganim, Ziad; Jones, Kevin C.; Tokmakoff, Andrei
- Phys. Chem. Chem. Phys., Vol. 12, Issue 14
Transient 2D IR spectroscopy of ubiquitin unfolding dynamics
journal, June 2007
- Chung, H. S.; Ganim, Z.; Jones, K. C.
- Proceedings of the National Academy of Sciences, Vol. 104, Issue 36
Impulsive solvent heating probed by picosecond x-ray diffraction
journal, March 2006
- Cammarata, M.; Lorenc, M.; Kim, T. K.
- The Journal of Chemical Physics, Vol. 124, Issue 12
Anisotropic Picosecond X-ray Solution Scattering from Photoselectively Aligned Protein Molecules
journal, February 2011
- Kim, Jeongho; Kim, Kyung Hwan; Kim, Jong Goo
- The Journal of Physical Chemistry Letters, Vol. 2, Issue 5
Partially Folded Intermediates in Insulin Fibrillation †
journal, October 2003
- Ahmad, Atta; Millett, Ian S.; Doniach, Sebastian
- Biochemistry, Vol. 42, Issue 39
T HE F AST P ROTEIN F OLDING P ROBLEM
journal, October 1999
- Gruebele, M.
- Annual Review of Physical Chemistry, Vol. 50, Issue 1
Molecular dynamics simulations of unfolding and refolding of a -hairpin fragment of protein G
journal, August 1999
- Pande, V. S.; Rokhsar, D. S.
- Proceedings of the National Academy of Sciences, Vol. 96, Issue 16
A practical guide to small angle X-ray scattering (SAXS) of flexible and intrinsically disordered proteins
journal, August 2015
- Kikhney, Alexey G.; Svergun, Dmitri I.
- FEBS Letters, Vol. 589, Issue 19PartA
Direct Observation of Insulin Association Dynamics with Time-Resolved X-ray Scattering
journal, September 2017
- Rimmerman, Dolev; Leshchev, Denis; Hsu, Darren J.
- The Journal of Physical Chemistry Letters, Vol. 8, Issue 18
Sequential conformational transitions and α-helical supercoiling regulate a sensor histidine kinase
journal, August 2017
- Berntsson, Oskar; Diensthuber, Ralph P.; Panman, Matthijs R.
- Nature Communications, Vol. 8, Issue 1
Protein structural dynamics in solution unveiled via 100-ps time-resolved x-ray scattering
journal, April 2010
- Cho, H. S.; Dashdorj, N.; Schotte, F.
- Proceedings of the National Academy of Sciences, Vol. 107, Issue 16
Studying Protein–Protein Binding through T-Jump Induced Dissociation: Transient 2D IR Spectroscopy of Insulin Dimer
journal, May 2016
- Zhang, Xin-Xing; Jones, Kevin C.; Fitzpatrick, Ann
- The Journal of Physical Chemistry B, Vol. 120, Issue 23
Tracking the structural dynamics of proteins in solution using time-resolved wide-angle X-ray scattering
journal, September 2008
- Cammarata, Marco; Levantino, Matteo; Schotte, Friedrich
- Nature Methods, Vol. 5, Issue 10
Amyloid Fibrillation of Insulin under Water-Limited Conditions
journal, October 2014
- Choi, Tae Su; Lee, Jong Wha; Jin, Kyeong Sik
- Biophysical Journal, Vol. 107, Issue 8
Stimulation of Insulin Fibrillation by Urea-induced Intermediates
journal, January 2004
- Ahmad, Atta; Millett, Ian S.; Doniach, Sebastian
- Journal of Biological Chemistry, Vol. 279, Issue 15
Thermodynamics of Formation of the Insulin Hexamer: Metal-Stabilized Proton-Coupled Assembly of Quaternary Structure
journal, February 2014
- Carpenter, Margaret C.; Wilcox, Dean E.
- Biochemistry, Vol. 53, Issue 8
Protein Structural Dynamics of Photoactive Yellow Protein in Solution Revealed by Pump–Probe X-ray Solution Scattering
journal, February 2012
- Kim, Tae Wu; Lee, Jae Hyuk; Choi, Jungkweon
- Journal of the American Chemical Society, Vol. 134, Issue 6
Protein folding and unfolding on a complex energy landscape
journal, February 2000
- Leeson, D. T.; Gai, F.; Rodriguez, H. M.
- Proceedings of the National Academy of Sciences, Vol. 97, Issue 6
Multimerization and Aggregation of Native-State Insulin: Effect of Zinc
journal, December 2011
- Xu, Yisheng; Yan, Yunfeng; Seeman, Daniel
- Langmuir, Vol. 28, Issue 1
Unifying features in protein-folding mechanisms
journal, October 2003
- Gianni, S.; Guydosh, N. R.; Khan, F.
- Proceedings of the National Academy of Sciences, Vol. 100, Issue 23
Characterization of the nanoscale properties of individual amyloid fibrils
journal, October 2006
- Smith, J. F.; Knowles, T. P. J.; Dobson, C. M.
- Proceedings of the National Academy of Sciences, Vol. 103, Issue 43
Time-resolved methods in biophysics. 9. Laser temperature-jump methods for investigating biomolecular dynamics
journal, January 2009
- Kubelka, Jan
- Photochemical & Photobiological Sciences, Vol. 8, Issue 4
Protein Folding and Unfolding at Atomic Resolution
journal, February 2002
- Fersht, Alan R.; Daggett, Valerie
- Cell, Vol. 108, Issue 4