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De novo design of allosteric proteins

Patent ·
OSTI ID:1469336
Methods and compositions for making and isolating allosteric DNA binding proteins that bind to one or more allosteric effectors to induce a conformation change in the proteins are provided.
Research Organization:
Harvard College, Cambridge, MA (United States)
Sponsoring Organization:
USDOE
DOE Contract Number:
FG02-02ER63445
Assignee:
President and Fellows of Harvard College (Cambridge, MA)
Patent Number(s):
10,041,065
Application Number:
15/628,690
OSTI ID:
1469336
Country of Publication:
United States
Language:
English

References (2)

The structural basis of allosteric regulation in proteins journal March 2009
Light-activated DNA binding in a designed allosteric protein journal July 2008

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