Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability

Iglesias, Nahid; Currie, Mark A.; Jih, Gloria; Paulo, Joao A.; Siuti, Nertila; Kalocsay, Marian; Gygi, Steven P.; Moazed, Danesh

doi:10.1038/s41586-018-0398-2

Automethylation-induced conformational switch in Clr4 (Suv39h) maintains epigenetic stability

Journal Article · 23 July 2018 · Nature (London)

DOI:https://doi.org/10.1038/s41586-018-0398-2· OSTI ID:1468812

Iglesias, Nahid; Currie, Mark A.; Jih, Gloria; Paulo, Joao A.; Siuti, Nertila; Kalocsay, Marian; Gygi, Steven P.; Moazed, Danesh

Research Organization:: Argonne National Lab. (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: NIHFOREIGNHHMI

OSTI ID:: 1468812

Journal Information:: Nature (London), Vol. 560, Issue 7719; ISSN 0028-0836

Publisher:: Nature Publishing Group

Country of Publication:: United States

Language:: ENGLISH

References (37)

Selective recognition of methylated lysine 9 on histone H3 by the HP1 chromo domain Bannister, Andrew J.; Zegerman, Philip; Partridge, Janet F. Nature, Vol. 410, Issue 6824 https://doi.org/10.1038/35065138	journal	March 2001
Epe1 recruits BET family bromodomain protein Bdf2 to establish heterochromatin boundaries Wang, J.; Tadeo, X.; Hou, H. Genes & Development, Vol. 27, Issue 17 https://doi.org/10.1101/gad.221010.113	journal	September 2013
Overview of the CCP 4 suite and current developments Winn, Martyn D.; Ballard, Charles C.; Cowtan, Kevin D. Acta Crystallographica Section D Biological Crystallography, Vol. 67, Issue 4 https://doi.org/10.1107/S0907444910045749	journal	March 2011
Methylation of histone H3 lysine 9 creates a binding site for HP1 proteins Lachner, Monika; O'Carroll, Dónal; Rea, Stephen Nature, Vol. 410, Issue 6824 https://doi.org/10.1038/35065132	journal	March 2001
Epigenetic inheritance uncoupled from sequence-specific recruitment Ragunathan, Kaushik; Jih, Gloria; Moazed, Danesh Science, Vol. 348, Issue 6230 https://doi.org/10.1126/science.1258699	journal	November 2014
Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks Southall, Stacey M.; Wong, Poon-Sheng; Odho, Zain Molecular Cell, Vol. 33, Issue 2 https://doi.org/10.1016/j.molcel.2008.12.029	journal	January 2009
Structural basis for activity regulation of MLL family methyltransferases Li, Yanjing; Han, Jianming; Zhang, Yuebin Nature, Vol. 530, Issue 7591 https://doi.org/10.1038/nature16952	journal	February 2016
Dynamics of epigenetic regulation at the single-cell level Bintu, L.; Yong, J.; Antebi, Y. E. Science, Vol. 351, Issue 6274 https://doi.org/10.1126/science.aab2956	journal	February 2016
Dynamics and Memory of Heterochromatin in Living Cells Hathaway, Nathaniel A.; Bell, Oliver; Hodges, Courtney Cell, Vol. 149, Issue 7 https://doi.org/10.1016/j.cell.2012.03.052	journal	June 2012
Collaboration gets the most out of software Morin, Andrew; Eisenbraun, Ben; Key, Jason eLife, Vol. 2 https://doi.org/10.7554/eLife.01456	journal	September 2013
Division of Labor between the Chromodomains of HP1 and Suv39 Methylase Enables Coordination of Heterochromatin Spread Al-Sady, Bassem; Madhani, Hiten D.; Narlikar, Geeta J. Molecular Cell, Vol. 51, Issue 1 https://doi.org/10.1016/j.molcel.2013.06.013	journal	July 2013
Features and development of Coot Emsley, P.; Lohkamp, B.; Scott, W. G. Acta Crystallographica Section D Biological Crystallography, Vol. 66, Issue 4 https://doi.org/10.1107/S0907444910007493	journal	March 2010
Heterologous modules for efficient and versatile PCR-based gene targeting inSchizosaccharomyces pombe Bähler, Jürg; Wu, Jian-Qiu; Longtine, Mark S. Yeast, Vol. 14, Issue 10 https://doi.org/10.1002/(SICI)1097-0061(199807)14:10<943::AID-YEA292>3.0.CO;2-Y	journal	July 1998
Role of Histone H3 Lysine 9 Methylation in Epigenetic Control of Heterochromatin Assembly Nakayama, J. -i. Science, Vol. 292, Issue 5514 https://doi.org/10.1126/science.1060118	journal	March 2001
Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription Jih, Gloria; Iglesias, Nahid; Currie, Mark A. Nature, Vol. 547, Issue 7664 https://doi.org/10.1038/nature23267	journal	June 2017
Mechanisms for the Inheritance of Chromatin States Moazed, Danesh Cell, Vol. 146, Issue 4 https://doi.org/10.1016/j.cell.2011.07.013	journal	August 2011
Regulation of Heterochromatic Silencing and Histone H3 Lysine-9 Methylation by RNAi Volpe, T. A. Science, Vol. 297, Issue 5588 https://doi.org/10.1126/science.1074973	journal	August 2002
A Triple Knockout (TKO) Proteomics Standard for Diagnosing Ion Interference in Isobaric Labeling Experiments Paulo, Joao A.; O’Connell, Jeremy D.; Gygi, Steven P. Journal of The American Society for Mass Spectrometry, Vol. 27, Issue 10 https://doi.org/10.1007/s13361-016-1434-9	journal	July 2016
A probability-based approach for high-throughput protein phosphorylation analysis and site localization Beausoleil, Sean A.; Villén, Judit; Gerber, Scott A. Nature Biotechnology, Vol. 24, Issue 10 https://doi.org/10.1038/nbt1240	journal	September 2006
Principles of CDK regulation Morgan, David O. Nature, Vol. 374, Issue 6518 https://doi.org/10.1038/374131a0	journal	March 1995
DNA sequence-dependent epigenetic inheritance of gene silencing and histone H3K9 methylation Wang, Xiaoyi; Moazed, Danesh Science, Vol. 356, Issue 6333 https://doi.org/10.1126/science.aaj2114	journal	March 2017
Swi6/HP1 Recruits a JmjC Domain Protein to Facilitate Transcription of Heterochromatic Repeats Zofall, Martin; Grewal, Shiv I. S. Molecular Cell, Vol. 22, Issue 5 https://doi.org/10.1016/j.molcel.2006.05.010	journal	June 2006
The JmjC domain protein Epe1 prevents unregulated assembly and disassembly of heterochromatin Trewick, Sarah C.; Minc, Elsa; Antonelli, Richard The EMBO Journal, Vol. 26, Issue 22 https://doi.org/10.1038/sj.emboj.7601892	journal	October 2007
Structure, mechanism, and regulation of polycomb-repressive complex 2 Moritz, Lindsay E.; Trievel, Raymond C. Journal of Biological Chemistry, Vol. 293, Issue 36 https://doi.org/10.1074/jbc.R117.800367	journal	September 2017
A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression Huttlin, Edward L.; Jedrychowski, Mark P.; Elias, Joshua E. Cell, Vol. 143, Issue 7 https://doi.org/10.1016/j.cell.2010.12.001	journal	December 2010
Roles of the Clr4 methyltransferase complex in nucleation, spreading and maintenance of heterochromatin Zhang, Ke; Mosch, Kerstin; Fischle, Wolfgang Nature Structural & Molecular Biology, Vol. 15, Issue 4 https://doi.org/10.1038/nsmb.1406	journal	March 2008
Restricted epigenetic inheritance of H3K9 methylation Audergon, Pauline N. C. B.; Catania, Sandra; Kagansky, Alexander Science, Vol. 348, Issue 6230 https://doi.org/10.1126/science.1260638	journal	April 2015
Rapid epigenetic adaptation to uncontrolled heterochromatin spreading Wang, Jiyong; Reddy, Bharat D.; Jia, Songtao eLife, Vol. 4 https://doi.org/10.7554/eLife.06179	journal	March 2015
MS3 eliminates ratio distortion in isobaric multiplexed quantitative proteomics Ting, Lily; Rad, Ramin; Gygi, Steven P. Nature Methods, Vol. 8, Issue 11 https://doi.org/10.1038/nmeth.1714	journal	October 2011
Proteome-wide quantitative multiplexed profiling of protein expression: carbon-source dependency in Saccharomyces cerevisiae Paulo, Joao A.; O’Connell, Jeremy D.; Gaun, Aleksandr Molecular Biology of the Cell, Vol. 26, Issue 22 https://doi.org/10.1091/mbc.e15-07-0499	journal	November 2015
Structural Basis for the Product Specificity of Histone Lysine Methyltransferases Zhang, Xing; Yang, Zhe; Khan, Seema I. Molecular Cell, Vol. 12, Issue 1 https://doi.org/10.1016/S1097-2765(03)00224-7	journal	July 2003
Phaser crystallographic software McCoy, Airlie J.; Grosse-Kunstleve, Ralf W.; Adams, Paul D. Journal of Applied Crystallography, Vol. 40, Issue 4 https://doi.org/10.1107/S0021889807021206	journal	July 2007
MultiNotch MS3 Enables Accurate, Sensitive, and Multiplexed Detection of Differential Expression across Cancer Cell Line Proteomes McAlister, Graeme C.; Nusinow, David P.; Jedrychowski, Mark P. Analytical Chemistry, Vol. 86, Issue 14 https://doi.org/10.1021/ac502040v	journal	July 2014
Regulation of chromatin structure by site-specific histone H3 methyltransferases Rea, Stephen; Eisenhaber, Frank; O'Carroll, Dónal Nature, Vol. 406, Issue 6796 https://doi.org/10.1038/35020506	journal	August 2000
Ubiquitin-mediated mRNP dynamics and surveillance prior to budding yeast mRNA export Iglesias, N.; Tutucci, E.; Gwizdek, C. Genes & Development, Vol. 24, Issue 17 https://doi.org/10.1101/gad.583310	journal	September 2010
Structural Biology of Human H3K9 Methyltransferases Wu, Hong; Min, Jinrong; Lunin, Vladimir V. PLoS ONE, Vol. 5, Issue 1 https://doi.org/10.1371/journal.pone.0008570	journal	January 2010
A histone H3K9M mutation traps histone methyltransferase Clr4 to prevent heterochromatin spreading Shan, Chun-Min; Wang, Jiyong; Xu, Ke eLife, Vol. 5 https://doi.org/10.7554/eLife.17903	journal	September 2016

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