Inosine 5′-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo
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journal
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April 2004 |
A generic approach for the catalytic reduction of nitriles
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journal
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July 2003 |
A Regulatory Role of the Bateman Domain of IMP Dehydrogenase in Adenylate Nucleotide Biosynthesis
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journal
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March 2009 |
A Screening Pipeline for Antiparasitic Agents Targeting Cryptosporidium Inosine Monophosphate Dehydrogenase
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journal
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August 2010 |
Comprehensive analysis of methods used for the evaluation of compounds against Mycobacterium tuberculosis
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journal
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November 2012 |
Crystal Structure of a Ternary Complex of Tritrichomonas foetus Inosine 5‘-Monophosphate Dehydrogenase: NAD + Orients the Active Site Loop for Catalysis † , ‡
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journal
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November 2002 |
Synthesis, in Vitro Evaluation and Cocrystal Structure of 4-Oxo-[1]benzopyrano[4,3- c ]pyrazole Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase ( Cp IMPDH) Inhibitors
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journal
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December 2014 |
Benzoxazoles, Phthalazinones, and Arylurea-Based Compounds with IMP Dehydrogenase-Independent Antibacterial Activity against Francisella tularensis
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journal
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October 2017 |
The Structural Basis of Cryptosporidium-Specific IMP Dehydrogenase Inhibitor Selectivity
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journal
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February 2010 |
Comprehensive Essentiality Analysis of the Mycobacterium tuberculosis Genome via Saturating Transposon Mutagenesis
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journal
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January 2017 |
MgATP Regulates Allostery and Fiber Formation in IMPDHs
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journal
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June 2013 |
Triazole Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
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journal
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August 2009 |
Targeting a Prokaryotic Protein in a Eukaryotic Pathogen: Identification of Lead Compounds against Cryptosporidiosis
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journal
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January 2008 |
The Antibiotic Potential of Prokaryotic IMP Dehydrogenase Inhibitors
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journal
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May 2011 |
Phthalazinone inhibitors of inosine-5′-monophosphate dehydrogenase from Cryptosporidium parvum
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journal
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February 2013 |
Benzoxaborole antimalarial agents. Part 2: Discovery of fluoro-substituted 7-(2-carboxyethyl)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles
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journal
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February 2012 |
Acquired Resistance to Bedaquiline and Delamanid in Therapy for Tuberculosis
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journal
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November 2015 |
Genes required for mycobacterial growth defined by high density mutagenesis: Genes required for mycobacterial growth
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journal
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March 2003 |
Two Classes of Bacterial IMPDHs according to Their Quaternary Structures and Catalytic Properties
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journal
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February 2015 |
IMP Dehydrogenase: Structure, Mechanism, and Inhibition
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journal
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July 2009 |
Identification of Novel Mt-Guab2 Inhibitor Series Active against M. tuberculosis
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journal
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March 2012 |
Novel inhibitors of Mycobacterium tuberculosis GuaB2 identified by a target based high-throughput phenotypic screen
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journal
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December 2016 |
Crystallographic studies of two variants of Pseudomonas aeruginosa IMPDH with impaired allosteric regulation
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journal
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August 2015 |
Bacillus anthracis Inosine 5′-Monophosphate Dehydrogenase in Action: The First Bacterial Series of Structures of Phosphate Ion-, Substrate-, and Product-Bound Complexes
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journal
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July 2012 |
The Inosine Monophosphate Dehydrogenase, GuaB2, Is a Vulnerable New Bactericidal Drug Target for Tuberculosis
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journal
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September 2016 |
Essential but Not Vulnerable: Indazole Sulfonamides Targeting Inosine Monophosphate Dehydrogenase as Potential Leads against Mycobacterium tuberculosis
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journal
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October 2016 |
Repurposing Cryptosporidium Inosine 5′-Monophosphate Dehydrogenase Inhibitors as Potential Antibacterial Agents
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journal
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June 2014 |
UCSF Chimera?A visualization system for exploratory research and analysis
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journal
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January 2004 |
Structure–activity relationship study of selective benzimidazole-based inhibitors of Cryptosporidium parvum IMPDH
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journal
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March 2012 |
Metabolic Enzyme IMPDH Is Also a Transcription Factor Regulated by Cellular State
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journal
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July 2012 |
A Novel Cofactor-binding Mode in Bacterial IMP Dehydrogenases Explains Inhibitor Selectivity
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journal
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January 2015 |
The CBS subdomain of inosine 5′-monophosphate dehydrogenase regulates purine nucleotide turnover: CBS subdomain of IMPDH
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journal
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February 2008 |
The Bare Essentials of Antibiotic Target Validation
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journal
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November 2016 |
Optimization of Benzoxazole-Based Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
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journal
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May 2013 |
Transition-Metal-Free Hydration of Nitriles Using Potassium tert -Butoxide under Anhydrous Conditions
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journal
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March 2015 |
The dynamic determinants of reaction specificity in the IMPDH/GMPR family of (β/α) 8 barrel enzymes
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journal
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January 2012 |
Mapping the Protein Interaction Network in Methicillin-Resistant Staphylococcus aureus
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journal
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March 2011 |
Pathway-Selective Sensitization of Mycobacterium tuberculosis for Target-Based Whole-Cell Screening
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journal
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July 2012 |
Guanine nucleotide binding to the Bateman domain mediates the allosteric inhibition of eukaryotic IMP dehydrogenases
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journal
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November 2015 |
CBS domains: structure, function, and pathology in human proteins
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journal
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December 2005 |
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
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journal
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October 2016 |
Triazole-Linked Inhibitors of Inosine Monophosphate Dehydrogenase from Human and Mycobacterium tuberculosis
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journal
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June 2010 |
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
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journal
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June 1998 |
Interaction network containing conserved and essential protein complexes in Escherichia coli
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journal
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February 2005 |
The Complex Mechanism of Antimycobacterial Action of 5-Fluorouracil
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journal
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January 2015 |
IMP Dehydrogenase Type 1 Associates with Polyribosomes Translating Rhodopsin mRNA
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journal
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December 2008 |
Biochemical Analysis of the Modular Enzyme Inosine 5′-Monophosphate Dehydrogenase
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journal
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November 1999 |
Identification of novel diphenyl urea inhibitors of Mt-GuaB2 active against Mycobacterium tuberculosis
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journal
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January 2011 |
Selective and Potent Urea Inhibitors of Cryptosporidium parvum Inosine 5′-Monophosphate Dehydrogenase
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journal
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September 2012 |
Hit and lead criteria in drug discovery for infectious diseases of the developing world
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journal
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October 2015 |
Mycobacterium tuberculosis IMPDH in Complexes with Substrates, Products and Antitubercular Compounds
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journal
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October 2015 |
IMP Dehydrogenase: Mechanism of Action and Inhibition
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journal
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July 1999 |