Cellobiohydrolase variants and polynucleotides encoding same

Wogulis, Mark

Cellobiohydrolase variants and polynucleotides encoding same

Patent · 31 July 2018

OSTI ID:1464740

Wogulis, Mark

The present invention relates to cellobiohydrolase variants. The present invention also relates to polynucleotides encoding the variants; nucleic acid constructs, vectors, and host cells comprising the polynucleotides; and methods of producing and using the variants.

Research Organization:: Novozymes, Inc., Davis, CA (United States)

Sponsoring Organization:: USDOE

DOE Contract Number:: FC36-08GO18080

Assignee:: Novozymes, Inc. (Davis, CA)

Patent Number(s):: 10,036,050

Application Number:: 14/367,182

OSTI ID:: 1464740

Country of Publication:: United States

Language:: English

References (11)

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Molecular cloning, transcriptional, and expression analysis of the first cellulase gene (cbh2), encoding cellobiohydrolase II, from the moderately thermophilic fungus Talaromyces emersonii and structure prediction of the gene product Murray, P. G.; Collins, C. M.; Grassick, A. Biochemical and Biophysical Research Communications, Vol. 301, Issue 2, p. 280-286 https://doi.org/10.1016/S0006-291X(02)03025-5	journal	February 2003
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Semi-rational approaches to engineering enzyme activity: combining the benefits of directed evolution and rational design Chica, Roberto A.; Doucet, Nicolas; Pelletier, Joelle N. Current Opinion in Biotechnology, Vol. 16, Issue 4, p. 378-384 https://doi.org/10.1016/j.copbio.2005.06.004	journal	August 2005
Distributions of structural features contributing to thermostability in mesophilic and thermophilic α/β barrel glycosyl hydrolases Panasik, Nicholas; Brenchley, Jean E.; Farber, Gregory K. Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology, Vol. 1543, Issue 1, p. 189-201 https://doi.org/10.1016/S0167-4838(00)00182-5	journal	November 2000
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