Functional analysis of conserved cis- and trans-elements in the Hsp104 protein disaggregating machine
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journal
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August 2012 |
Coordinated Hsp110 and Hsp104 Activities Power Protein Disaggregation in Saccharomyces cerevisiae
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journal
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March 2017 |
Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation
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journal
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August 2012 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution.
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text
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January 2010 |
Escherichia coli ClpB is a non-processive polypeptide translocase
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journal
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August 2015 |
Loops in the Central Channel of ClpA Chaperone Mediate Protein Binding, Unfolding, and Translocation
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journal
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July 2005 |
AAA+ Proteases: ATP-Fueled Machines of Protein Destruction
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journal
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July 2011 |
Role of the GYVG Pore Motif of HslU ATPase in Protein Unfolding and Translocation for Degradation by HslV Peptidase
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journal
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April 2005 |
Ratchet-like polypeptide translocation mechanism of the AAA+ disaggregase Hsp104
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journal
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June 2017 |
Protein rescue from aggregates by powerful molecular chaperone machines
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journal
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September 2013 |
Overlapping and Specific Functions of the Hsp104 N Domain Define Its Role in Protein Disaggregation
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journal
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September 2017 |
Inorganic phosphate assay with malachite green: An improvement and evaluation
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journal
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December 1982 |
In Vivo Monitoring of the Prion Replication Cycle Reveals a Critical Role for Sis1 in Delivering Substrates to Hsp104
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journal
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November 2008 |
Species-specific collaboration of heat shock proteins (Hsp) 70 and 100 in thermotolerance and protein disaggregation
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journal
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April 2011 |
Quantitative method for the assignment of hinge and shear mechanism in protein domain movements
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journal
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July 2014 |
Insights into Hsp70 Chaperone Activity from a Crystal Structure of the Yeast Hsp110 Sse1
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journal
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October 2007 |
Hsp104, Hsp70, and Hsp40
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journal
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July 1998 |
Structures of Asymmetric ClpX Hexamers Reveal Nucleotide-Dependent Motions in a AAA+ Protein-Unfolding Machine
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journal
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November 2009 |
Substrate recognition by the AAA+ chaperone ClpB
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journal
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June 2004 |
Towards a unifying mechanism for ClpB/Hsp104-mediated protein disaggregation and prion propagationThis paper is one of a selection of papers published in this special issue entitled 8th International Conference on AAA Proteins and has undergone the Journal's usual peer review process.
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journal
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February 2010 |
Thermotolerance Requires Refolding of Aggregated Proteins by Substrate Translocation through the Central Pore of ClpB
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journal
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November 2004 |
Heat shock protein (Hsp) 70 is an activator of the Hsp104 motor
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journal
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May 2013 |
Crystal Structure of E.coli Hsp100 ClpB Nucleotide-binding Domain 1 (NBD1) and Mechanistic Studies on ClpB ATPase Activity
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journal
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May 2002 |
Structural basis for the disaggregase activity and regulation of Hsp104
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journal
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November 2016 |
The M-Domain Controls Hsp104 Protein Remodeling Activity in an Hsp70/Hsp40-Dependent Manner
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journal
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September 2010 |
Mutational studies on HslU and its docking mode with HslV
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journal
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December 2000 |
Mechanistic and Structural Insights into the Prion-Disaggregase Activity of Hsp104
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journal
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May 2016 |
Crystal and Solution Structures of an HslUV Protease–Chaperone Complex
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journal
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November 2000 |
Peptide and Protein Binding in the Axial Channel of Hsp104: INSIGHTS INTO THE MECHANISM OF PROTEIN UNFOLDING
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journal
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August 2008 |
Cavin1 intrinsically disordered domains are essential for fuzzy electrostatic interactions and caveola formation
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journal
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February 2021 |
Spiral architecture of the Hsp104 disaggregase reveals the basis for polypeptide translocation
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journal
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August 2016 |
Coot model-building tools for molecular graphics
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journal
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November 2004 |
Saccharomyces cerevisiae Hsp104 Enhances the Chaperone Capacity of Human Cells and Inhibits Heat Stress-Induced Proapoptotic Signaling †
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journal
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June 2004 |
The Hsp104 N-Terminal Domain Enables Disaggregase Plasticity and Potentiation
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journal
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March 2015 |
Conformational Properties of Aggregated Polypeptides Determine ClpB-dependence in the Disaggregation Process
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journal
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August 2007 |
CryoEM structure of Hsp104 and its mechanistic implication for protein disaggregation
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journal
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April 2010 |
N-Terminal Domain of Yeast Hsp104 Chaperone Is Dispensable for Thermotolerance and Prion Propagation but Necessary for Curing Prions by Hsp104 Overexpression
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journal
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April 2006 |
PHENIX: a comprehensive Python-based system for macromolecular structure solution
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journal
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January 2010 |
DnaK Chaperone-dependent Disaggregation by Caseinolytic Peptidase B (ClpB) Mutants Reveals Functional Overlap in the N-terminal Domain and Nucleotide-binding Domain-1 Pore Tyrosine
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journal
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June 2012 |
Crystal Structures of the HslVU Peptidase–ATPase Complex Reveal an ATP-Dependent Proteolysis Mechanism
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journal
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February 2001 |
Cooperation of Hsp70 and Hsp100 chaperone machines in protein disaggregation
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journal
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May 2015 |
Crystal structures of Hsp104 N-terminal domains from Saccharomyces cerevisiae and Candida albicans suggest the mechanism for the function of Hsp104 in dissolving prions
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journal
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March 2017 |
Structural pathway of regulated substrate transfer and threading through an Hsp100 disaggregase
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journal
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August 2017 |
NMRPipe: A multidimensional spectral processing system based on UNIX pipes
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journal
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November 1995 |
Role of the processing pore of the ClpX AAA+ ATPase in the recognition and engagement of specific protein substrates
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journal
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February 2004 |
Controlled destruction: AAA+ ATPases in protein degradation from bacteria to eukaryotes
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journal
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April 2009 |
Evidence for an Unfolding/Threading Mechanism for Protein Disaggregation by Saccharomyces cerevisiae Hsp104
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journal
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May 2004 |
MOLREP an Automated Program for Molecular Replacement
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journal
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December 1997 |
Structure and mechanism of the hexameric MecA–ClpC molecular machine
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journal
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March 2011 |
[20] Processing of X-ray diffraction data collected in oscillation mode
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book
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January 1997 |
Structure of the cross-β spine of amyloid-like fibrils
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journal
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June 2005 |
Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation
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journal
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April 2008 |
Saccharomyces cerevisiae Hsp104 protein. Purification and characterization of ATP-induced structural changes.
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journal
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February 1994 |
Genetic and Environmental Factors Affecting the de novo Appearance of the [PSI +
] Prion in Saccharomyces cerevisiae
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journal
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October 1997 |