Crystal structures of amyloidogenic segments of human transthyretin: Amyloid Structures of Transthyretin Segments

Saelices, Lorena; Sievers, Stuart A.; Sawaya, Michael R.; Eisenberg, David S.

doi:10.1002/pro.3420

Title: Crystal structures of amyloidogenic segments of human transthyretin: Amyloid Structures of Transthyretin Segments

Authors:

^[1]; Sievers, Stuart A. ^[1]; Sawaya, Michael R. ^[1]; Eisenberg, David S. ^[1]

Departments of Biological Chemistry and Chemistry and Biochemistry, Molecular Biology Institute, Box 951570, UCLA, Howard Hughes Medical Institute, UCLA-DOE Institute, Los Angeles California 90095-1570

Publication Date:: Wed Jun 13 00:00:00 EDT 2018

Research Org.:: Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Org.:: UNIVERSITY

OSTI Identifier:: 1459976

Resource Type:: Journal Article

Journal Name:: Protein Science

Additional Journal Information:: Journal Volume: 27; Journal Issue: 7; Journal ID: ISSN 0961-8368

Publisher:: The Protein Society

Country of Publication:: United States

Language:: ENGLISH

Citation Formats


                    Saelices, Lorena, Sievers, Stuart A., Sawaya, Michael R., and Eisenberg, David S. Crystal structures of amyloidogenic segments of human transthyretin: Amyloid Structures of Transthyretin Segments.  United States: N. p., 2018. 
        Web.  doi:10.1002/pro.3420.

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                    Saelices, Lorena, Sievers, Stuart A., Sawaya, Michael R., & Eisenberg, David S. Crystal structures of amyloidogenic segments of human transthyretin: Amyloid Structures of Transthyretin Segments.  United States.  https://doi.org/10.1002/pro.3420

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                    Saelices, Lorena, Sievers, Stuart A., Sawaya, Michael R., and Eisenberg, David S. 2018.  
        "Crystal structures of amyloidogenic segments of human transthyretin: Amyloid Structures of Transthyretin Segments".  United States.  https://doi.org/10.1002/pro.3420.

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@article{osti_1459976,

  title        = {Crystal structures of amyloidogenic segments of human transthyretin: Amyloid Structures of Transthyretin Segments},

  author       = {Saelices, Lorena and Sievers, Stuart A. and Sawaya, Michael R. and Eisenberg, David S.},

  abstractNote = {},

  doi          = {10.1002/pro.3420},

  url          = {https://www.osti.gov/biblio/1459976},
  journal      = {Protein Science},

  issn         = {0961-8368},

  number       = 7,

  volume       = 27,

  place        = {United States},

  year         = {Wed Jun 13 00:00:00 EDT 2018},

  month        = {Wed Jun 13 00:00:00 EDT 2018}

}

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Title: Crystal structures of amyloidogenic segments of human transthyretin: Amyloid Structures of Transthyretin Segments

Citation Formats

Out-of-register -sheets suggest a pathway to toxic amyloid aggregates journal, December 2012

Shape Complementarity at Protein/Protein Interfaces journal, December 1993

The Amyloid State of Proteins in Human Diseases journal, March 2012

Structural Studies of Amyloid Proteins at the Molecular Level journal, June 2017

Refinement of Macromolecular Structures by the Maximum-Likelihood Method journal, May 1997

Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology journal, January 2005

Molecular basis for amyloid- polymorphism journal, September 2011

Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS) journal, July 2017

Transthyretin (Prealbumin) in Health and Disease: Nutritional Implications journal, July 1994

Identifying the amylome, proteins capable of forming amyloid-like fibrils journal, February 2010

Solvent-accessible surfaces of proteins and nucleic acids journal, August 1983

Diagnosis, Prognosis, and Therapy of Transthyretin Amyloidosis journal, December 2015

Atomic structure and hierarchical assembly of a cross- amyloid fibril journal, March 2013

Atomic structures of amyloid cross-β spines reveal varied steric zippers journal, April 2007

Relaxation of backbone bond geometry improves protein energy landscape modeling: Relaxation of Backbone Bond Geometry journal, November 2013

Structure of prealbumin: Secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 Å journal, May 1978

Structure-based inhibitors of tau aggregation journal, November 2017

Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage journal, January 2015

Atomic View of a Toxic Amyloid Small Oligomer journal, March 2012

The interpretation of protein structures: Estimation of static accessibility journal, February 1971

Common core structure of amyloid fibrils by synchrotron X-ray diffraction 1 1Edited by F. E. Cohen journal, October 1997

Molecular mechanisms for protein-encoded inheritance journal, August 2009

Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets journal, January 2016

Automated Structure Solution with the PHENIX Suite book, January 2008

The 3D profile method for identifying fibril-forming segments of proteins journal, March 2006

Structure of the cross-β spine of amyloid-like fibrils journal, June 2005

Phaser crystallographic software journal, July 2007

A new amyloidogenic transthyretin variant, [D38A], detected by electrospray ionization / mass spectrometry journal, January 1999

Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients journal, September 2017

Out-of-register -sheets suggest a pathway to toxic amyloid aggregates
journal, December 2012

Shape Complementarity at Protein/Protein Interfaces
journal, December 1993

The Amyloid State of Proteins in Human Diseases
journal, March 2012

Structural Studies of Amyloid Proteins at the Molecular Level
journal, June 2017

Refinement of Macromolecular Structures by the Maximum-Likelihood Method
journal, May 1997

Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology
journal, January 2005

Molecular basis for amyloid- polymorphism
journal, September 2011

Atomic structure of a toxic, oligomeric segment of SOD1 linked to amyotrophic lateral sclerosis (ALS)
journal, July 2017

Transthyretin (Prealbumin) in Health and Disease: Nutritional Implications
journal, July 1994

Identifying the amylome, proteins capable of forming amyloid-like fibrils
journal, February 2010

Solvent-accessible surfaces of proteins and nucleic acids
journal, August 1983

Diagnosis, Prognosis, and Therapy of Transthyretin Amyloidosis
journal, December 2015

Atomic structure and hierarchical assembly of a cross- amyloid fibril
journal, March 2013

Atomic structures of amyloid cross-β spines reveal varied steric zippers
journal, April 2007

Relaxation of backbone bond geometry improves protein energy landscape modeling: Relaxation of Backbone Bond Geometry
journal, November 2013

Structure of prealbumin: Secondary, tertiary and quaternary interactions determined by Fourier refinement at 1.8 Å
journal, May 1978

Structure-based inhibitors of tau aggregation
journal, November 2017

Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage
journal, January 2015

Atomic View of a Toxic Amyloid Small Oligomer
journal, March 2012

The interpretation of protein structures: Estimation of static accessibility
journal, February 1971

Common core structure of amyloid fibrils by synchrotron X-ray diffraction 1 1Edited by F. E. Cohen
journal, October 1997

Molecular mechanisms for protein-encoded inheritance
journal, August 2009

Crystal Structures of IAPP Amyloidogenic Segments Reveal a Novel Packing Motif of Out-of-Register Beta Sheets
journal, January 2016

Automated Structure Solution with the PHENIX Suite
book, January 2008

The 3D profile method for identifying fibril-forming segments of proteins
journal, March 2006

Structure of the cross-β spine of amyloid-like fibrils
journal, June 2005

Phaser crystallographic software
journal, July 2007

A new amyloidogenic transthyretin variant, [D38A], detected by electrospray ionization / mass spectrometry
journal, January 1999

Peptide probes detect misfolded transthyretin oligomers in plasma of hereditary amyloidosis patients
journal, September 2017