Synthetic Biology for Therapeutic Applications
- Department of Biochemistry, ‡Department of Chemical and Biomolecular Engineering, and §Department of Bioengineering, Department of Chemistry, Center for Biophysics and Computational Biology and Institute for Genomic Biology, University of Illinois at Urbana−Champaign, 600 South Mathews Avenue, Urbana, Illinois 61801, United States
Synthetic biology is a relatively new field with the key aim of designing and constructing biological systems with novel functionalities. Today, synthetic biology devices are making their first steps in contributing new solutions to a number of biomedical challenges, such as emerging bacterial antibiotic resistance and cancer therapy. This review discusses some synthetic biology approaches and applications that were recently used in disease mechanism investigation and disease modeling, drug discovery and production, as well as vaccine development and treatment of infectious diseases, cancer, and metabolic disorders.
- Research Organization:
- Univ. of Illinois at Urbana-Champaign, IL (United States)
- Sponsoring Organization:
- USDOE Office of Science (SC), Biological and Environmental Research (BER); National Inst. of Health (NIH) (United States); Defense Advanced Research Projects Agency (DARPA) (United States)
- Grant/Contract Number:
- SC0008743; GM077596
- OSTI ID:
- 1158718
- Alternate ID(s):
- OSTI ID: 1455064
- Journal Information:
- Molecular Pharmaceutics, Journal Name: Molecular Pharmaceutics Vol. 12 Journal Issue: 2; ISSN 1543-8384
- Publisher:
- American Chemical SocietyCopyright Statement
- Country of Publication:
- United States
- Language:
- English
Cited by: 15 works
Citation information provided by
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