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Title: Production of high specific activity radiolanthanides for medical purposes using the UC Irvine TRIGA reactor

Abstract

Radioactive lanthanides have become an important imaging, diagnostic and therapeutic tool in the medical field. The objective of our research was to investigate the feasibility of producing radioactive lanthanides with high specific activity in a small-scale research reactor using the Szilard–Chalmers method. The results indicate that the activated nuclides recoil out of the target after neutron capture and we obtain enrichment of the radionuclide compared to the bulk irradiation. These first attempts, result in enrichment factors and yields that are low but indicates a possibility of using this technique if the method is further optimized.

Authors:
 [1];  [2];  [1]
  1. Univ. of California, Irvine, CA (United States). Dept. of Chemical Engineering and Materials Science
  2. Univ. of California, Irvine, CA (United States). Dept. of Chemistry
Publication Date:
Research Org.:
Univ. of California, Irvine, CA (United States)
Sponsoring Org.:
U.S. Nuclear Regulatory Commission (NRC)
OSTI Identifier:
1454600
DOE Contract Number:  
NRC-HQ-11-G-38-0037
Resource Type:
Journal Article
Journal Name:
Journal of Radioanalytical and Nuclear Chemistry
Additional Journal Information:
Journal Volume: 303; Journal Issue: 2; Journal ID: ISSN 0236-5731
Publisher:
Springer
Country of Publication:
United States
Language:
English
Subject:
62 RADIOLOGY AND NUCLEAR MEDICINE; 38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; Medical radiolanthanides; Szilard–Chalmers; TRIGA reactor; Nuclear medicine

Citation Formats

Safavi-Tehrani, Leila, Miller, George E., and Nilsson, Mikael. Production of high specific activity radiolanthanides for medical purposes using the UC Irvine TRIGA reactor. United States: N. p., 2014. Web. doi:10.1007/s10967-014-3486-2.
Safavi-Tehrani, Leila, Miller, George E., & Nilsson, Mikael. Production of high specific activity radiolanthanides for medical purposes using the UC Irvine TRIGA reactor. United States. doi:10.1007/s10967-014-3486-2.
Safavi-Tehrani, Leila, Miller, George E., and Nilsson, Mikael. Sun . "Production of high specific activity radiolanthanides for medical purposes using the UC Irvine TRIGA reactor". United States. doi:10.1007/s10967-014-3486-2.
@article{osti_1454600,
title = {Production of high specific activity radiolanthanides for medical purposes using the UC Irvine TRIGA reactor},
author = {Safavi-Tehrani, Leila and Miller, George E. and Nilsson, Mikael},
abstractNote = {Radioactive lanthanides have become an important imaging, diagnostic and therapeutic tool in the medical field. The objective of our research was to investigate the feasibility of producing radioactive lanthanides with high specific activity in a small-scale research reactor using the Szilard–Chalmers method. The results indicate that the activated nuclides recoil out of the target after neutron capture and we obtain enrichment of the radionuclide compared to the bulk irradiation. These first attempts, result in enrichment factors and yields that are low but indicates a possibility of using this technique if the method is further optimized.},
doi = {10.1007/s10967-014-3486-2},
journal = {Journal of Radioanalytical and Nuclear Chemistry},
issn = {0236-5731},
number = 2,
volume = 303,
place = {United States},
year = {2014},
month = {8}
}

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