Production of high specific activity radiolanthanides for medical purposes using the UC Irvine TRIGA reactor

Journal Article · Sun Aug 31 00:00:00 EDT 2014 · Journal of Radioanalytical and Nuclear Chemistry

DOI:https://doi.org/10.1007/s10967-014-3486-2· OSTI ID:1454600

Safavi-Tehrani, Leila ^[1]; Miller, George E. ^[2]; Nilsson, Mikael ^[1]

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1. Univ. of California, Irvine, CA (United States). Dept. of Chemical Engineering and Materials Science
2. Univ. of California, Irvine, CA (United States). Dept. of Chemistry

Radioactive lanthanides have become an important imaging, diagnostic and therapeutic tool in the medical field. The objective of our research was to investigate the feasibility of producing radioactive lanthanides with high specific activity in a small-scale research reactor using the Szilard–Chalmers method. The results indicate that the activated nuclides recoil out of the target after neutron capture and we obtain enrichment of the radionuclide compared to the bulk irradiation. These first attempts, result in enrichment factors and yields that are low but indicates a possibility of using this technique if the method is further optimized.

• Research Organization: Univ. of California, Irvine, CA (United States)
• Sponsoring Organization: U.S. Nuclear Regulatory Commission (NRC)
• DOE Contract Number: NRC-HQ-11-G-38-0037
• OSTI ID: 1454600
• Journal Information: Journal of Radioanalytical and Nuclear Chemistry, Vol. 303, Issue 2; ISSN 0236-5731
• Publisher: Springer
• Country of Publication: United States
• Language: English

Related Subjects

62 RADIOLOGY AND NUCLEAR MEDICINE
38 RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY
Medical radiolanthanides
Szilard–Chalmers
TRIGA reactor
Nuclear medicine