Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor

Huang, Jianyun; Dey, Raja; Wang, Yufeng; Jakoncic, Jean; Kurinov, Igor; Huang, Xin-Yun

doi:10.1016/j.jmb.2018.03.009

Title: Structural Insights into the Induced-fit Inhibition of Fascin by a Small-Molecule Inhibitor

Journal Article · Sun Apr 01 00:00:00 EDT 2018 · Journal of Molecular Biology

DOI:https://doi.org/10.1016/j.jmb.2018.03.009· OSTI ID:1452846

Huang, Jianyun; Dey, Raja; Wang, Yufeng; Jakoncic, Jean; Kurinov, Igor; Huang, Xin-Yun

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Research Organization:: Argonne National Laboratory (ANL), Argonne, IL (United States). Advanced Photon Source (APS)

Sponsoring Organization:: National Institutes of Health (NIH)

OSTI ID:: 1452846

Journal Information:: Journal of Molecular Biology, Vol. 430, Issue 9; ISSN 0022-2836

Publisher:: Elsevier

Country of Publication:: United States

Language:: ENGLISH

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Novel anti-invasive properties of a Fascin1 inhibitor on colorectal cancer cells Montoro-García, Silvia; Alburquerque-González, Begoña; Bernabé-García, Ángel Journal of Molecular Medicine, Vol. 98, Issue 3 https://doi.org/10.1007/s00109-020-01877-z	journal	January 2020
Structure-based design, synthesis and biological evaluation of a novel series of isoquinolone and pyrazolo[4,3-c]pyridine inhibitors of fascin 1 as potential anti-metastatic agents Francis, Stuart; Croft, Daniel; Schüttelkopf, Alexander W. Bioorganic & Medicinal Chemistry Letters, Vol. 29, Issue 8 https://doi.org/10.1016/j.bmcl.2019.01.035	journal	April 2019
Knockdown of Ski decreases osteosarcoma cell proliferation and migration by suppressing the PI3K/Akt signaling pathway Zhao, Xin; Fang, Yuying; Wang, Xingwen International Journal of Oncology https://doi.org/10.3892/ijo.2019.4914	journal	November 2019

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