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Title: Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design

Authors:
 [1];  [2]; ORCiD logo [3];  [4]; ORCiD logo [5]; ORCiD logo [2];  [6];  [7]; ORCiD logo [1]
  1. Department of Biochemistry &, Structural Biology, Lund University, S-221 00 Lund, Sweden
  2. Department of Biophysical Chemistry, Lund University, S-221 00 Lund, Sweden
  3. Jülich Centre for Neutron Science (JCNS) at Heinz Maier-Leibnitz Zentrum (MLZ), Forschungszentrum Jülich GmbH, Lichtenbergstrasse 1, 85747 Garching, Germany
  4. Heinz Maier-Leibnitz Zentrum (MLZ), Technische Universität München, Lichtenbergstrasse 1, 85748 Garching, Germany
  5. Neutron Scattering Division, Oak Ridge National Laboratory, 1 Bethel Valley Road, Oak Ridge, Tennessee 37831, United States
  6. Institut Laue-Langevin, 71 avenue des Martyrs, 38000 Grenoble, France
  7. Department of Biochemistry &, Structural Biology, Lund University, S-221 00 Lund, Sweden, Instrument Division, European Spallation Source ERIC, Box 176, S-221 00 Lund, Sweden
Publication Date:
Sponsoring Org.:
USDOE Office of Science (SC), Basic Energy Sciences (BES) (SC-22)
OSTI Identifier:
1438966
Resource Type:
Journal Article: Published Article
Journal Name:
Journal of Medicinal Chemistry
Additional Journal Information:
Journal Name: Journal of Medicinal Chemistry Journal Volume: 61 Journal Issue: 10; Journal ID: ISSN 0022-2623
Publisher:
American Chemical Society
Country of Publication:
United States
Language:
English

Citation Formats

Manzoni, Francesco, Wallerstein, Johan, Schrader, Tobias E., Ostermann, Andreas, Coates, Leighton, Akke, Mikael, Blakeley, Matthew P., Oksanen, Esko, and Logan, Derek T.. Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. United States: N. p., 2018. Web. doi:10.1021/acs.jmedchem.8b00081.
Manzoni, Francesco, Wallerstein, Johan, Schrader, Tobias E., Ostermann, Andreas, Coates, Leighton, Akke, Mikael, Blakeley, Matthew P., Oksanen, Esko, & Logan, Derek T.. Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design. United States. doi:10.1021/acs.jmedchem.8b00081.
Manzoni, Francesco, Wallerstein, Johan, Schrader, Tobias E., Ostermann, Andreas, Coates, Leighton, Akke, Mikael, Blakeley, Matthew P., Oksanen, Esko, and Logan, Derek T.. Thu . "Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design". United States. doi:10.1021/acs.jmedchem.8b00081.
@article{osti_1438966,
title = {Elucidation of Hydrogen Bonding Patterns in Ligand-Free, Lactose- and Glycerol-Bound Galectin-3C by Neutron Crystallography to Guide Drug Design},
author = {Manzoni, Francesco and Wallerstein, Johan and Schrader, Tobias E. and Ostermann, Andreas and Coates, Leighton and Akke, Mikael and Blakeley, Matthew P. and Oksanen, Esko and Logan, Derek T.},
abstractNote = {},
doi = {10.1021/acs.jmedchem.8b00081},
journal = {Journal of Medicinal Chemistry},
number = 10,
volume = 61,
place = {United States},
year = {Thu Apr 19 00:00:00 EDT 2018},
month = {Thu Apr 19 00:00:00 EDT 2018}
}

Journal Article:
Free Publicly Available Full Text
Publisher's Version of Record at 10.1021/acs.jmedchem.8b00081

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