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Title: Recyclable Cu(i)/melanin dots for cycloaddition, bioconjugation and cell labelling

Abstract

We successfully transferred melanin into a novel catalytic platform. Ligand-free, water-soluble, recyclable and biocompatible Cu(i)-loaded melanin dots [Cu(i)/M-dots] was easily prepared and demonstrate excellent properties for classic CuAAC, bioconjugation and cell labelling.

Authors:
 [1];  [2];  [2];  [2];  [2];  [2];  [3];  [3];  [4];  [2]
  1. Stanford University, Stanford, CA (United States); Wuhan Univ. School of Pharmaceutical Sciences, Wuhan (China)
  2. Stanford University, Stanford, CA (United States)
  3. Chinese Academy of Medical Science, Beijing (China)
  4. Wuhan Univ. School of Pharmaceutical Sciences, Wuhan (China)
Publication Date:
Research Org.:
Stanford University, Stanford, CA (United States). Molecular Imaging Program at Stanford (MIPS), Bio-X Program, Department of Radiology, Canary Center at Stanford for Cancer Early Detection
Sponsoring Org.:
USDOE Office of Science (SC), Biological and Environmental Research (BER) (SC-23)
OSTI Identifier:
1437938
Grant/Contract Number:  
SC0008397
Resource Type:
Journal Article: Accepted Manuscript
Journal Name:
Chemical Science
Additional Journal Information:
Journal Volume: 7; Journal Issue: 9; Journal ID: ISSN 2041-6520
Publisher:
Royal Society of Chemistry
Country of Publication:
United States
Language:
English
Subject:
59 BASIC BIOLOGICAL SCIENCES

Citation Formats

Sun, Yao, Hong, Suhyun, Ma, Xiaowei, Cheng, Kai, Wang, Jing, Zhang, Zhe, Yang, Meng, Jiang, Yuxin, Hong, Xuechuan, and Cheng, Zhen. Recyclable Cu(i)/melanin dots for cycloaddition, bioconjugation and cell labelling. United States: N. p., 2016. Web. doi:10.1039/c6sc01536k.
Sun, Yao, Hong, Suhyun, Ma, Xiaowei, Cheng, Kai, Wang, Jing, Zhang, Zhe, Yang, Meng, Jiang, Yuxin, Hong, Xuechuan, & Cheng, Zhen. Recyclable Cu(i)/melanin dots for cycloaddition, bioconjugation and cell labelling. United States. doi:10.1039/c6sc01536k.
Sun, Yao, Hong, Suhyun, Ma, Xiaowei, Cheng, Kai, Wang, Jing, Zhang, Zhe, Yang, Meng, Jiang, Yuxin, Hong, Xuechuan, and Cheng, Zhen. Fri . "Recyclable Cu(i)/melanin dots for cycloaddition, bioconjugation and cell labelling". United States. doi:10.1039/c6sc01536k. https://www.osti.gov/servlets/purl/1437938.
@article{osti_1437938,
title = {Recyclable Cu(i)/melanin dots for cycloaddition, bioconjugation and cell labelling},
author = {Sun, Yao and Hong, Suhyun and Ma, Xiaowei and Cheng, Kai and Wang, Jing and Zhang, Zhe and Yang, Meng and Jiang, Yuxin and Hong, Xuechuan and Cheng, Zhen},
abstractNote = {We successfully transferred melanin into a novel catalytic platform. Ligand-free, water-soluble, recyclable and biocompatible Cu(i)-loaded melanin dots [Cu(i)/M-dots] was easily prepared and demonstrate excellent properties for classic CuAAC, bioconjugation and cell labelling.},
doi = {10.1039/c6sc01536k},
journal = {Chemical Science},
number = 9,
volume = 7,
place = {United States},
year = {Fri May 20 00:00:00 EDT 2016},
month = {Fri May 20 00:00:00 EDT 2016}
}

Journal Article:
Free Publicly Available Full Text
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Cited by: 13 works
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Works referenced in this record:

Click Chemistry: Diverse Chemical Function from a Few Good Reactions
journal, June 2001


Peptidotriazoles on Solid Phase  [1,2,3]-Triazoles by Regiospecific Copper(I)-Catalyzed 1,3-Dipolar Cycloadditions of Terminal Alkynes to Azides
journal, May 2002

  • Tornøe, Christian W.; Christensen, Caspar; Meldal, Morten
  • The Journal of Organic Chemistry, Vol. 67, Issue 9, p. 3057-3064
  • DOI: 10.1021/jo011148j