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Title: “Candidatus Paraporphyromonas polyenzymogenes” encodes multi-modular cellulases linked to the type IX secretion system

Abstract

In Nature, obligate herbivorous ruminants have a close symbiotic relationship with their gastrointestinal microbiome, which proficiently deconstructs plant biomass. Despite decades of research, lignocellulose degradation in the rumen has thus far been attributed to a limited number of culturable microorganisms. Here, we combine meta-omics and enzymology to identify and describe a novel Bacteroidetes family (“Candidatus MH11”) composed entirely of uncultivated strains that are predominant in ruminants and only distantly related to previously characterized taxa.

Authors:
; ; ; ; ; ; ; ; ; ; ; ; ; ;
Publication Date:
Research Org.:
Pacific Northwest National Laboratory (PNNL), Richland, WA (US), Environmental Molecular Sciences Laboratory (EMSL)
Sponsoring Org.:
USDOE
OSTI Identifier:
1437543
Report Number(s):
PNNL-SA-133703
Journal ID: ISSN 2049-2618; 48642; KP1704020
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Journal Article
Journal Name:
Microbiome
Additional Journal Information:
Journal Volume: 6; Journal Issue: 1; Journal ID: ISSN 2049-2618
Publisher:
BioMed Central
Country of Publication:
United States
Language:
English
Subject:
Type IX secretion system; Carbohydrate-active enzymes; Cellulases; Bacteroidetes; Environmental Molecular Sciences Laboratory

Citation Formats

Naas, A. E., Solden, L. M., Norbeck, A. D., Brewer, H., Hagen, L. H., Heggenes, I. M., McHardy, A. C., Mackie, R. I., Paša-Tolić, L., Arntzen, M. Ø., Eijsink, V. G. H., Koropatkin, N. M., Hess, M., Wrighton, K. C., and Pope, P. B. “Candidatus Paraporphyromonas polyenzymogenes” encodes multi-modular cellulases linked to the type IX secretion system. United States: N. p., 2018. Web. doi:10.1186/s40168-018-0421-8.
Naas, A. E., Solden, L. M., Norbeck, A. D., Brewer, H., Hagen, L. H., Heggenes, I. M., McHardy, A. C., Mackie, R. I., Paša-Tolić, L., Arntzen, M. Ø., Eijsink, V. G. H., Koropatkin, N. M., Hess, M., Wrighton, K. C., & Pope, P. B. “Candidatus Paraporphyromonas polyenzymogenes” encodes multi-modular cellulases linked to the type IX secretion system. United States. doi:10.1186/s40168-018-0421-8.
Naas, A. E., Solden, L. M., Norbeck, A. D., Brewer, H., Hagen, L. H., Heggenes, I. M., McHardy, A. C., Mackie, R. I., Paša-Tolić, L., Arntzen, M. Ø., Eijsink, V. G. H., Koropatkin, N. M., Hess, M., Wrighton, K. C., and Pope, P. B. Thu . "“Candidatus Paraporphyromonas polyenzymogenes” encodes multi-modular cellulases linked to the type IX secretion system". United States. doi:10.1186/s40168-018-0421-8.
@article{osti_1437543,
title = {“Candidatus Paraporphyromonas polyenzymogenes” encodes multi-modular cellulases linked to the type IX secretion system},
author = {Naas, A. E. and Solden, L. M. and Norbeck, A. D. and Brewer, H. and Hagen, L. H. and Heggenes, I. M. and McHardy, A. C. and Mackie, R. I. and Paša-Tolić, L. and Arntzen, M. Ø. and Eijsink, V. G. H. and Koropatkin, N. M. and Hess, M. and Wrighton, K. C. and Pope, P. B.},
abstractNote = {In Nature, obligate herbivorous ruminants have a close symbiotic relationship with their gastrointestinal microbiome, which proficiently deconstructs plant biomass. Despite decades of research, lignocellulose degradation in the rumen has thus far been attributed to a limited number of culturable microorganisms. Here, we combine meta-omics and enzymology to identify and describe a novel Bacteroidetes family (“Candidatus MH11”) composed entirely of uncultivated strains that are predominant in ruminants and only distantly related to previously characterized taxa.},
doi = {10.1186/s40168-018-0421-8},
journal = {Microbiome},
issn = {2049-2618},
number = 1,
volume = 6,
place = {United States},
year = {2018},
month = {3}
}

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