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Title: Improvement of a Mixture Experiment Model Relating the Component Proportions to the Size of Nanonized Itraconazole Particles in Extemporary Suspensions

Abstract

The Foglio Bonda et al. (2016) (henceforth FB) paper discussed the use of mixture experiment design and modeling methods to study how the proportions of three components in an extemporaneous oral suspension affected the mean diameter of drug particles (the response variable of interest). The three components were itraconazole (ITZ), Tween 20 (TW20), and Methocel® E5 (E5). After publication of the FB paper, the second author of this corrigendum (not an author of the original paper) contacted the corresponding author to point out some errors as well as insufficient explanations in parts of the paper. This corrigendum was prepared to address these issues. The authors of the original paper apologize for any inconveniences to readers.

Authors:
; ;
Publication Date:
Research Org.:
Pacific Northwest National Lab. (PNNL), Richland, WA (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1436844
Report Number(s):
PNNL-SA-123916
830403000
DOE Contract Number:  
AC05-76RL01830
Resource Type:
Journal Article
Resource Relation:
Journal Name: European Journal of Pharmaceutical Sciences, 117:297-300
Country of Publication:
United States
Language:
English
Subject:
mixture experiment; mixture experiment design; mixture experimental modeling; oral suspension; nano particles

Citation Formats

Pattarino, Franco, Piepel, Gregory F., and Rinaldi, Maurizio. Improvement of a Mixture Experiment Model Relating the Component Proportions to the Size of Nanonized Itraconazole Particles in Extemporary Suspensions. United States: N. p., 2018. Web. doi:10.1016/j.ejps.2018.03.005.
Pattarino, Franco, Piepel, Gregory F., & Rinaldi, Maurizio. Improvement of a Mixture Experiment Model Relating the Component Proportions to the Size of Nanonized Itraconazole Particles in Extemporary Suspensions. United States. doi:10.1016/j.ejps.2018.03.005.
Pattarino, Franco, Piepel, Gregory F., and Rinaldi, Maurizio. Tue . "Improvement of a Mixture Experiment Model Relating the Component Proportions to the Size of Nanonized Itraconazole Particles in Extemporary Suspensions". United States. doi:10.1016/j.ejps.2018.03.005.
@article{osti_1436844,
title = {Improvement of a Mixture Experiment Model Relating the Component Proportions to the Size of Nanonized Itraconazole Particles in Extemporary Suspensions},
author = {Pattarino, Franco and Piepel, Gregory F. and Rinaldi, Maurizio},
abstractNote = {The Foglio Bonda et al. (2016) (henceforth FB) paper discussed the use of mixture experiment design and modeling methods to study how the proportions of three components in an extemporaneous oral suspension affected the mean diameter of drug particles (the response variable of interest). The three components were itraconazole (ITZ), Tween 20 (TW20), and Methocel® E5 (E5). After publication of the FB paper, the second author of this corrigendum (not an author of the original paper) contacted the corresponding author to point out some errors as well as insufficient explanations in parts of the paper. This corrigendum was prepared to address these issues. The authors of the original paper apologize for any inconveniences to readers.},
doi = {10.1016/j.ejps.2018.03.005},
journal = {European Journal of Pharmaceutical Sciences, 117:297-300},
number = ,
volume = ,
place = {United States},
year = {Tue May 01 00:00:00 EDT 2018},
month = {Tue May 01 00:00:00 EDT 2018}
}