TAZ: a novel transcriptional co-activator regulated by interactions with 14-3-3 and PDZ domain proteins
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December 2000 |
The Hippo pathway effectors TAZ and YAP in development, homeostasis and disease
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April 2014 |
Cyclic stretch promotes osteogenesis-related gene expression in osteoblast-like cells through a cofilin-associated mechanism
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May 2016 |
A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis: Cell-adhesion GPCRs mediates autoproteolysis
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February 2012 |
TAZ Promotes PC2 Degradation through a SCF -Trcp E3 Ligase Complex
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July 2007 |
Mechanical Strain Inhibits Adipogenesis in Mesenchymal Stem Cells by Stimulating a Durable β-Catenin Signal
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December 2008 |
Kif3a Deficiency Reverses the Skeletal Abnormalities in Pkd1 Deficient Mice by Restoring the Balance Between Osteogenesis and Adipogenesis
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December 2010 |
Role of YAP/TAZ in mechanotransduction
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June 2011 |
Physiological mechanisms and therapeutic potential of bone mechanosensing
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June 2015 |
The Molecular Basis of Focal Cyst Formation in Human Autosomal Dominant Polycystic Kidney Disease Type I
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December 1996 |
Dose-Dependent Effects of Runx2 on Bone Development
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November 2009 |
Genetic evidence for a trans-heterozygous model for cystogenesis in autosomal dominant polycystic kidney disease
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February 2000 |
Mechanical stimulation promote the osteogenic differentiation of bone marrow stromal cells through epigenetic regulation of Sonic Hedgehog
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March 2017 |
Wnt and PPARγ signaling in osteoblastogenesis and adipogenesis
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July 2009 |
Two distinct osteoblast-specific cis-acting elements control expression of a mouse osteocalcin gene.
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April 1995 |
Polycystin-1 C-terminal Cleavage Is Modulated by Polycystin-2 Expression
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June 2009 |
Osteoblast-Specific Deletion of Pkd2 Leads to Low-Turnover Osteopenia and Reduced Bone Marrow Adiposity
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December 2014 |
Transcriptional Coactivation of Bone-Specific Transcription Factor Cbfa1 by TAZ
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February 2003 |
Polycystin-1, STAT6, and P100 Function in a Pathway that Transduces Ciliary Mechanosensation and Is Activated in Polycystic Kidney Disease
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January 2006 |
Partial Purification and Characterization of γ-Secretase from Post-mortem Human Brain
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April 2003 |
Osteoblast-Targeted Overexpression of TAZ Increases Bone Mass In Vivo
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February 2013 |
Analysis of a tissue-specific enhancer: ARF6 regulates adipogenic gene expression.
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March 1992 |
Bicc1 is a genetic determinant of osteoblastogenesis and bone mineral density
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May 2014 |
Identification and Specification of the Mouse Skeletal Stem Cell
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January 2015 |
Mechanical Loading Down-Regulates Peroxisome Proliferator-Activated Receptor γ in Bone Marrow Stromal Cells and Favors Osteoblastogenesis at the Expense of Adipogenesis
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May 2007 |
Modeled Microgravity Inhibits Osteogenic Differentiation of Human Mesenchymal Stem Cells and Increases Adipogenesis
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May 2004 |
PKD1 interacts with PKD2 through a probable coiled-coil domain
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June 1997 |
Polycystin-1 Regulates Skeletogenesis through Stimulation of the Osteoblast-specific Transcription Factor RUNX2 -II
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March 2008 |
Homo- and heterodimeric interactions between the gene products of PKD1 and PKD2
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June 1997 |
Mechanical stimuli induce cleavage and nuclear translocation of the polycystin-1 C terminus
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November 2004 |
Aging activates adipogenic and suppresses osteogenic programs in mesenchymal marrow stroma/stem cells: the role of PPAR-γ2 transcription factor and TGF-β/BMP signaling pathways: Aging alters the differentiation potential of mMSC, E. J. Moerman et al.
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October 2004 |
Mechanical Allostery: Evidence for a Force Requirement in the Proteolytic Activation of Notch
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June 2015 |
Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach
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June 2011 |
Augmentation of PPARγ-TAZ interaction contributes to the anti-adipogenic activity of KR62980
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November 2009 |
Polycystin-1 cleavage and the regulation of transcriptional pathways
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July 2013 |
Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects
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October 2001 |
Effect of asymmetric dimethylarginine on osteoblastic differentiation
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November 2001 |
Conditional deletion of Pkd1 in osteocytes disrupts skeletal mechanosensing in mice
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July 2011 |
Polycystin-1 Mediates Mechanical Strain-Induced Osteoblastic Mechanoresponses via Potentiation of Intracellular Calcium and Akt/β-Catenin Pathway
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March 2014 |
The Remarkable Mechanical Strength of Polycystin-1 Supports a Direct Role in Mechanotransduction
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June 2005 |
Expression of PKD1 and PKD2 Transcripts and Proteins in Human Embryo and during Normal Kidney Development
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March 2002 |
Mechanical stimulation of polycystin-1 induces human osteoblastic gene expression via potentiation of the calcineurin/NFAT signaling axis
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September 2012 |
Co-assembly of polycystin-1 and -2 produces unique cation-permeable currents
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December 2000 |
A computationally identified compound antagonizes excess FGF-23 signaling in renal tubules and a mouse model of hypophosphatemia
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November 2016 |
Context-dependent switch in chemo/mechanotransduction via multilevel crosstalk among cytoskeleton-regulated MRTF and TAZ and TGFβ-regulated Smad3
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May 2016 |
TAZ, a Transcriptional Modulator of Mesenchymal Stem Cell Differentiation
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August 2005 |
Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals
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October 2007 |
Cilia-like Structures and Polycystin-1 in Osteoblasts/Osteocytes and Associated Abnormalities in Skeletogenesis and Runx2 Expression
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August 2006 |
Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells
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January 2003 |
Intermittent Traction Stretch Promotes the Osteoblastic Differentiation of Bone Mesenchymal Stem Cells by the ERK1/2-Activated Cbfa1 Pathway
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July 2012 |
Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1
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January 2007 |
Osf2/Cbfa1: A Transcriptional Activator of Osteoblast Differentiation
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May 1997 |
Parathyroid hormone 1-34 and skeletal anabolic action: The use of parathyroid hormone in bone formation
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January 2017 |
Yap- and Cdc42-Dependent Nephrogenesis and Morphogenesis during Mouse Kidney Development
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March 2013 |
The γ-Secretase Cleavage Product of Polycystin-1 Regulates TCF and CHOP-Mediated Transcriptional Activation through a p300-Dependent Mechanism
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January 2012 |
Ensemble-based docking: From hit discovery to metabolism and toxicity predictions
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October 2016 |
Cardiovascular, skeletal, and renal defects in mice with a targeted disruption of the Pkd1 gene
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October 2001 |
Conditional Disruption of Pkd1 in Osteoblasts Results in Osteopenia Due to Direct Impairment of Bone Formation
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November 2009 |
Mechanosensor polycystin-1 potentiates differentiation of human osteoblastic cells by upregulating Runx2 expression via induction of JAK2/STAT3 signaling axis
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October 2016 |
Extremely low frequency magnetic fields inhibit adipogenesis of human mesenchymal stem cells: ELF-MF Inhibits Adipogenesis of Human MSCs
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September 2014 |
Multiple postnatal craniofacial anomalies are characterized by conditional loss of polycystic kidney disease 2 (Pkd2)
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February 2013 |
The Cleaved Cytoplasmic Tail of Polycystin-1 Regulates Src-Dependent STAT3 Activation
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February 2014 |
Mechanical stretch inhibits mesenchymal stem cell adipogenic differentiation through TGFβ1/Smad2 signaling
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October 2015 |
A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors
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August 2013 |
Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ
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March 2008 |
Somatic Mutation in Individual Liver Cysts Supports a Two-Hit Model of Cystogenesis in Autosomal Dominant Polycystic Kidney Disease
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August 1998 |
Role of TAZ as Mediator of Wnt Signaling
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December 2012 |
A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1
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October 2007 |
Conditional Mutation of Pkd2 Causes Cystogenesis and Upregulates β-Catenin
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November 2009 |