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Title: Uses of monoclonal antibody 8H9

Abstract

This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention provides a pharmaceutical composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a pharmaceutically acceptable carrier. This invention also provides an antibody other than the monoclonal antibody 8H9 comprising the complementary determining regions of monoclonal antibody 8H9 or a derivative thereof, capable of binding to the same antigen as the monoclonal antibody 8H9. This invention provides a substance capable of competitively inhibiting the binding of monoclonal antibody 8H9. This invention also provides an isolated scFv of monoclonal antibody 8H9 or a derivative thereof. This invention also provides the 8H9 antigen. This invention also provides a method of inhibiting the growth of tumor cells comprising contacting said tumor cells with an appropriate amount of monoclonal antibody 8H9 or a derivative thereof.

Inventors:
Publication Date:
Research Org.:
Sloan-Kettering Institute for Cancer Research, New York, NY (United States)
Sponsoring Org.:
USDOE
OSTI Identifier:
1434705
Patent Number(s):
9,938,351
Application Number:
15/365,803
Assignee:
Sloan-Kettering Institute for Cancer Research (New York, NY) CHO
DOE Contract Number:  
FG02-93ER61658
Resource Type:
Patent
Resource Relation:
Patent File Date: 2016 Nov 30
Country of Publication:
United States
Language:
English

Citation Formats

Cheung, Nai-Kong V. Uses of monoclonal antibody 8H9. United States: N. p., 2018. Web.
Cheung, Nai-Kong V. Uses of monoclonal antibody 8H9. United States.
Cheung, Nai-Kong V. Tue . "Uses of monoclonal antibody 8H9". United States. doi:. https://www.osti.gov/servlets/purl/1434705.
@article{osti_1434705,
title = {Uses of monoclonal antibody 8H9},
author = {Cheung, Nai-Kong V.},
abstractNote = {This invention provides a composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a suitable carrier. This invention provides a pharmaceutical composition comprising an effective amount of monoclonal antibody 8H9 or a derivative thereof and a pharmaceutically acceptable carrier. This invention also provides an antibody other than the monoclonal antibody 8H9 comprising the complementary determining regions of monoclonal antibody 8H9 or a derivative thereof, capable of binding to the same antigen as the monoclonal antibody 8H9. This invention provides a substance capable of competitively inhibiting the binding of monoclonal antibody 8H9. This invention also provides an isolated scFv of monoclonal antibody 8H9 or a derivative thereof. This invention also provides the 8H9 antigen. This invention also provides a method of inhibiting the growth of tumor cells comprising contacting said tumor cells with an appropriate amount of monoclonal antibody 8H9 or a derivative thereof.},
doi = {},
journal = {},
number = ,
volume = ,
place = {United States},
year = {Tue Apr 10 00:00:00 EDT 2018},
month = {Tue Apr 10 00:00:00 EDT 2018}
}

Patent:

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